Demand of children in Colombia : guessing or planning

El artículo analiza los determinantes de la presencia de hijos no deseados en Colombia. Se utiliza la información de la Encuesta Nacional de Demografía y Salud (ENDS, 2005), específicamente para las mujeres de 40 años o más. Dadas las características especiales de la variable que se analiza, se utilizan modelos de conteo para verificar si determinadas características socioeconómicas como la educación o el estrato económico explican la presencia de hijos no deseados. Se encuentra que la educación de la mujer y el área de residencia son determinantes significativos de los nacimientos no planeados. Además, la relación negativa entre el número de hijos no deseados y la educación de la mujer arroja implicaciones clave en materia de política social.

Validez y confiabilidad, versión hispana Instrumento de Tamizaje Juvenil

Objetivos: evaluar la validez y confiabilidad de la versión hispana del instrumento de Tamizaje Juvenil (Encuesta de Salud Juvenil, ESJ) de la Universidad de Columbia aplicados en 2009 por el Programa de Salud Mental Juvenil de la Universidad del Rosario (UR) en el 8avo grado del Centro Educativo Integral de Colsubsidio (CEIC) en Bogotá, Colombia Metodología: Diseño observacional de evaluación de prueba diagnóstica tipo tamizaje en las dos etapas consecutivas del Programa de Tamizaje Juvenil aplicado en 183 alumnos. Evaluación de la reproducibilidad de las pruebas aplicadas a una sub muestra de 63 alumnos calculado con un muestreo aleatorizado por afijacion proporcional en un intervalo de 20 días. Resultados: el instrumento Encuesta de Salud Juvenil (ESJ) mostró una alta sensibilidad (100 %) y adecuada especificidad (89,09 %), un valor predictivo positivo del 85,88 % lo que le confiere adecuada validez. La confiabilidad y consistencia interna de la prueba son buenas, Alfa de Cronbach: 0,700, así como la concordancia de la ESJ inicial y la entrevista clínica de la segunda etapa del tamizaje (Kappa de 0.867, error estándar de 0.037 (p<0.001)). La reproducibilidad mostró un índice de Kappa de 0,645 en la sub muestra evaluada 20 días después. Conclusiones: la versión hispana del instrumento de Tamizaje Juvenil de la Universidad de Columbia tiene validez y confiabilidad adecuada para la detección de conducta suicida y signos de enfermedad mental en adolescentes.

Liderazgo y resiliencia: una revisión de la literatura.

La resiliencia se plantea como aquel factor que permite que los individuos se sobrepongan eficazmente frente a los cambios constantes del entorno, siendo un gran foco de atención del estudio de las organizaciones y su desempeño en el mercado actual. Lo valioso en esta dinámica, es la revisión del término desde una perspectiva de cambio, en donde lo indispensable no es limitarse a superar las disrupciones y crisis presentadas, si no que desde las ciencias sociales se logre ir más allá, tomando este dinamismo como una oportunidad de crecimiento. De igual forma se presenta el liderazgo como aquel atributo que fortalece el desarrollo de la resiliencia en el quehacer diario, logrando con su influencia el bienestar y calidad de vida de los colaboradores, como fin único de su aplicación.

MicroRNA-3148 Modulates Allelic Expression of Toll-Like Receptor 7 Variant Associated with Systemic Lupus Erythematosus

