Elucidación de conceptos aplicados a la organización y cultura organizacional

La sociedad ha definido ciertas normas y pautas de comportamiento en los individuos que se encuentran en ella. La interacción y red de relaciones dadas entre ellos constituye la identidad de la misma. El carácter de las sociedades está determinado por medio de la Institución Social la cual proporciona una interpretación más profunda de la complejidad de las relaciones sociales de cualquier conjunto de personas relacionadas entre sí. Dentro de la sociedad existe una noción de Cultura Social que refleja una experiencia colectiva que vivencian todos los individuos en ella, los acontecimientos que han tenido lugar en el pasado y que repercuten o tienen incidencia en el presente e incluso en el futuro de ese grupo de personas. La organización resulta ser el vínculo existente entre un conjunto de individuos que se encuentran relacionados y dispuestos a alcanzar una meta común por medio del establecimiento de roles o funciones. La Cultura Organizacional genera sentido de identidad y pertenencia a la Organización, además de incentivar el compromiso entre los integrantes de la misma para la consecución de logros y objetivos en común. Por tanto, la Cultura Social no debe ser aplicada de igual forma a la Cultura Organizacional, ya que la vinculación y la clase de relación que surge de los individuos en la Sociedad o en la Organización, es completamente diferente. Los valores, creencias y ritos, que se crean en la sociedad no pueden ser transferidos a una empresa debido a que las relaciones y el fin último de cada una de ellas es diferente.

Análisis de las formas de apropiación nocturna del espacio público, en el parque de los hippies, localidad de chapinero, a partir de una muestra poblacional de jóvenes entre 18-­‐28 años, a la luz de los parámetros de Enric Pol y Tomeur Vidal sobre la “apropiación” del espacio

El interés de este estudio de caso es comprender y explicar la apropiación del espacio público urbano no sólo como un vínculo cotidiano entre el territorio y sus ciudadanos, sino, además, como un proceso dialéctico que, genera significado, identidad y apego al lugar. En este sentido se analizan las formas de apropiación nocturnas del Parque de los Hippies a partir de una muestra poblacional de jóvenes entre 18-28 años, a la luz de los parámetros de Enric Pol y Tomeu Vidal. Evidenciando que desde un acercamiento cotidiano a la realidad urbana, que reconozca la significación histórica, social, cultural y económica de los territorios, así como las dinámicas de convivencia y conflictos que se presentan en dichos espacios, se puede, desde el enfoque de gestión y desarrollo urbanos, generar recomendaciones para movilizar acciones que resalten y preserven los valores urbanos multidimensionales del lugar; fortalezcan algunas de sus formas de apropiación y, promuevan la convivencia entre las distintas formas y sus actores.

Annotation and characterization of the Plasmodium vivax rhoptry neck protein 4 (PvRON4)

Background: The tight junction (TJ) is one of the most important structures established during merozoite invasion of host cells and a large amount of proteins stored in Toxoplasma and Plasmodium parasites’ apical organelles are involved in forming the TJ. Plasmodium falciparum and Toxoplasma gondii apical membrane antigen 1 (AMA-1) and rhoptry neck proteins (RONs) are the two main TJ components. It has been shown that RON4 plays an essential role during merozoite and sporozoite invasion to target cells. This study has focused on characterizing a novel Plasmodium vivax rhoptry protein, RON4, which is homologous to PfRON4 and PkRON4. Methods: The ron4 gene was re-annotated in the P. vivax genome using various bioinformatics tools and taking PfRON4 and PkRON4 amino acid sequences as templates. Gene synteny, as well as identity and similarity values between open reading frames (ORFs) belonging to the three species were assessed. The gene transcription of pvron4, and the expression and localization of the encoded protein were also determined in the VCG-1 strain by molecular and immunological studies. Nucleotide and amino acid sequences obtained for pvron4 in VCG-1 were compared to those from strains coming from different geographical areas. Results: PvRON4 is a 733 amino acid long protein, which is encoded by three exons, having similar transcription and translation patterns to those reported for its homologue, PfRON4. Sequencing PvRON4 from the VCG-1 strain and comparing it to P. vivax strains from different geographical locations has shown two conserved regions separated by a low complexity variable region, possibly acting as a “smokescreen”. PvRON4 contains a predicted signal sequence, a coiled-coil α-helical motif, two tandem repeats and six conserved cysteines towards the carboxyterminus and is a soluble protein lacking predicted transmembranal domains or a GPI anchor. Indirect immunofluorescence assays have shown that PvRON4 is expressed at the apical end of schizonts and co-localizes at the rhoptry neck with PvRON2.

