Hackstaff's new guide book of Niagara Falls : illustrated with a new map and views of the falls.

Title vignette.

Welland Canal Survey of Lands Nathan Pawling 1826; includes map and text.

Survey map and description of Nathan Pawling's land created by The Welland Canal Company. Included is a written description of the land along with a drawing of the land. Noteable features include; the dock, pier and tow path. The original bed of 12 mile creek is also noted on the map. Surveyor notes are seen in pencil on the map. The map notes the division of land between Pawling and Robert Brown's land. Click on 'detail' to see Map.

Notice that the Port Dalhousie and Thorold Railway map and plans have been certified by commissioners

Notice that the Port Dalhousie and Thorold Railway map and plans have been certified by commissioners. This is signed “secretary”, n.d.

The cloning and reconstitution of a bovine adenovirus type 2 E3 deletion mutant and the sequencing and analysis of the early 4 region

Recombinant Adenoviruses (Ads) have been shown to have potential applications in three areas: gene therapy, high level protein expression and recombinant vaccines.' At least three different locations within the Ad genome can be deleted and subsequently used for the insertion of foreign sequences. These include the Early 3 (E3), Early 1 (E1) and Early 4 (E4) regions. Viral vectors of this type have been well studied in Human Ads 2 and 5, however one has not yet been constructed for Bovine Adenovirus Type 2 (BAV2). The E3 region is located between 76.6 and 86 m.u. on the r-strand and is transcribed in a rightward direction. The gene products of the Early 3 region (E3) have been shown to be non-essential for viral replication, in vitro, but are required for host immunosurveillance. This study represents the cloning and reconstitution of a BAV2 E3 deletion mutant. A deletion of 1800bp was made within the E3 region of BAV2 and the thymidine kinase gene was subsequently inserted in the deleted area . . The plasmid pdlE3-4tk1 (23.4Kbp) was constructed and used to to facilitate homologous recombination with the wild type BAV2 to produce a mutant. Southern Blotting and Hybridization results suggest the presence of a BAV2 E3 deletion mutant with thymidine kinase sequences present. The E4 region of Human Adenovirus types 2 and 5 is located at the extreme right end of the genome (91.3 map units - 99.1 map units) and is transcribed in a leftward direction giving rise to a complicated set of differentially spliced mRNAs. Essentially there are 7 open reading frames (ORFs) encoding for at least 7 polypeptides. The gene products encoded by the E4 region have been shown to be essential for the expression of late viral genes, host cell shutoff and normal viral growth. We have cloned and sequenced the right end segment between 90.5 map units and 100 map units of the BAV2 genome. The results show several open reading frames which encode polypeptides exhibiting homology to three polypeptides encoded by the E4 region of human adenovirus type 2. These include the 14kDa protein encoded by ORF1, the 34kDa protein encoded by ORF6 and the 13kDa protein encoded by ORF3. The nucleotide sequence, restriction enzyme map, and ORF map of the E4 region could be very useful in future molecular manipulation of this region and could possibly explain the slow growth rate of BAV2 in MDBK cells.

Welland Canal Survey of Lands Estate of Hall Davis and Jeremiah Adley 1834

Survey map and description of the Estate of Hall Davis and Jeremiah Adley's land created by The Welland Canal Company. Included is a written description of the land along with a drawing of the land. Noteable features include; Holland road, Adley's house, waste weir. The total land for the Estate of Hall Davis is 27 acres and 2 perches. The total land for Adley is 3 acres. The deed for the Estate of Hall Davis is dated August 16th 1834 and contains Samuel Swayze's name. Swayze's name is also written under Hall Davis' name. The deed for Adley's land is dated December 1st 1827. Surveyor notes are seen in pencil on the map.

