Speech intelligibility in noise-induced hearing loss: effects of high-frequency compensation

This dissertation examines the frequency response that results in the maximum level of speech intelligibility for persons with noise-induced hearing loss.

Role of alpha synuclein in noise induced hearing loss

The recent discovery of the contribution of alpha synuclein in the auditory system prompted further investigation of its functional role. Auditory brainstem response (ABR) and gap detection testing were completed on wild-type and transgenic M83 mice to assess the role of alpha synuclein in noise-induced hearing loss and central auditory function.

Optimal dose of Kanamycin for protection from noise induced hearing loss

Young CBA/J mice were injected with kanamycin under varying schedules then exposed to noise in order to determine the boundary conditions for cochlear protection against noise.

Efficacy of a combined drug therapy for ameliorating noise-induced hearing loss

Experiments investigated the median effective dose of antiepileptic drugs and synthetic glucocorticoids for the prevention and treatment of noise-induced hearing loss for C57BL/6J mice. We also tested the possible synergistic effects of combining drugs from the two drug families.

Differential sensitivity to tonal frequency and to the rate of modulation of broad-band noise by hearing-impaired listeners

This dissertation examined whether a hearing impairment of the auditory end-organ has the same or a differential effect on the place and periodicity processes. Differential sensitivities for four normally hearing listeners and for both ears of five patients with unilateral Meniere’s disease were measured for tonal frequency and rate of sinusoidally amplitude-modulated noise at common frequencies and rates of the stimulus.

Noise levels and hearing conservation in a water treatment facility

This paper describes a study assessing the sound levels and noise exposures of a municipal water treatment plant to determine the level of employee noise exposure dosages and to make any necessary recommendations regarding reducing the risk of noise induced hearing loss in employees.

Hearing hazards to firefighters

This paper examines the risks of occupational noise induced hearing loss in firefighters. OSHA and National Institute for Occupational Safety and Health (NIOSH) guidelines are described and noise data collected from the Blue Island (Illinois) Fire Department is analyzed.

Noise exposure in the fire department

This paper discusses noise exposure to firefighters on the job and whether this contributes to noise induced hearing loss.

Comparison of long term cochlear noise injury and age-related cochlear degeneration in mice

This paper studies and compares age related hearing loss and noise-induced hearing loss in mice, and the different cell types that are affected by aging and noise.

The effects of noise exposure on nitric oxide synthase knockout mice

This paper studies the role of nitric oxide (NOS 1, NOS 2, and NOS 3 genes) in the mouse cochlea and in noise-induced hearing loss (NIHL). Mice genetically deficient of the NOS 2 and NOS 3 genes were protected from NIHL, indicating that one or both of these genes may be responsible for producing nitric oxide that damages the inner ear when exposed to harmful levels of noise.

Genetic and temporal aspects of protection by kanamycin against cochlear noise injury

Experiments explored the minimal kanamycin dosing regimen that renders protection against noise induced hearing loss in young CBA/J mice. We also tested the age-dependence of protection in CBA/J as well as the dependence of protection on a particular genetic background in experiments using young C57BL/6J and CBA/CaJ mice.

Genetic influences on hypoxic conditioning

This paper addresses the relationship between noise-induced hearing loss (NIHL) and hypoxic conditioning prior to noise exposure. The study begins the process of determining the number and characteristic of the gene(s) involved in the cochlear hypoxic conditioning response.

An educational curriculum outline for teaching sound and hearing in elementary schools

This paper provides curriculum on noise, ears, hearing and deafness for elementary school children.

Effect of unilateral hearing loss on the speech-evoked auditory brainstem response in the presence of noise

Speech-evoked auditory brainstem responses (ABRs) were acquired in quiet and in the presence of noise at two study sessions to investigate 1) test-retest variability and 2) subcortical representation of speech stimuli. Participants were adults with normal hearing in both ears who listened monaurally and adults with unilateral deafness. Results indicate consistency in responses across sessions and several differences between hearing groups for magnitudes of discrete components.

Temporal processing in listeners with unilateral hearing loss

Temporal processing is examined for sounds delivered to the intact ear of individuals with unilateral hearing, and delivered to one ear of individuals with normal, bilateral hearing. Two temporal processing skills are assessed: 1) the ability to detect sinusoidal amplitude modulation of a wide-band noise, for various modulation frequencies, and 2) the just-noticeable-difference for temporal complexity of random-spectrogram-sounds.