PvRON2, a new Plasmodium vivax rhoptry neck antigen

Background: Rhoptries are specialized organelles from parasites belonging to the phylum Apicomplexa; they secrete their protein content during invasion of host target cells and are sorted into discrete subcompartments within rhoptry neck or bulb. This distribution is associated with these proteins’ role in tight junction (TJ) and parasitophorous vacuole (PV) formation, respectively. Methods: Plasmodium falciparum RON2 amino acid sequence was used as bait for screening the codifying gene for the homologous protein in the Plasmodium vivax genome. Gene synteny, as well as identity and similarity values, were determined for ron2 and its flanking genes among P. falciparum, P. vivax and other malarial parasite genomes available at PlasmoDB and Sanger Institute databases. Pvron2 gene transcription was determined by RT-PCR of cDNA obtained from the P. vivax VCG-1 strain. Protein expression and localization were assessed by Western blot and immunofluorescence using polyclonal anti-PvRON2 antibodies. Co-localization was confirmed using antibodies directed towards specific microneme and rhoptry neck proteins. Results and discussion: The first P. vivax rhoptry neck protein (named here PvRON2) has been identified in this study. PvRON2 is a 2,204 residue-long protein encoded by a single 6,615 bp exon containing a hydrophobic signal sequence towards the amino-terminus, a transmembrane domain towards the carboxy-terminus and two coiled coil a-helical motifs; these are characteristic features of several previously described vaccine candidates against malaria. This protein also contains two tandem repeats within the interspecies variable sequence possibly involved in evading a host’s immune system. PvRON2 is expressed in late schizonts and localized in rhoptry necks similar to what has been reported for PfRON2, which suggests its participation during target cell invasion. Conclusions: The identification and partial characterization of the first P. vivax rhoptry neck protein are described in the present study. This protein is homologous to PfRON2 which has previously been shown to be associated with PfAMA-1, suggesting a similar role for PvRON2.

Decoding the canada's foreing and security policy: tracking the strategic and ethicliberal approaches of a middle power's behavior

The article attempts to explain the main paradox faced by Canada at formulating its foreign policy on international security. Explained in economic and political terms, this paradox consists in the contradiction between the Canadian ability to achieve its strategic goals, serving to its own national interest and its dependence on the United States. The first section outlines three representative examples to evaluate this paradox: the Canada’s position in North American security regime, the US-Canada economic security relations, and the universe of possibilities for action of Canada as a middle power. The second section suggests that liberal agenda, especially concerning to ethical issues, has been established by this country to minimize this paradox. By pursing this agenda, Canada is able to reaffirm its national identity and therefore its independence on the United States. The third section evaluates both the explained paradox and the reaffirmation of Canadian identity during the Jean Chrétien (1993-2003), Paul Martin (2003-2006) and Stephen Harper’s (2006) governments.

Executive functions in school-aged children: age and socioeconomic status effects

Lately, the study of prefrontal executive functions in grade scholars has noticeably increased. The aim of this study is to investigate the influence of age and socioeconomic status (sEs) on executive tasks performance and to analyze those socioeconomic variables that predict a better execution. A sample of 254 children aged between 7 and 12 years from the city of santa Fe, Argentina and belonging to different socioeconomic status were tested. A bat- tery of executive functions sensitive to prefrontal function was used to obtain the results. These in- dicate a significant influence of age and SES on executive functions. The cognitive patterns follow a different path according to the development and sEs effect. Besides, it is revealed a pattern of low cognitive functioning in low-sEs children in all executive functions. Finally, from the variables included in this study, it was found that only the educational level of the mother and the housing conditions are associated to the children’s executive function. The results are discussed in terms of the influence of the cerebral maturation and the envi- ronmental variables in the executive functioning.

