Evaluación y mejoramiento productivo de PLASPUCOL

Este proyecto de grado pretende evaluar el comportamiento productivo de la empresa Plaspucol ubicada en la ciudad de Bogotá, identificando las deficiencias en su proceso y generando mecanismo de mejoramiento a través de un previo análisis. Para ello es necesario partir de un marco teórico del plástico como lo es su historia, su evolución, clasificación y su posicionamiento e influencia económica a nivel mundial y vista a su vez desde el ámbito nacional. Para analizar dichas situaciones se usaron herramientas aprendidas en lo largo de nuestra formación profesional como los diagramas de recorrido, diagramas de flujo, diagrama hombre-máquina, diagrama de balanceo, muestreo y un moderno simulador llamado Promodel con el cual se diagnostica a la empresa identificando puntos débiles y cuellos de botella en la producción en la situación actual y se crea una situación futura con propuestas de mejora empleando éste simulador.

Genome-wide evidence for speciation with gene flow in Heliconius butterflies

Most speciation events probably occur gradually, without complete and immediate reproductive isolation, but the full extent of gene flow between diverging species has rarely been characterized on a genome-wide scale. Documenting the extent and timing of admixture between diverging species can clarify the role of geographic isolation in speciation. Here we use new methodology to quantify admixture at different stages of divergence in Heliconius butterflies, based on whole-genome sequences of 31 individuals. Comparisons between sympatric and allopatric populations of H. melpomene, H. cydno, and H. timareta revealed a genome-wide trend of increased shared variation in sympatry, indicative of pervasive interspecific gene flow. Up to 40% of 100-kb genomic windows clustered by geography rather than by species, demonstrating that a very substantial fraction of the genome has been shared between sympatric species. Analyses of genetic variation shared over different time intervals suggested that admixture between these species has continued since early in speciation. Alleles shared between species during recent time intervals displayed higher levels of linkage disequilibrium than those shared over longer time intervals, suggesting that this admixture took place at multiple points during divergence and is probably ongoing. The signal of admixture was significantly reduced around loci controlling divergent wing patterns, as well as throughout the Z chromosome, consistent with strong selection for Müllerian mimicry and with known Z-linked hybrid incompatibility. Overall these results show that species divergence can occur in the face of persistent and genome-wide admixture over long periods of time.