Connectivity, online social capital, and mood : a Bayesian nonparametric analysis

Social capital indicative of community interaction and support is intrinsically linked to mental health. Increasing online presence is now the norm. Whilst social capital and its impact on social networks has been examined, its underlying connection to emotional response such as mood, has not been investigated. This paper studies this phenomena, revisiting the concept of “online social capital†in social media communities using measurable aspects of social participation and social support. We establish the link between online capital derived from social media and mood, demonstrating results for different cohorts of social capital and social connectivity. We use novel Bayesian nonparametric factor analysis to extract the shared and individual factors in mood transition across groups of users of different levels of connectivity, quantifying patterns and degree of mood transitions. Using more than 1.6 million users from Live Journal, we show quantitatively that groups with lower social capital have fewer positive moods and more negative moods, than groups with higher social capital. We show similar effects in mood transitions. We establish a framework of how social media can be used as a barometer for mood. The significance lies in the importance of online social capital to mental well-being in overall. In establishing the link between mood and social capital in online communities, this work may suggest the foundation of new systems to monitor online mental well-being.

Credit cycle dependent spread determinants in emerging sovereign debt markets

We address credit cycle dependent sovereign credit risk determinants. In our model, the spread determinants' magnitude is conditional on an unobservable endogenous sovereign credit cycle as represented by the underlying state of a Markov regime switching process. Our explanatory variables are motivated in the tradition of structural credit risk models and include changes in asset prices, interest rates, implied market volatility, gold price changes and foreign exchange rates. We examine daily frequency variations of U.S. dollar denominated Eurobond credit spreads of four major Latin American sovereign bond issuers (Brazil, Colombia, Mexico and Venezuela) with liquid bond markets during March 2000 to June 2011. We find that spread determinants are statistically significant and consistent with theory, while their magnitude remarkably varies with the state of the credit cycle. Crisis states are characterized by high spread change uncertainty and high sensitivities with respect to the spread change determinants. We further document that not only changes of local currencies, but also changes of the Euro with respect to the U.S. dollar are significant spread drivers and argue that this is consistent with the sovereigns' ability to pay.

Attributable risk analysis reveals potential healthcare savings from increased consumption of dairy products.

With rising burdens of obesity and chronic disease, the role of diet as a modifiable risk factor is of increasing public health interest. There is a growing body of evidence that low consumption of dairy products is associated with elevated risk of chronic metabolic and cardiovascular disorders. Surveys also suggest that dairy product consumption falls well below recommended targets for much of the population in many countries, including the USA, UK, and Australia. We reviewed the scientific literature on the health effects of dairy product consumption (both positive and negative) and used the best available evidence to estimate the direct healthcare expenditure and burden of disease [disability-adjusted life years (DALY)] attributable to low consumption of dairy products in Australia. We implemented a novel technique for estimating population attributable risk developed for application in nutrition and other areas in which exposure to risk is a continuous variable. We found that in the 2010-2011 financial year, AUD$2.0 billion (USD$2.1 billion, €1.6 billion, or ∼1.7% of direct healthcare expenditure) and the loss of 75,012 DALY were attributable to low dairy product consumption. In sensitivity analyses, varying core assumptions yielded corresponding estimates of AUD$1.1-3.8 billion (0.9-3.3%) and 38,299-151,061 DALY lost. The estimated healthcare cost attributable to low dairy product consumption is comparable with total spending on public health in Australia (AUD$2.0 billion in 2009-2010). These findings justify the development and evaluation of cost-effective interventions that use dairy products as a vector for reducing the costs of diet-related disease.

The microbiological and sustainability effects of washing anaesthesia breathing circuits less frequently

In the presence of single-use airway filters, we quantified anaesthetic circuit aerobic microbial contamination rates when changed every 24 h, 48 h and 7 days. Microbiological samples were taken from the interior of 305 anaesthetic breathing circuits over a 15-month period (3197 operations). There was no significant difference in the proportion of contaminated circuits when changed every 24 h (57/105 (54%, 95% CI 45–64%)) compared with 48 h (43/100 (43%, 95% CI 33–53%, p = 0.12)) and up to 7 days (46/100 (46%, 95% CI 36–56%, p = 0.26)). Median bacterial counts were not increased at 48 h or 7 days provided circuits were routinely emptied of condensate. Annual savings for one hospital (six operating theatres) were $AU 5219 (£3079, €3654, $US 4846) and a 57% decrease in anaesthesia circuit steriliser loads associated with a yearly saving of 2760 kWh of electricity and 48 000 l of water. Our findings suggest that extended circuit use from 24 h up to 7 days does not significantly increase bacterial contamination, and is associated with labour, energy, water and financial savings.