Solid waste management in metropolitan areas: barriers and opportunities for intermunicipal arrangements in Brazil

Municipal solid waste issue has acquired a growing importance into urban management discussions, particularly in metropolitan areas. Although metropolitan regions were created for integrating public functions of common interest, it appears that the structures, in general, are limited to planning  activities. In this context, the democratization process occurred in Brazil during 1980’s led to the  strengthening of inter-municipal arrangements of voluntary cooperation, acquiring great expressiveness  in metropolitan areas, responsible for 60% of waste generated in Brazil. However, despite the  consortia emergence as an alternative management of metropolitan territory, its process of setting up and operation is not free of challenges and dilemmas. This paper starts with the hypothesis that  inter-municipal consortia in metropolitan areas have high strength asymmetry and weak regional  identity among municipalities, conditions that tend to create barriers to its concretization. In this  context, this research aim  to develop a comparative study of inter-municipal arrangements for solid  waste management in the metropolitan areas of Curitiba (pr), Belo Horizonte (bh) and Salvador  (ba), by identifying influence degree of regional identity and strength asymmetry in these arrangements. The multiple case study reveals an inverse proportionality relationship between regional  identity and strength asymmetry among the municipalities, deeply influenced by political interinstitutional  arrangement and the metropolitan area in which they are is inserted.

Perspectiva ético-política del ser ciudadano: una mirada desde los jóvenes

Este artículo se deriva de la investigación "Referentes ético-políticos de la ciudadaníade un grupo de jóvenes de la ciudad de Manizales", la cual indagó por las perspectivas éticas y políticas implícitas en la ciudadanía según jóvenes universitarios estudiantes de ciencia política y jóvenes pertenecientes a la cultura urbana de hip-hop. La pregunta de investigación se fundamentó en los planteamientos de Rawls sobre ciudadanía y justicia, de Taylor sobre autenticidad y de Kymlicka sobre ciudadanía multicultural y derechos diferenciados. Los antecedentes investigativos revisados parecen orientarse a la indagación por los implícitos morales y políticos de la ciudadanía, la noción de ciudadanía en el marco de una idea de democracia, la ciudadanía y la participación juvenil y la ciudadanía y la construcción de identidad. Se encontró que los dos grupos hacen referencia a la libertad, la igual dignidad, la responsabilidad, el respeto, la solidaridad, y la tolerancia, como los principios fundamentales de la ciudadanía. Llamó la atención que, mientras para los jóvenes universitarios la ciudadanía se debe instaurar como un estatus socio-político —que permita exigir los derechos de manera individual—, para los jóvenes hip-hoperos la ciudadanía se debe asumir a partir del reconocimiento de los marcos socio-culturales que le dan sentido de vida y pertenencia a esta cultura juvenil urbana.-----This article derives from the research entitled "Ethical-political Citizenship Reference Points from a Group of Young People from the City of Manizales", which sought to discover the ethical and political perspectives implied by citizenship according to young political science university students and youngsters belonging to the urban Hip-Hop culture. The aim of the investigation is based on Rawls’ proposals regarding citizenship and justice, Taylor’s on authenticity, and Kymlicka’s on multicultural citizens and group-differentiated rights. Revised research references appear to be oriented towards indignation due to citizenship-implied morals and politics, the notion of citizenship within the framework of an idea of democracy, citizenship and youth participation, and citizenship and the building of identity. It was discovered that both groups made reference to freedom, equal dignity, responsibility, respect, solidarity and tolerance as the basic fundamentals of citizenship. It was interesting to see that, while for university students citizenship should be established as a socio-political status —allowing to demand rights on an individual basis—, for the young Hip-Hoppers citizenship should be assumed from the basis of acknowledgement of the existence of socio-cultural frameworks that provide this young urban culture with a sense of life and belonging.