The mediatization of the knowledge based economy : an Australian field based account

This paper presents an empirical account of mediatization from a Bourdieuian perspective, based on the development of a number of new concepts, such as cross-field effects and the rescaling of such effects as linked to processes of globalization. Built on an Australian empirical case relating to educational policy and the knowledge based economy, this paper argues that mediatization can be understood in relation to the cross-field effects of different fields of journalism on subsequent fields, which have their genesis in forms of practice that cross different social fields. Specifically, the case analysis details interactions between the field of print journalism and the field of policy over the course of an Australian science capability review, chaired by the then chief scientist, Dr Robin Batterham, which led to Australia adopting a national version of the knowledge economy. The empirical case also leads us to consider the impact of both global and national fields of journalism on fields of educational policy in relation to mediatization.

Potential applications of discrete-event simulation and fuzzy rule-based systems to structural reliability and availability

This chapter discusses and illustrates some potential applications of discrete-event simulation (DES) techniques in structural reliability and availability analysis, emphasizing the convenience of using probabilistic approaches in modern building and civil engineering practices. After reviewing existing literature on the topic, some advantages of probabilistic techniques over analytical ones are highlighted. Then, we introduce a general framework for performing structural reliability and availability analysis through DES. Our methodology proposes the use of statistical distributions and techniques – such as survival analysis – to model component-level reliability. Then, using failure- and repair-time distributions and information about the structural logical topology (which allows determination of the structural state from their components’ state), structural reliability, and availability information can be inferred. Two numerical examples illustrate some potential applications of the proposed methodology to achieving more reliable and structural designs. Finally, an alternative approach to model uncertainty at component level is also introduced as ongoing work. This new approach is based on the use of fuzzy rule-based systems and it allows the introduction of experts’ opinions and evaluations in our methodology.

A new monotonicity index for fuzzy rule-based systems

A search in the literature reveals that mathematical conditions (usually sufficient conditions) for the Fuzzy Inference System (FIS) models to satisfy the monotonicity property have been developed. A monotonically-ordered fuzzy rule base is important to maintain the monotonicity property of an FIS. However, it may difficult to obtain a monotonically-ordered fuzzy rule base in practice. We have previously introduced the idea of fuzzy rule relabeling to tackle this problem. In this paper, we further propose a monotonicity index for the FIS system, which serves as a metric to indicate the degree of a fuzzy rule base fulfilling the monotonicity property. The index is useful to provide an indication whether a fuzzy rule base should (or should not) be used in practice, even with fuzzy rule relabeling. To illustrate the idea, the zero-order Sugeno FIS model is exemplified. We add noise as errors into the fuzzy rule base to formulate a set of non-monotone fuzzy rules. As such, the metric also acts as a measure of noise in the fuzzy rule base. The results show that the proposed metric is useful to indicate the degree of a fuzzy rule base fulfilling the monotonicity property.

Knowledge-based automatic performance evaluation for medical training debriefing

 Manikin-based medical simulation has been shown to benefit the knowledge, skills and attitudes of the learner, and to impart favourable patient effects. A vital component of any training simulation is the after-session discussion with trainees to debrief their performance. In this study we develop a rule-based debriefing tool for improving the efficacy of medical training sessions. Unlike most existing de-briefing tools, the tool presented here has been designed to reduce medical trainer assessment time and to improve evaluation accuracy through a largely automated evaluation of trainee performance. The developed tool is acknowledged by the School of Medicine of Deakin University as an important advancement in assisting medical trainers carry out the debriefing process effectively and efficiently.

Diffusing knowledge-based core competencies for leveraging innovation strategies: modelling outsourcing to knowledge process organizations (KPOs) in pharmaceutical networks

As pharmaceutical firms try to market their products and reduce costs, vertically integrated structureshamper innovation processes. Yet, pharmaceutical firms must innovate to compete. Outsourcing knowledgeintensive activities to knowledge process organizations (KPOs) serves to reduce innovation process obstacles.Grounded in diffusion theory and strategic management literature, this conceptual paper explores fourinterrelated strategic concepts: core competencies, economies of scale and scope, knowledge sharing,and learning. This paper claims that (a) accumulated core competencies of multinational pharmaceuticalcompanies (MPCs) erode over time and these companies become dependent on KPOs (b) MPCs mustunderstand how KPOs manage core competencies (c) economies of scope benefit KPOs enabling them tosustain competitive advantages for their MPC partners, meanwhile the benefits from economies of both scaleand scope shift from MPCs to KPOs (d) KPOs need to monitor their rate of learning to remain competitive.The paper identifies implications for industrial managers and directions for future research.

Toward Omics-Based, Systems Biomedicine, and Path and Drug Discovery Methodologies for Depression-Inflammation Research.

Meta-analyses confirm that depression is accompanied by signs of inflammation including increased levels of acute phase proteins, e.g., C-reactive protein, and pro-inflammatory cytokines, e.g., interleukin-6. Supporting the translational significance of this, a meta-analysis showed that anti-inflammatory drugs may have antidepressant effects. Here, we argue that inflammation and depression research needs to get onto a new track. Firstly, the choice of inflammatory biomarkers in depression research was often too selective and did not consider the broader pathways. Secondly, although mild inflammatory responses are present in depression, other immune-related pathways cannot be disregarded as new drug targets, e.g., activation of cell-mediated immunity, oxidative and nitrosative stress (O&NS) pathways, autoimmune responses, bacterial translocation, and activation of the toll-like receptor and neuroprogressive pathways. Thirdly, anti-inflammatory treatments are sometimes used without full understanding of their effects on the broader pathways underpinning depression. Since many of the activated immune-inflammatory pathways in depression actually confer protection against an overzealous inflammatory response, targeting these pathways may result in unpredictable and unwanted results. Furthermore, this paper discusses the required improvements in research strategy, i.e., path and drug discovery processes, omics-based techniques, and systems biomedicine methodologies. Firstly, novel methods should be employed to examine the intracellular networks that control and modulate the immune, O&NS and neuroprogressive pathways using omics-based assays, including genomics, transcriptomics, proteomics, metabolomics, epigenomics, immunoproteomics and metagenomics. Secondly, systems biomedicine analyses are essential to unravel the complex interactions between these cellular networks, pathways, and the multifactorial trigger factors and to delineate new drug targets in the cellular networks or pathways. Drug discovery processes should delineate new drugs targeting the intracellular networks and immune-related pathways.