We previously reported that the G allele of rs3853839 at 3′untranslated region (UTR) of Toll-like receptor 7 (TLR7) was associated with elevated transcript expression and increased risk for systemic lupus erythematosus (SLE) in 9,274 Eastern Asians [P = 6.5×10−10, odds ratio (OR) (95%CI) = 1.27 (1.17–1.36)]. Here, we conducted trans-ancestral fine-mapping in 13,339 subjects including European Americans, African Americans, and Amerindian/Hispanics and confirmed rs3853839 as the only variant within the TLR7-TLR8 region exhibiting consistent and independent association with SLE (Pmeta = 7.5×10−11, OR = 1.24 [1.18–1.34]). The risk G allele was associated with significantly increased levels of TLR7 mRNA and protein in peripheral blood mononuclear cells (PBMCs) and elevated luciferase activity of reporter gene in transfected cells. TLR7 3′UTR sequence bearing the non-risk C allele of rs3853839 matches a predicted binding site of microRNA-3148 (miR-3148), suggesting that this microRNA may regulate TLR7 expression. Indeed, miR-3148 levels were inversely correlated with TLR7 transcript levels in PBMCs from SLE patients and controls (R2 = 0.255, P = 0.001). Overexpression of miR-3148 in HEK-293 cells led to significant dose-dependent decrease in luciferase activity for construct driven by TLR7 3′UTR segment bearing the C allele (P = 0.0003). Compared with the G-allele construct, the C-allele construct showed greater than two-fold reduction of luciferase activity in the presence of miR-3148. Reduced modulation by miR-3148 conferred slower degradation of the risk G-allele containing TLR7 transcripts, resulting in elevated levels of gene products. These data establish rs3853839 of TLR7 as a shared risk variant of SLE in 22,613 subjects of Asian, EA, AA, and Amerindian/Hispanic ancestries (Pmeta = 2.0×10−19, OR = 1.25 [1.20–1.32]), which confers allelic effect on transcript turnover via differential binding to the epigenetic factor miR-3148.

Analysis of the employee’s labor agreement suspension in Colombia and some legislation references

Considering that the employment contract suspension responds to labor stability,one of the most important principles of labor law is important to study it because itsprincipal purpose is to maintain the link between de employer and the employeedespite the presence of adversity or other situations that would break up the relationshipin other fields. However, at the occurrence of any of the grounds of suspensionmay be presented some questions or voids that it will try to be answer in this paper.Consequently we shall refer first to the definition, purpose and characteristics of thesuspension. Subsequently, will be analyzed in detail every single ground of contractsuspension in Colombia. Then, will be studied the effects of the suspension andwe will refer to the resumption of work, and conclude with the comparative analysisof the figure in some Hispanic countries (Mexico, Paraguay and Spain).

cultural field of the seventeenth century in Spain and New Granada

The article aims to make visible some nuances of the 17TH century in Spain and the New Granada with emphasis on articulations and tensions that made up this cultural and social space through the analysis of the letrados and its position in the Hispanic cultural field of the 16th and 17TH centuries. This article also discusses the traditional thesis about the cultural isolation and obscurantism in the American colonies before the eighteenth century through the analysis of the circulation of books and knowledge between mainland Spain and its colonies, and the heterogeneous character of the lawyers that affect the symbolic monopoly of the Catholic Church.

Validity and reliability of the international fItness scale (IFIS) in a population-based sample of schoolchildren in Bogota, Colombia: The FUPRECOL study

The International FItness Scale (IFIS) is a self-reported measure of physical fitness that could easily. This scale has been validated in children, adolescents, and young adults; however, it is unknown whether the IFIS represents a valid and reliable estimate of physical fitness in Latino-American youth population. In the present study we aimed to examine the validity and reliability of the IFIS on a population-based sample of schoolchildren in Bogota, Colombia. Participants were 1,875 Colombian youth (56.2% girls) aged 9 to 17.9 years old. We measured adiposity markers (body fat, waist-to-height ratio, skinfold thicknesses and BMI), blood pressure, lipids profile, fasting glucose, and physical fitness level (self reported and measured). Also, a validated cardiometabolic risk index was used. An age- and sex-matched sample of 229 Schoolchildren originally not included in the study sample fulfilled IFIS twice for reliability purposes. Our data suggest that both measured and self-reported overall fitness were associated inversely with adiposity indicators and a cardiometabolic risk score. Overall, schoolchildren who self-reported “good” and “very good” fitness had better measured fitness than those who reported “very poor” and “poor” fitness (all p<0.001). Test–retest reliability of IFIS items was also good, with an average weighted Kappa of 0.811. Therefore, our findings suggest that self-reported fitness, as assessed by IFIS, is a valid, reliable, and health-related measure, and it can be a good alternative for future use in large studies with Latin-schoolchildren from Colombia.