Frederick Sager letter, 1847

The letter was intended to communicate to Dexter D’Everado, Supt. Of Niagara District Schools, that School Section No. 6 in the Township of Bertie had elected school trustees on 12 January 1847. The trustees were Thomas Shedding, Luke Lee and Frederick Sager, Chairman.

Electrogenic proton/L-glutamate symport in isolated asparagus sprengeri mesophyll cell

Medium' alkaliniiation occurred -lipon the addition of L-Glu to mechanically isolated Asparagus sprenger-i mesophyll cells suspended in 1 mM CaS04. Alkalinization resulted from the coupled entry of H+ and L-Glu anion into the cells. This H+ IL-Glu symport did not stimulate K+ efflux. K+ efflux has been observed during H~ lamino acid symport in other systems. The stimulation of K+ efflux by proton coupled symport is regarded as an indicator of a plasma membrane depolarizing electrogenic symport process. H+ IL-Glu symport in Asparagus sprengerimesophyl1 cells was investigated to determine whether or not the process was electrogenic. The rate of uptake of 0.25 11M 3H-MTPP+ ( Methyltriphenylphosphonium, methyl-3H ) is a probe for monitoring changes in the membrane potential. 3HMTPP+ uptake was reduced by K+ or CCCP, agents known to depolarize the membrane potential. Uptake of 3H-MTPP+ was also inhibited by L-Glu but not by D-Glu. Conversely, 10 mM external MTPP+ inhibited the uptake of 14C-U-LGlu. Simultaneous measurements of the rates of 14C-U-L-Glu uptake and L-Glu dependent H+ influx showed that the molar stoichiometry of H+ IL-Glu symport was 2 to 1. K+ or Na+ stimulated H+ efflux was completely inhibited by DCCD, DES, oligomycin and antimycin reagents which inhibit ATP driven H+ efflux. The H+ efflux \Vas also stimulate.d by the weak acids, butyric acid and acetic acid, which are known fo-aCidify the cytoplasm. This weak acid stimulated H+ efflux was also completely inhibited by oligomycin. It was calculated that net L-Glu dependent H+ influx increased by 100% in the presence of oligomycin and that despite net medium alkalinization H+ IL-Glu symport stimulates ATP dependent H+ efflux. 11 The data presented in this study indicate that H+ IL-Glu symport is electrogenic. The data also show that ATP dependent Ht efflux rather than K+ efflux is the- process compensating for thi~ electrogenic H+ IL-Glu symport.

A national monument to Laura Secord : why it should be erected, an appeal to the people of Canada /

Bibliography: p. 16.

A national monument to Laura Secord : why it should be erected, an appeal to the people of Canada

Bibliography: p. 16. Printed by Imrie, Graham and Co.

Welland County Records, 1961-1989

The origins of the Welland County Fair date back to the founding of the County of Welland in 1852. A provincial charter was issued in 1853 to create the Welland County Agricultural Society that was to operate the Fair. In 1970, the Welland County Fair became the Niagara Regional Exhibition, and the Society became known as the Niagara Regional Agriculture Society. The Society seeks to “encourage interest, promote improvements in and advance the standards of agriculture, domestic industry and rural life”. The Welland Festival of Arts was developed in 1986 in order to revitalize the town’s economy. An “outdoor art gallery” was created by painting murals on buildings that depicted the town’s heritage, a concept successfully adopted by the town of Chemainus, B.C. The first mural was completed in the summer of 1988, and by 1991 there were a total of 28 murals around the city. The endeavour proved successful: in the years that followed the creation of the Festival, two new hotels were constructed, a third was expanded, and there was an addition to the Seaway Mall to accommodate the increased tourist traffic. Optimist International is a non-profit organization that strives to “bring out the best in kids” . The first Canadian club was formed in Toronto in 1924. The Welland branch of the Optimist Club was founded in 1937. The first Welland County General Hospital opened in 1908. As the population increased, it became necessary to expand the existing facilities. Additions were made to the original structure with an East wing in 1930 and a children’s ward in 1931. However, in the 1950’s, the hospital was operating beyond optimum capacity and the need for a larger facility was clear. It was decided that a new hospital would be built, which opened in April 1960. The new hospital had 259 beds and 51 bassinets. Further additions were made in 1967 and 1978. The County of Welland was formed in 1850 when it was officially separated from Lincoln County, however, the two counties continued to operate together until 1856 when a new County building and jail for Welland County were completed. That same year, the first meeting of the Council of the Corporation of Welland County took place. The final meeting of the Council took place on December 18, 1969. The following year, the County of Welland merged with Lincoln County to form the Regional Municipality of Niagara. The Welland Mills in Thorold, Ont., was built in 1846-1847 by Jacob Keefer and is thought to have been one of the largest flour mills in Upper Canada. Ownership of the mill changed several times over the years and previous owners include the Howland family, the Hedley Shaw Milling Company and the Maple Leaf Milling Company. In 1986, the building received a heritage plaque from the Ontario Heritage Foundation, an agency of the Ontario Ministry of Culture and Recreation. At this time, the mill was no longer in operation and was being used for storage by Fraser, Inc. By 2006, the dilapidated building had been redeveloped into18 apartments and 2 floors of commercial space, while maintaining many heritage features. The building is currently known as the Welland Mills Centre.

