3 resultados para 324.9861

em Universitat de Girona, Spain


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La malaltia de Crohn és una malaltia inflamatòria intestinal crònica d'etiologia encara desconeguda. Actualment es pensa que hi participen factors genètics i immunològics que confereixen una susceptibilitat a l'hoste, i factors externs o ambientals, com serien els microorganismes i/o l'estil de vida. L'objectiu principal d'aquest treball ha estat descriure les poblacions bacterianes associades especialment als malalts de Crohn, amb la intenció d'identificar possibles agents etiològics. Els resultats d'aquest treball coincideixen amb investigacions prèvies que descriuen l'alteració bacteriana present en els malalts de Crohn (disbiosi) i recolzen la hipòtesi que implica el recentment descrit patovar "Adherent- Invasive Escherichia coli" (AIEC) en l'etiologia d'aquesta malaltia inflamatòria intestinal. A més, contribuïm a la descripció de les poblacions d'E. coli associades a la mucosa intestinal aportant dades sobre aspectes ecològics i patogènics. Finalment, descrivim nous aspectes fenotípics d'AIEC que podrien estar relacionats amb la seva patogènia, com seria la capacitat de formar biofilms.

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The objectives of the thesis are identify in the current tourism landscape, tourist typologies which are capable of ensuring an adequate level of sustainability, ie that take into account the need to establish effective partnerships between major players in the touristic sector: 1. Looking for practical examples of more responsible tourism forms with resources. 2. Stressing the role played by ecotourism, this form of tourism according to the qual makes your holiday visitors relate more directly conscious of environmental and sociocultural present in the venue. 3. identifying actions to ensure the protection of the environment and the economic take off by traditionally depressed areas. 4. identifying objects aimed at boosting tourism consumption of a natural protected area interpreted as ideal as post-Fordist real space and identify profiles of tourists in protected areas. Also if tourism products linked to nature, culture and cuisine can help to revitalize the Ligurian coastal tourism 5. Checking if the regional system of protected areas has produced results in both environmental protection and endogenous development through tourism. 6. Quantifying the actual supply of the areas studied. 7. Checking if the three parks studied were identified and developed specific objects of tourist consumption.