Towards the development of a new wavelet for ECG classification

In this paper an attempt has been made to determine the number of Premature Ventricular Contraction (PVC) cycles accurately from a given Electrocardiogram (ECG) using a wavelet constructed from multiple Gaussian functions. It is difficult to assess the ECGs of patients who are continuously monitored over a long period of time. Hence the proposed method of classification will be helpful to doctors to determine the severity of PVC in a patient. Principal Component Analysis (PCA) and a simple classifier have been used in addition to the specially developed wavelet transform. The proposed wavelet has been designed using multiple Gaussian functions which when summed up looks similar to that of a normal ECG. The number of Gaussians used depends on the number of peaks present in a normal ECG. The developed wavelet satisfied all the properties of a traditional continuous wavelet. The new wavelet was optimized using genetic algorithm (GA). ECG records from Massachusetts Institute of Technology-Beth Israel Hospital (MIT-BIH) database have been used for validation. Out of the 8694 ECG cycles used for evaluation, the classification algorithm responded with an accuracy of 97.77%. In order to compare the performance of the new wavelet, classification was also performed using the standard wavelets like morlet, meyer, bior3.9, db5, db3, sym3 and haar. The new wavelet outperforms the rest

Biochemical effects of cadmium, salinity and temperature on the catabolism of proteins and purines in oreochromis mossambicus (Peters)

In the present investigation, three important stressors: cadmium ion (Cd++), salinity and temperature were selected to study their effects on protein and purine catabolism of O. mossambicus. Cadmium (Cd) is a biologically nonessential metal that can be toxic to aquatic animals. Cadmium is a trace element which is a common constituent of industrial effluents. It is a non-nutrient metal and toxic to fish even at low concentrations. Cadmium ions accumulate in sensitive organs like gills, liver, and kidney of fish in an unregulated manner . Thus; the toxic effects of cadmium are related to changes in natural physiological and biochemical processes in organism. The mechanics of osmoregulation (i.e. total solute and water regulation) are reasonably well understood (Evans, 1984, 1993), and most researchers agree that salinities that differ from the internal osmotic concentration of the fish must impose energetic regulatory costs for active ion transport. There is limited information on protein and purine catabolism of euryhaline fish during salinity adaptation. Within a range of non-lethal temperatures, fishes are generally able to cope with gradual temperature changes that are common in natural systems. However, rapid increases or decreases in ambient temperature may result in sub lethal physiological and behavioral responses. The catabolic pathways of proteins and purines are important biochemical processes. The results obtained signifies that O. mossambicus when exposed to different levels of cadmium ion, salinity and temperature show great variation in the catabolism of proteins and purines. The organism is trying to attain homeostasis in the presence of stressors by increasing or decreasing the activity of certain enzymes. The present study revealed that the protein and purine catabolism in O. mossambicus is sensitive to environmental stressors.