Welland Canal Survey of Lands Isabella Steward and William Sanderson, 1826

The first survey map and description is of Isabella Steward's land created by The Welland Canal Company. Included is a written description of the land along with a drawing of the land. Noteable features include; high water mark. The survey was signed and submitted on August 23rd, 1826. The land totals 1/4 of an acre. The second survey map and description is of William Sanderson's land created by The Welland Canal Company. Included is a written description of the land along with a drawing of the land. Noteable features include; line between Sanderson and Clendenning's land, line between Sanderson and Adam's land, canal. The survey was signed and submitted on August 23, 1826. The land totals 14 perches and 1 road. Surveyor notes are seen in pencil on the map. This image contains two seperate surveys.

Welland Canal Survey of Lands Michael and Jacob Silverthorn, 1834

Survey map and description of Michael and Jacob Silverthorn's land created by The Welland Canal Company. Included is a written description of the land along with a drawing of the land. Noteable features include; line between Burger and Silverthorn's land, reservoir, wood land, road leading to Quaker settlement, line between Jacob and Michael Silverthorn's land. The deeds for both lands are dated September 25, 1834. Surveyor notes are seen in pencil on the map.

Chautauqua Manoeuvre Map - 1915

A map of Lake Ontario near Niagara on the Lake. The map is titled Chautauqua Manoeuvre Map and is dated May 28, 1915.

Welland Canal Survey of Lands James Gordon

Survey map and description of James Gordon's land created by The Welland Canal Company. Included is a written description of the land along with a drawing of the land. The map contains a large pond and notes the seperation between lots 20 and 21. No scale is noted, but chains and inches are being used throughout the description of land. Surveyor notes are seen in pencil on the map. Click on 'detail' to see Map

Welland Canal Survey of Lands William May Jr., 1826

Survey map and description of William May Jr.'s land created by The Welland Canal Company. Included is a written description of the land along with a drawing of the land. The land is described as having 2 good acres and the rest being swamp. The property borders 12 mile creek in Grantham township. Noteable features include; a large pond, division line between lots 20 and 21 as well as 21 and 22, concession line. Surveyor notes are seen in pencil on the map. Click on 'detail' to see Map

Welland Canal Survey of Lands Peter May, 1826

Survey map and description of Peter May's land created by The Welland Canal Company. Included is a written description of the land along with a drawing of the land. Noteable features include; a large pond, the original bed of the 12 Mile Creek. Surveyor notes are seen in pencil on the map. The property is on the second concession in Grantham. Click on 'detail' to see Map

Welland Canal Survey of Lands Robert Brown, 1827

Survey map and description of Robert Brown's land created by The Welland Canal Company. Included is a two page written description of the land along with a drawing of the land. Noteable features include; line between Grantham and Louth townships, bed of the 12 mile creek. Surveyor notes are seen in pencil on the map, including notes about the deed to the land.

Welland Canal Survey of Lands Robert Brown 1827, land description #2

Survey map and description of Robert Brown's land created by The Welland Canal Company. Included is a two page written description of the land along with a drawing of the land. Noteable features include; line between Grantham and Louth townships, bed of the 12 mile creek. Surveyor notes are seen in pencil on the map, including notes about the deed to the land.

Welland Canal Survey of Lands John Martindale

Survey map and description of John Martindale's land created by The Welland Canal Company. Included is a written description of the land along with a drawing of the land. Noteable features include; property line between Martindale and Tenbroeck properties, original bed of 12 mile creek, tpw path diagram for the Welland canal on the wrong side of the diagram should be on the east side. The land was originally in the posession of William Ball when the original land survey was completed by G. Keefer in 1831. The land was also surveyed by Wm. Rykert. The description and sketch was not used in making the deed for the land. Surveyor notes are seen in pencil on the map.

Welland Canal Survey of Lands Jacob Tenbroeck, 1828

Survey map and description of Jacob TenBrock's land created by The Welland Canal Company. Included is a written description of the land along with a drawing of the land. Noteable features include; tow path, 12 mile creek, property line between Peter May and Jacob Tenbroeck. The land includes part of lot no.22 in the 2nd and 3rd concession of Grantham. The land is a total of 26 acres and contains 1 road. Surveyor notes are seen in pencil on the map.