Broadside Reporting the Fenian Invasion of Canada, June 4 1866

The collection consists of 6 broadsides reporting the events of the Fenian invasion of Canada on June 2 and 3, 1866. Three of the broadsides are titled Leader Extra, two are titled Globe Extra, and the last is titled News Extra. This one is titled Leader Extra and leads with the heading "Fenian Prisoners Twenty-One of them in Toronto Jail. Also included, "Latest American Reports: Interesting News from the East".

Total synthesis of (S)-4-hydroxy-[a]-Lapachone

(S)-4-Hydroxy-a-lapachone has been prepared for the first time. The commercially available compound 2-acetyl-1-naphthol was used as the starting material. The synthesis involved methylation, followed by Baeyer-Villiger oxidation, and hydrolysis of the acetate to give 1-methoxy-2-naphthol. After protecting of the hydroxyl group, t-BuLi was used to form 3-(3',3'-dimethyl-acryloyl)-1- meth oxy-2- (meth oxymethoxy)-naphthalen e. eycl izationand oxidation then gave 4-keto-a-lapachone. Finally enzymic biotransformation by Mortierella isabellina ATCC 42613 was used to yield the target compound. The enantiomeric excess of the product was determined to be ~98% by using 1H NMR chiral shift analysis. The overall yield is 80/0. The biological activity of (S)-4-hydroxy-alapachone and its acetate are under investigation.

An oration, delivered at Milford, N.H., March 9, 1815, occasioned by the Treaty of Peace, made and notified between Great Britain and the United States

Printed by R. Boylston

Exploring the Current State of Grades 4 to 8 Science Education in Ontario

This study sought to explore the current state of Grades 4 to 8 science education in Ontario from the perspective of Junior/Intermediate (J/I) teachers. The study’s methodology was a sequential 2-phased mixed methods explanatory design denoted as QUAN (qual)  qual. Data were collected from an online survey and follow-up interviews. J/I teachers (N = 219) from 48 school boards in Ontario completed a survey that collected both quantitative and qualitative data. Interviewees were selected from the survey participant population (n = 6) to represent a range of teaching strategies, attitudes toward teaching science, and years of experience. Survey and interview questions inquired about teacher attitudes toward teaching science, academic and professional experiences, teaching strategies, support resources, and instructional time allotments. Quantitative data analyses involved the descriptive statistics and chi-square tests. Qualitative data was coded inductively and deductively. Academic background in science was found to significantly influence teachers’ reported level of capability to teach science. The undergraduate degrees held by J/I science teachers were found to significantly influence their reported levels of capability to teach science. Participants identified a lack of time allocated for science instruction and inadequate equipment and facilities as major limitations on science instruction. Science in schools was reported to be of a “second-tiered” value to language and mathematics. Implications of this study include improving undergraduate and preservice experiences of elementary teachers by supporting their science content knowledge and pedagogical content knowledge.

Port Dalhousie and the Thorold Railway pay roll for the months of June, July, August and September, 1854

Port Dalhousie and the Thorold Railway pay roll for services of engineering and contingencies furnished for the months of June, July, August and September, 1854.

Port Dalhousie and the Thorold Railway pay roll for the months of June, July, August and September, 1854, signed by S.D. Woodruff, Sept. 30, 1854

Port Dalhousie and the Thorold Railway pay roll for services of engineering and contingencies furnished for the months of June, July, August and September, 1854, signed by S.D. Woodruff, Sept. 30, 1854.

Port Dalhousie and the Thorold Railway pay roll for the months of June, July and August, 1855, signed by S.D. Woodruff. There is an envelope included with this document, Aug. 21, 1855

Port Dalhousie and the Thorold Railway pay roll for services of engineering and contingencies furnished for the months of June, July and August, 1855, signed by S.D. Woodruff. There is an envelope included with this document, Aug. 21, 1855.

Port Dalhousie and the Thorold Railway pay roll for the months of June, July and August, 1856, signed by S.D. Woodruff, Sept. 2, 1856

Port Dalhousie and the Thorold Railway pay roll for services of engineering and contingencies furnished for the months of June, July and August, 1856, signed by S.D. Woodruff, Sept. 2, 1856.

Chart of estimate #8 of work done by John Williams during the month of June

Chart of estimate #8 of work done by John Williams during the month of June. This is signed by Fred Holmes, June 1856

Estimate of work done by A. Cook on the marsh lands main drain during the month of June 1857

Estimate of work done by A. Cook on the marsh lands main drain during the month of June 1857. This is signed by Fred Holmes, June 30, 1857.

Important state papers : declaration of war, Washington, June 18, 4 o'clock, P.M.

Message to the Senate and House of Representatives of the United States / James Madison -- Report : the Committee on Foreign relations, to whom was referred the message of the President of the United States of the 1st of June, 1812 -- An Act, declaring war between the United Kingdom of Great Britain and Ireland and the dependencies thereof, and the United States of America and their territories -- Address of the Senate to the people of the Commonwealth of Massachusetts.