46 resultados para Visualization Of Interval Methods
Filtro por publicador
- Acceda, el repositorio institucional de la Universidad de Las Palmas de Gran Canaria. España (3)
- AMS Tesi di Dottorato - Alm@DL - Università di Bologna (8)
- AMS Tesi di Laurea - Alm@DL - Università di Bologna (1)
- Aquatic Commons (23)
- ARCA - Repositório Institucional da FIOCRUZ (1)
- ArchiMeD - Elektronische Publikationen der Universität Mainz - Alemanha (2)
- Archive of European Integration (8)
- Archivo Digital para la Docencia y la Investigación - Repositorio Institucional de la Universidad del País Vasco (4)
- Aston University Research Archive (28)
- Biblioteca de Teses e Dissertações da USP (1)
- Biblioteca Digital da Produção Intelectual da Universidade de São Paulo (19)
- Biblioteca Digital da Produção Intelectual da Universidade de São Paulo (BDPI/USP) (11)
- Biodiversity Heritage Library, United States (2)
- BORIS: Bern Open Repository and Information System - Berna - Suiça (95)
- Brock University, Canada (2)
- Bucknell University Digital Commons - Pensilvania - USA (3)
- Bulgarian Digital Mathematics Library at IMI-BAS (15)
- CaltechTHESIS (4)
- Cambridge University Engineering Department Publications Database (42)
- CentAUR: Central Archive University of Reading - UK (46)
- Central European University - Research Support Scheme (1)
- Chinese Academy of Sciences Institutional Repositories Grid Portal (24)
- Cochin University of Science & Technology (CUSAT), India (2)
- Collection Of Biostatistics Research Archive (1)
- Comissão Econômica para a América Latina e o Caribe (CEPAL) (4)
- CORA - Cork Open Research Archive - University College Cork - Ireland (2)
- Corvinus Research Archive - The institutional repository for the Corvinus University of Budapest (5)
- CUNY Academic Works (1)
- Dalarna University College Electronic Archive (7)
- Deakin Research Online - Australia (50)
- Department of Computer Science E-Repository - King's College London, Strand, London (1)
- DI-fusion - The institutional repository of Université Libre de Bruxelles (1)
- Digital Commons - Michigan Tech (4)
- Digital Commons @ DU | University of Denver Research (1)
- Digital Commons at Florida International University (7)
- Digital Repository at Iowa State University (1)
- DigitalCommons@The Texas Medical Center (17)
- DRUM (Digital Repository at the University of Maryland) (1)
- Duke University (11)
- eResearch Archive - Queensland Department of Agriculture; Fisheries and Forestry (4)
- Greenwich Academic Literature Archive - UK (1)
- Harvard University (1)
- Helda - Digital Repository of University of Helsinki (12)
- Illinois Digital Environment for Access to Learning and Scholarship Repository (1)
- Indian Institute of Science - Bangalore - Índia (32)
- Instituto Nacional de Saúde de Portugal (1)
- Instituto Politécnico do Porto, Portugal (9)
- Instituto Superior de Psicologia Aplicada - Lisboa (1)
- Martin Luther Universitat Halle Wittenberg, Germany (1)
- Massachusetts Institute of Technology (2)
- Memoria Académica - FaHCE, UNLP - Argentina (3)
- National Center for Biotechnology Information - NCBI (18)
- Nottingham eTheses (1)
- Open University Netherlands (1)
- Plymouth Marine Science Electronic Archive (PlyMSEA) (8)
- Publishing Network for Geoscientific & Environmental Data (4)
- QSpace: Queen's University - Canada (1)
- QUB Research Portal - Research Directory and Institutional Repository for Queen's University Belfast (61)
- Queensland University of Technology - ePrints Archive (67)
- ReCiL - Repositório Científico Lusófona - Grupo Lusófona, Portugal (1)
- Repositório Alice (Acesso Livre à Informação Científica da Embrapa / Repository Open Access to Scientific Information from Embrapa) (2)
- Repositório digital da Fundação Getúlio Vargas - FGV (3)
- Repositório Digital da UNIVERSIDADE DA MADEIRA - Portugal (2)
- Repositório do Centro Hospitalar de Lisboa Central, EPE - Centro Hospitalar de Lisboa Central, EPE, Portugal (1)
- Repositório Institucional da Universidade de Aveiro - Portugal (3)
- Repositório Institucional da Universidade de Brasília (1)
- Repositório Institucional dos Hospitais da Universidade Coimbra (1)
- Repositório Institucional UNESP - Universidade Estadual Paulista "Julio de Mesquita Filho" (109)
- Repositorio Institucional Universidad EAFIT - Medelin - Colombia (1)
- RUN (Repositório da Universidade Nova de Lisboa) - FCT (Faculdade de Cienecias e Technologia), Universidade Nova de Lisboa (UNL), Portugal (3)
- SAPIENTIA - Universidade do Algarve - Portugal (1)
- School of Medicine, Washington University, United States (4)
- Universidad de Alicante (6)
- Universidad del Rosario, Colombia (1)
- Universidad Politécnica de Madrid (21)
- Universidade Federal do Pará (1)
- Universita di Parma (1)
- Universitat de Girona, Spain (6)
- Universitätsbibliothek Kassel, Universität Kassel, Germany (5)
- Université de Lausanne, Switzerland (2)
- Université de Montréal (1)
- Université de Montréal, Canada (3)
- University of Connecticut - USA (2)
- University of Michigan (53)
- University of Queensland eSpace - Australia (19)
- University of Southampton, United Kingdom (1)
- University of Washington (1)
- WestminsterResearch - UK (4)
- Worcester Research and Publications - Worcester Research and Publications - UK (2)
Resumo:
Intracellular reactive oxygen species (ROS) production is essential to normal cell function. However, excessive ROS production causes oxidative damage and cell death. Many pharmacological compounds exert their effects on cell cycle progression by changing intracellular redox state and in many cases cause oxidative damage leading to drug cytotoxicity. Appropriate measurement of intracellular ROS levels during cell cycle progression is therefore crucial in understanding redox-regulation of cell function and drug toxicity and for the development of new drugs. However, due to the extremely short half-life of ROS, measuring the changes in intracellular ROS levels during a particular phase of cell cycle for drug intervention can be challenging. In this article, we have provided updated information on the rationale, the applications, the advantages and limitations of common methods for screening drug effects on intracellular ROS production linked to cell cycle study. Our aim is to facilitate biomedical scientists and researchers in the pharmaceutical industry in choosing or developing specific experimental regimens to suit their research needs.