A community based systems diagram of obesity causes

INTRODUCTION: Application of system thinking to the development, implementation and evaluation of childhood obesity prevention efforts represents the cutting edge of community-based prevention. We report on an approach to developing a system oriented community perspective on the causes of obesity. METHODS: Group model building sessions were conducted in a rural Australian community to address increasing childhood obesity. Stakeholders (n = 12) built a community model that progressed from connection circles to causal loop diagrams using scripts from the system dynamics literature. Participants began this work in identifying change over time in causes and effects of childhood obesity within their community. The initial causal loop diagram was then reviewed and elaborated by 50 community leaders over a full day session. RESULTS: The process created a causal loop diagram representing community perceptions of determinants and causes of obesity. The causal loop diagram can be broken down into four separate domains; social influences; fast food and junk food; participation in sport; and general physical activity. DISCUSSION: This causal loop diagram can provide the basis for community led planning of a prevention response that engages with multiple levels of existing settings and systems.

KBRE: a framework for knowledge-based requirements engineering

Detecting inconsistencies is a critical part of requirements engineering (RE) and has been a topic of interest for several decades. Domain knowledge and semantics of requirements not only play important roles in elaborating requirements but are also a crucial way to detect conflicts among them. In this paper, we present a novel knowledge-based RE framework (KBRE) in which domain knowledge and semantics of requirements are central to elaboration, structuring, and management of captured requirements. Moreover, we also show how they facilitate the identification of requirements inconsistencies and other-related problems. In our KBRE model, description logic (DL) is used as the fundamental logical system for requirements analysis and reasoning. In addition, the application of DL in the form of Manchester OWL Syntax brings simplicity to the formalization of requirements while preserving sufficient expressive power. A tool has been developed and applied to an industrial use case to validate our approach.

Providing fairer resource allocation for multi-tenant cloud-based systems

A fundamental premise in cloud computing is trying to provide a more sophisticated computing resource sharing capability. In order to provide better allocation, the Dominant Resource Fairness (DRF) approach has been developed to address the "fair resource allocation problem" at the application layer for multi-tenant cloud applications. Nevertheless conventional DRF only considers the interplay of CPU and memory, which may result in over allocation of resources to one tenant's application to the detriment of others. In this paper, we propose an improved DRF algorithm with 3-dimensional demand vector to support disk resources as the third dominant shared resource, enhancing fairer resource sharing. Our technique is integrated with LINUX 'group' controls resource utilisation and realises data isolation to avoid undesirable interactions between co-located tasks. Our method ensures all tenants receive system resources fairly, which improves overall utilisation and throughput as well as reducing traffic in an over-crowded system. We evaluate the performance of different types of workload using different algorithms and compare ours to the default algorithm. Results show an increase of 15% resource utilisation and a reduction of 59% completion time on average, indicating that our DRF algorithm provides a better, smoother, fairer high-performance resource allocation scheme for both continuous workloads and batch jobs.

Study of ensemble strategies in discovering linear casual models

Determining the causal structure of a domain is frequently a key task in the area of Data Mining and Knowledge Discovery. This paper introduces ensemble learning into linear causal model discovery, then examines several algorithms based on different ensemble strategies including Bagging, Adaboost and GASEN. Experimental results show that (1) Ensemble discovery algorithm can achieve an improved result compared with individual causal discovery algorithm in terms of accuracy; (2) Among all examined ensemble discovery algorithms, BWV algorithm which uses a simple Bagging strategy works excellently compared to other more sophisticated ensemble strategies; (3) Ensemble method can also improve the stability of parameter estimation. In addition, Ensemble discovery algorithm is amenable to parallel and distributed processing, which is important for data mining in large data sets.

Information sharing between heterogeneous uncertain reasoning models in a multi-agent environment : a case study

The issue of information sharing and exchanging is one of the most important issues in the areas of artificial intelligence and knowledge-based systems (KBSs), or even in the broader areas of computer and information technology. This paper deals with a special case of this issue by carrying out a case study of information sharing between two well-known heterogeneous uncertain reasoning models: the certainty factor model and the subjective Bayesian method. More precisely, this paper discovers a family of exactly isomorphic transformations between these two uncertain reasoning models. More interestingly, among isomorphic transformation functions in this family, different ones can handle different degrees to which a domain expert is positive or negative when performing such a transformation task. The direct motivation of the investigation lies in a realistic consideration. In the past, expert systems exploited mainly these two models to deal with uncertainties. In other words, a lot of stand-alone expert systems which use the two uncertain reasoning models are available. If there is a reasonable transformation mechanism between these two uncertain reasoning models, we can use the Internet to couple these pre-existing expert systems together so that the integrated systems are able to exchange and share useful information with each other, thereby improving their performance through cooperation. Also, the issue of transformation between heterogeneous uncertain reasoning models is significant in the research area of multi-agent systems because different agents in a multi-agent system could employ different expert systems with heterogeneous uncertain reasonings for their action selections and the information sharing and exchanging is unavoidable between different agents. In addition, we make clear the relationship between the certainty factor model and probability theory.