Post Card Album - Welland Canal

A collection of post cards (52 black & white and 47 colour) and photographs (26 black & white) of the Welland Canal. The photographs and post cards cover a range of years and locations, inlcuding St. Catharines, Port Colborne, Port Dalhousie; Humberstone, Thorold, Allanburg and Niagara Falls.

Welland Industry - Postcards

Board of five postcards of Welland. First postcard, Welland Riverside Mills. Second postcard, Plymouth Cordage Co., Welland, Ont. Third postcard, Ship Yard, Welland Canal, Welland, Ont. Fourth postcard, Welland Cordage Co., Fifth postcard, Cordage St.., Welland, Ont.

Upper Lakes Shipping Ltd. Vessels Scrapbook, 1964-1967, no date

The origins of Upper Lakes Shipping can be traced back to 1931, when Gordon Leitch, the general manager of Toronto elevators, sent Captain Bruce Angus to scout for potential ships that could be used to transport grain. The ship Sarnian was purchased as a result. It soon became apparent that more ships would be needed by the business, and Leitch subsequently partnered with James Norris of the Norris Grain Company, in order to transport their products more economically. The Upper Lakes and St. Lawrence Transportation Company (which later become known as Upper Lakes Shipping), was incorporated in 1932. In 1956, the company bought Port Weller Dry docks. At this point, the company began constructing new vessels designed to meet specific freight and classification needs.

Schooner Ranger document, 1810-1815

Partial transcription: Buffalo, August 15, 1815 This day settled all accounts between… respecting the purchase and sailing of the Schooner Ranger until she was laid up in the fare of 1811. For the value of the…of the said Schooner destroyed by the enemy in January 1813 and the rigging & c taken by the U.S. Navy Officers for the use of the Government a [Joint][appreciation] is to be made... Government for our mutual benefit. Porter & Barton for [the firm] of Porter Barton & Co. George Kibbe

Disease-Gene Association Using a Genetic Algorithm

Understanding the relationship between genetic diseases and the genes associated with them is an important problem regarding human health. The vast amount of data created from a large number of high-throughput experiments performed in the last few years has resulted in an unprecedented growth in computational methods to tackle the disease gene association problem. Nowadays, it is clear that a genetic disease is not a consequence of a defect in a single gene. Instead, the disease phenotype is a reflection of various genetic components interacting in a complex network. In fact, genetic diseases, like any other phenotype, occur as a result of various genes working in sync with each other in a single or several biological module(s). Using a genetic algorithm, our method tries to evolve communities containing the set of potential disease genes likely to be involved in a given genetic disease. Having a set of known disease genes, we first obtain a protein-protein interaction (PPI) network containing all the known disease genes. All the other genes inside the procured PPI network are then considered as candidate disease genes as they lie in the vicinity of the known disease genes in the network. Our method attempts to find communities of potential disease genes strongly working with one another and with the set of known disease genes. As a proof of concept, we tested our approach on 16 breast cancer genes and 15 Parkinson's Disease genes. We obtained comparable or better results than CIPHER, ENDEAVOUR and GPEC, three of the most reliable and frequently used disease-gene ranking frameworks.

Letter - E.C. Schmon to Arthur A. Schmon, 11 & 12 September 1918

Eleanore Celeste describes Arthur's departure for service one year ago. She also discusses a friend, Dick Hart, who was thought to have been a casualty of a torpedoed ship, but is now thought to be safe. She mentions that she will visit Mother Schmon and had played tennis with Gus. The letter is labelled number 159.

Letter - E.C. Schmon to Arthur A. Schmon, 20 December 1919

Eleanore Celeste discusses the ice breaker ship that travels to Quebec. Arthur has asked if the boat will travel the first trip soon and she responds that she is not sure if it will make the trip, but will wait until the New Year to find out more. She mentions that Arthur is going to buy her a fur for her Christmas gift. The letters are labelled number 78 & 79.

Persia steamboat poster, no date

The “Persia” was built in St. Catharines in 1873. From 1877 to 1894 the ship was owned by James Norris of St. Catharines. The Toronto and Montreal Steamboat Co. acquired the ship in 1894, followed by the Quebec Navigation Co. in 1907. A fire severely damaged the ship in 1911, and the following year the “Persia” was rebuilt as a barge.

Photograph - House Interior, Dining Room

Black and white photographs, 19 cm x 24 cm of the interior of an unidentified house showing a dining room with a model ship on the table. The photograph was taken by Wurts Brothers General Photographers of New York City (2 copies).