H.A.S. Dearborn letter, May 29, 1812

H.A.S. (Henry Alexander Scammell) Dearborn (1783-1851) was the son of Henry Dearborn, the American politician and veteran of the Revolutionary War and War of 1812. In the War of 1812, H.A.S Dearborn served as Brigadier General of the volunteer forces, responsible for the defence of Boston Harbour. From 1812-1829 he was collector of customs in Boston, from 1831-1833 he served as a representative from Massachusetts in the United States Congress, was adjutant general of Massachusetts from 1834-1843 and mayor of Roxbury from 1847-1851. Letter transcription: Dear Sir, My success in the line of recruiting has exceeded my most sanguine expectations. I have enlisted 24 1st Lt. 30—my 2nd Lt. 13, and my Ensign 9—Total 76. All very [ablebodied] men. In all probability my company will be full before the last day of June. I shall be in Boston on the 10th of June. I have not yet had the pleasure to hear of the arrival of your father at Boston. Please to offer my respects to your family, and to all my friends in the [office]. In haste, Yours, A.M. Clary.

Wakeman Burritt fonds, 1807-1814

Wakeman Burritt (1785-1847) was a merchant and ship owner who conducted his business in New York, New Orleans, LA, Charleston, SC, and the West Indies. Despite the difficulties that the Embargo Act of 1807 and the War of 1812 posed to trade and commerce, Burritt managed to run a successful business, dealing in commodities such as foodstuffs, cloth, cotton, and soap. He owned three ships, the Brig Cannon, Brig Eunice and Brig Sampson. In 1809, he married Grace Burr (1787-1874). Together they had at least one child, Francis Burritt (1811-1861).

Indenture between Duncan and Margaret McFarland and Duncan Campbell

Indenture (vellum) of bargain and sale between Duncan and Margaret McFarland of Port Robinson to Duncan Campbell of Port Robinson for part of Lot no. 202 in the township of Thorold - instrument no. 673, November 30, 1847.

List tracing Details of Water Race to go through the Lands of Phelps, Clendinnan, Sanderson, Butler, and Chase

List (4 pages of printed material) tracing the details of the water race to go through the lands of Phelps, Clendinnan, Sanderson, Butler and Chase. This includes a copy of the following: the authority dated Dec. 22, 1829; a letter of encouragement dated Oct. 24, 1833; a transfer from Dittrick, Adams and others to the Welland Canal Company dated Dec. 6, 1834; a lease from the Welland Canal Co. to Adams and others dated Nov. 28, 1834 and the terms of the indenture dated May 24, 1847.

Receipt to Samuel Woodruff from E. Williams

Receipt to Samuel Woodruff from E. Williams, Aug. 18, 1847.

Receipt to Samuel D. Woodruff from Mr. Ashford

Receipt to Samuel D. Woodruff from Mr. Ashford for board, Dec. 31, 1847.

Letter - D.K. Minor to S.D. Woodruff

Letter with the letterhead Franklin House, Chestnut Street, Philadelphia. The letter is addressed to S.D. Woodruff. The sender, D.K. Minor is sending nos. 25 and 37 of the volume for 184b of the R.R.J. [Railroad Journal]. He says that he is pleased to see that there is a prospect of an early movement in relation to the Great Western Railroad in Canada. [D. Kimball Minor was the founder of the American Railroad Journal], Jan. 18, 1847.

The letter is addressed to Samuel D. Woodruff and is signed by Thomas Steers

Letter which is very stained, fragile and has holes in it. Text is partially illegible and faded. The letter is addressed to Samuel D. Woodruff and is signed by Thomas Steers. It is written in ink, but someone has added comments in pencil. It regards Richard and William Woodruff. There are questions on the document which include: “Has M. Clement died interstate?” [in pencil – “he has”]; “Has he an heir at law other than” [the rest is faded, someone has written in pencil “he has, Richard and William Woodruff”], March 23, 1847.

Letter to S.D. Woodruff from Thomas Steers and W. M. Kelly

Letter to S.D. Woodruff from Thomas Steers and W. M. Kelly regarding the patent for Mrs. Clement. The writer says that he will write to Mr. Woodruff fully respecting the claim of the younger Clement, May 14, 1847.

Letter to Samuel D. Woodruff from Thomas Steers and W.M. Kelly

Letter to Samuel D. Woodruff from Thomas Steers and W.M. Kelly stating that they have been successful in getting the patent through for Mrs. Clement for Lot no.30, Concession 2 in Enniskillen. James Clement is not of age and he cannot transfer his right to his brother Joseph. There is no obstacle of the patent being issued in Richard’s name. There are some notes in pencil on this document. The document is torn, and stained, but text is not affected. The postmark on the outside is Montreal, June 26, 1847, June 25, 1847.