16 resultados para Prognostic Marker
Filtro por publicador
- Aberdeen University (1)
- Acceda, el repositorio institucional de la Universidad de Las Palmas de Gran Canaria. España (1)
- AMS Tesi di Dottorato - Alm@DL - Università di Bologna (25)
- AMS Tesi di Laurea - Alm@DL - Università di Bologna (2)
- Aquatic Commons (2)
- ArchiMeD - Elektronische Publikationen der Universität Mainz - Alemanha (2)
- Archive of European Integration (1)
- Archivo Digital para la Docencia y la Investigación - Repositorio Institucional de la Universidad del País Vasco (2)
- Aston University Research Archive (2)
- Biblioteca de Teses e Dissertações da USP (1)
- Biblioteca Digital da Produção Intelectual da Universidade de São Paulo (47)
- Biblioteca Digital da Produção Intelectual da Universidade de São Paulo (BDPI/USP) (5)
- Biblioteca Digital de Teses e Dissertações Eletrônicas da UERJ (1)
- BORIS: Bern Open Repository and Information System - Berna - Suiça (241)
- Cambridge University Engineering Department Publications Database (3)
- CentAUR: Central Archive University of Reading - UK (16)
- Chinese Academy of Sciences Institutional Repositories Grid Portal (24)
- Cochin University of Science & Technology (CUSAT), India (1)
- Collection Of Biostatistics Research Archive (1)
- CORA - Cork Open Research Archive - University College Cork - Ireland (1)
- Dalarna University College Electronic Archive (2)
- Deakin Research Online - Australia (31)
- DI-fusion - The institutional repository of Université Libre de Bruxelles (2)
- Digital Commons - Michigan Tech (1)
- Digital Peer Publishing (2)
- DigitalCommons@The Texas Medical Center (27)
- Doria (National Library of Finland DSpace Services) - National Library of Finland, Finland (2)
- Duke University (3)
- eResearch Archive - Queensland Department of Agriculture; Fisheries and Forestry (11)
- Glasgow Theses Service (1)
- Greenwich Academic Literature Archive - UK (1)
- Helda - Digital Repository of University of Helsinki (34)
- Indian Institute of Science - Bangalore - Índia (13)
- Instituto Politécnico de Viseu (1)
- Instituto Politécnico do Porto, Portugal (1)
- Lume - Repositório Digital da Universidade Federal do Rio Grande do Sul (1)
- National Center for Biotechnology Information - NCBI (20)
- Plymouth Marine Science Electronic Archive (PlyMSEA) (7)
- Publishing Network for Geoscientific & Environmental Data (35)
- QUB Research Portal - Research Directory and Institutional Repository for Queen's University Belfast (138)
- Queensland University of Technology - ePrints Archive (96)
- Repositório Institucional UNESP - Universidade Estadual Paulista "Julio de Mesquita Filho" (116)
- RUN (Repositório da Universidade Nova de Lisboa) - FCT (Faculdade de Cienecias e Technologia), Universidade Nova de Lisboa (UNL), Portugal (2)
- School of Medicine, Washington University, United States (3)
- Scientific Open-access Literature Archive and Repository (2)
- Universidad de Alicante (2)
- Universidad del Rosario, Colombia (5)
- Universidad Politécnica de Madrid (4)
- Universidade de Lisboa - Repositório Aberto (2)
- Universidade Federal do Pará (1)
- Universidade Federal do Rio Grande do Norte (UFRN) (2)
- Universitat de Girona, Spain (1)
- Université de Lausanne, Switzerland (10)
- Université de Montréal, Canada (5)
- Université Laval Mémoires et thèses électroniques (1)
- University of Connecticut - USA (2)
- University of Queensland eSpace - Australia (8)
Resumo:
MS-based proteomic methods were utilised for the first time in the discovery of novel penile cancer biomarkers. MALDI MS imaging was used to obtain the in situ biomolecular MS profile of squamous cell carcinoma of the penis which was then compared to benign epithelial MS profiles. Spectra from cancerous and benign tissue areas were examined to identify MS peaks that best distinguished normal epithelial cells from invasive squamous epithelial cells, providing crucial evidence to suggest S100A4 to be differentially expressed. Verification by immunohistochemistry resulted in positive staining for S100A4 in a sub-population of invasive but not benign epithelial cells.