Everyday multiculturalism: Catching the bus in Darwin, Australia

Following acts of violence in major cities, the future of multiculturalism as a philosophy and a state-sponsored policy to promote peace and interdependence in white majority societies seem uncertain. Ethnographic research that explores the lived experience of multiculturalism in shared public spaces, however, offers the possibility to explore emotional stress as well as possibilities for change in culturally diverse cities. Within this literature, however, there is little grounded research that explores Indigenous-ethnic minority relationships. This paper foregrounds and describes a seemingly mundane event such as catching a bus that entangles my body with an Aboriginal woman and a migrant woman from Fiji in Darwin, Australia. The paper demonstrates how injury, anger, shame and discomfort unfolds when bodies of colour are sites of stress. I explore the emergence of this bodily stress that has outcomes for the capacity of racially differentiated bodies of colour to respond ethically in encounters with strangers. I argue that thick descriptions of events, conceptualisations of agency as distributed and broader understandings of the social have the potential to contribute to anti-racist agendas in Euro-colonial societies with separate Indigenous and multicultural policy frameworks in ways that do not require bodies to 'accumulate' or 'inhabit' whiteness. © 2014 © 2014 Taylor & Francis.

Young people, pleasure, and the normalization of pornography: sexual health and well-being in a time of proliferation?

It has been argued that pornography is the most prominent sex educator for young people today (Flood, M. (2010). Young men using pornography. In E. Boyle (Ed.), Everyday Pornography (pp. 164–178). Oxford: Routledge). Research indicates that first exposure to pornography can be as young as 11 years of age. There is evidence that exposure to pornography is shaping young people’s sexual expectations and practices (H€aggstro ̈ m-Nordin et al. 2005). Many young people are learning what sex looks like from what they – or their partner or peers – observe in pornography. Significantly,pornography is normalizing sex acts that most women do not enjoy and may experience as degrading, painful, or violating. This raises serious implications for young people’s capacity to develop a sexuality that incorporates mutual pleasure, respect, and negotiation of free and full consent.While the results are complex and nuanced, research into the effects of pornography consumption provides reliable evidence that exposure to pornography increases aggressive attitudes and behavior towards women for some viewers (Malamuth et al. Annual Review of Sex Research 11, 26–91, 2000). Pornography consumption also has been found to be associated with sexual health risk taking and can impact negatively on body image and sense of self (Dean, L. (2007). Young Men, Pornography and Sexual Health Promotion, MA Research, Brighton University, Brighton, in possession of the author), and as such is a serious health and well-being issue, particularly for young women.This chapter explores preservice teachers’ reactions to pornography education using two examples from teaching of an elective Teaching Sexuality in the Middle Years, in 2011. These examples explore the complex emotions such teaching can generate and the challenges faced by preservice teachers when they are encouraged to confront the gendered and violent consequences of the normalization of pornography in a coeducational setting.

Heterogeneity of miR-10b expression in circulating tumor cells

Circulating tumor cells (CTCs) in the blood of cancer patients are recognized as important potential targets for future anticancer therapies. As mediators of metastatic spread, CTCs are also promising to be used as € liquid biopsyto aid clinical decision-making. Recent work has revealed potentially important genotypic and phenotypic heterogeneity within CTC populations, even within the same patient. MicroRNAs (miRNAs) are key regulators of gene expression and have emerged as potentially important diagnostic markers and targets for anti-cancer therapy. Here, we describe a robust in situ hybridization (ISH) protocol, incorporating the CellSearch ® CTC detection system, enabling clinical investigation of important miRNAs, such as miR-10b on a cell by cell basis. We also use this method to demonstrate heterogeneity of such as miR-10b on a cell-by-cell basis. We also use this method to demonstrate heterogeneity of miR-10b in individual CTCs from breast, prostate and colorectal cancer patients.