Disease-Gene Association Using Genetic Programming

As a result of mutation in genes, which is a simple change in our DNA, we will have undesirable phenotypes which are known as genetic diseases or disorders. These small changes, which happen frequently, can have extreme results. Understanding and identifying these changes and associating these mutated genes with genetic diseases can play an important role in our health, by making us able to find better diagnosis and therapeutic strategies for these genetic diseases. As a result of years of experiments, there is a vast amount of data regarding human genome and different genetic diseases that they still need to be processed properly to extract useful information. This work is an effort to analyze some useful datasets and to apply different techniques to associate genes with genetic diseases. Two genetic diseases were studied here: Parkinson’s disease and breast cancer. Using genetic programming, we analyzed the complex network around known disease genes of the aforementioned diseases, and based on that we generated a ranking for genes, based on their relevance to these diseases. In order to generate these rankings, centrality measures of all nodes in the complex network surrounding the known disease genes of the given genetic disease were calculated. Using genetic programming, all the nodes were assigned scores based on the similarity of their centrality measures to those of the known disease genes. Obtained results showed that this method is successful at finding these patterns in centrality measures and the highly ranked genes are worthy as good candidate disease genes for being studied. Using standard benchmark tests, we tested our approach against ENDEAVOUR and CIPHER - two well known disease gene ranking frameworks - and we obtained comparable results.

Letter - Howard Helliwell to S.D. Woodruff

Letter with letterhead “Sylvester Neelon, Vessel and Steamboat Owner, Merchant Miller and Manufacturer of Ship Timber” addressed to S.D. Woodruff regarding the pew at St. George’s Church. “This pew which was owned by Howard Helliwell is now at your disposal and the rent is paid up to Oct. 1st”, Oct. 2, 1886

I.O.D.E. Stamford Chapter Minutes, 1991-1994, n.d.

The Imperial Order Daughters of the Empire was founded by Margaret Polson Murray in 1900 following the outbreak of the second Boer War. The organization gave charitable aid to soldiers and it assisted the dependents of deceased soldiers. The federation of women was formed to promote patriotism, loyalty and service to others. The mayors of Canada's major cities were urged to call together the prominent women of their communities to join in this endeavour. In 1979, the name I.O.D.E. was officially adopted. The organization is federally chartered not-for-profit. The focus is on improving the quality of life for children, youth and the underprivileged through education, social services and citizenship programs. The membership list for this chapter has 1932 as the beginning date. On September 12, 1994, the group was disbanded. The Stamford Chapter was located in Niagara Falls, Ontario.

Niagara Falls Handbill Collection, 1838-1886, n.d. (non-inclusive)

According to legend, the Burning Springs were discovered by early natives in the Niagara Peninsula. Bridgewater Mills was built on the site of the spring. During the excavation of the factory; workmen uncovered the spring. Samuel Street and Thomas Clark recognized the potential of this as a tourist attraction so they built a wooden shelter over the spring. The spring was covered with a barrel with a pipe protruding from it. This became the first tourist attraction at Niagara. The Cave of the Winds was a cavern located behind the Bridal Veil Fall. It was originally named the Aeolus Cave. In 1920, a sudden rock fall from the ceiling killed 3 tourists. The cave was destroyed in 1955 as it was deemed dangerous. The captain of the Maid of the Mist was usually a farmer who owned the land where the ship docked. In 1846, the first steam powered Maid of the Mist was launched. By 1848, the first suspension bridge was built over the gorge and the main purpose of the Maid of the Mist was no longer to carry people who needed to travel, but now the focus was on people who wanted to view the Falls at close range. Source: http://www.niagarafrontier.com/burningsprings.html http://www.niagarafrontier.com/winds.html http://reservationsystems.com/niagara_daredevils/maid_of_the_mist.html

Commodore Hull Medallion, Poem and Presidential Messages

1 cardboard clam shell case with a bronze medallion in a front portal. The medallion is 6 cm. in circumference with a bust of Commodore Isaac Hull on the face. The medallion was designed by John Reich. A translation of the words inscribed on the front is: “Isaac Hull conquers in July 1812, the skilled by stratagem and in August, the strong in battle” On the back is a ship and the words “Horae Momento Victoria” which translate to “Victory in the space of an hour”. The title on the front of the box has the words “War of 1812, Jonathan Russell, Commodore Hull”. Only 126 of these medallions were estimated to be struck. Also within this collection is a poem written by Jonathan Russell and 2 messages from President James Madison.