A question of self-preservation : immunopathology in influenza virus infection

Influenza A viruses that circulate normally in the human population cause a debilitating, though generally transient, illness that is sometimes fatal, particularly in the elderly. Severe complications arising from pandemic influenza or the highly pathogenic avian H5N1 viruses are often associated with rapid, massive inflammatory cell infiltration, acute respiratory distress, reactive hemophagocytosis and multiple organ involvement. Histological and pathological indicators strongly suggest a key role for an excessive host response in mediating at least some of this pathology. Here, we review the current literature on how various effector arms of the immune system can act deleteriously to initiate or exacerbate pathological damage in this viral pneumonia. Generally, the same immunological factors mediating tissue damage during the anti-influenza immune response are also critical for efficient elimination of virus, thereby posing a significant challenge in the design of harmless yet effective therapeutic strategies for tackling influenza virus.

Managing industrial world heritage sites : preservation, presentation and sustainability

This thesis uses case study methodology to explore how the concept of sustainable development is being applied at industrial World Heritage sites. The thesis proposes a model of sustainable heritage management that is relevant to industrial heritage sites, as well as to other complex heritage sites, including historic urban landscapes.

Comments on "finite-time stability theorem of stochastic nonlinear systems" [Automatica 46 (2010) 2105-2108]

In this comment, we will point out some errors existing in Chen and Jiao (2010) from definitions to the proof of the main result, where the authors discussed the finite-time stability of stochastic nonlinear systems and proved a Lyapunov theorem on the finitetime stability.

A finite-time stability theorem of stochastic nonlinear systems and stabilization designs

This paper focuses on the finite-time stability and stabilization designs of stochastic nonlinear systems. We first present and discuss a definition on the finite-time stability in probability of stochastic nonlinear systems, then we introduce a stochastic Lyapunov theorem on the finite-time stability, which has been established by Yin et al. We also employ this theorem to design a continuous state feedback controller that makes a class of stochastic nonlinear systems to be stable in finite time. An example and a simulation are given to illustrate the theoretical analysis.

A characterization theorem for t-representable n-dimensional triangular norms

n-dimensional fuzzy sets are an extension of fuzzy sets that includes interval-valued fuzzy sets and interval-valued Atanassov intuitionistic fuzzy sets. The membership values of n-dimensional fuzzy sets are n-tuples of real numbers in the unit interval [0,1], called n-dimensional intervals, ordered in increasing order. The main idea in n-dimensional fuzzy sets is to consider several uncertainty levels in the memberships degrees. Triangular norms have played an important role in fuzzy sets theory, in the narrow as in the broad sense. So it is reasonable to extend this fundamental notion for n-dimensional intervals. In interval-valued fuzzy theory, interval-valued t-norms are related with t-norms via the notion of t-representability. A characterization of t-representable interval-valued t-norms is given in term of inclusion monotonicity. In this paper we generalize the notion of t-representability for n-dimensional t-norms and provide a characterization theorem for that class of n-dimensional t-norms. © 2011 Springer-Verlag Berlin Heidelberg.

Preservation of confucian values in early childhood education : a study of experts’ and educators’ views

Confucian values form the core of the Chinese culture, penetrating all levels of social life, and also set the standards for family, community and political behavior. The teaching of values is deemed to be an important aspect of young children’s education and usually the responsibility for this is seen to rest with the family. Much interest has been generated recently on the teaching of core values in early childhood curriculum in order to encourage tolerance, acceptance, trust, openness, and honesty in children. Research on Confucianism is popularly conducted in different cultural contexts all over the world. Furthermore research has shown that Confucianism continues to exert a major influence on the everyday lives of Asian communities. Given the interest in Confucian values, this research study was designed to examine the expressed views of three cohorts of professionals in Hong Kong about the preservation of such values and their application to early childhood teaching. This study confirmed the view that there is a need to preserve cultural values to enable the child to be accepted in the society, especially with the value of ‘Ren’ helping one to learn how to interact with others and with the value of ‘Li’ further defining the appropriate behaviour in this interaction.

Effectiveness of alternative organic solvents in field preservation of whole barnacles for PCR analyses

There are few reports of non-cryogenic preservation methods for marine invertebrates, so potable alcohol and acetone-based nail varnish remover (NVR) are for the first time evaluated against absolute ethanol as short-term preservatives of whole barnacles. Performance of ethanol and NVR-preserved material was comparable, but potable alcohol was significantly worse. These results are of practical importance for fieldwork in remote areas where laboratory chemicals are unattainable but potable alcohol or NVR are locally available. Of these, acetone-based NVR would be the solvent of preference.

Preservation and assemblage characteristics of some ornate Lower Devonian Ostracoda from the Humevale Siltstone and Woori Yallock Formation, southeastern Australia

.The Humevale Siltstone (late Silurian to Early Devonian, Gorstian to Pragian) and Woori Yallock Formation (Early Devonian, Emsian) of central Victoria, Australia, contain rich invertebrate fossil faunas including Ostracoda. Eight ostracod taxa are recognized and illustrated herein: Velibeyrichia wooriyallockensis (Chapman), Velibeyrichia (s.l.) australiae (Chapman), Velibeyrichia sp. 1, Velibeyrichia sp. 2, Beyrichia? ligatura (Chapman), Ulrichia sp., Euglyphella sp. and Strepulites sp. The ostracods are preserved in siltstones and mudstones as natural moulds. Ostracod assemblages are mainly shallow marine and likely include moderate- to low-energy biocoenoses, pseudo-biocoenoses (gravity flow accumulations) and thanatocoenoses.