Indenture between Henry and Mary Ellen Rogers and John Young

Indenture of bargain and sale between Henry and Mary Ellen Rogers of the Township of Niagara and John Young of the Township of Niagara regarding part of Lot no. 113 in the Township of Niagara - instrument no. 15071. Registered in the County of Lincoln on January 16, 1865 in Book C, folio 344, January 13, !865.

Indenture between Henry Hope Graham and Robert Hill to Joseph Walker

Indenture of deed of land situate between Henry Hope Graham and Robert Hill, both of London, England called England Esquire Executors and Trustees under the Last Will and Testament of Lieutenant General Percy Hill of London, England to Joseph Walker of Queenston, Ontario. This is in regard to parts of Lots no. 113, 114 and 115 in the Township of Niagara. This was registered on Nov. 10, 1885 – instrument no. 2075, Oct. 31, 1885.

Invitation to the Funeral of Infant Henry Howard Woodruff

Invitation to the funeral of infant Henry Howard Woodruff on March 17, 1868. He was the son of Henry and Emma Woodruff. This is accompanied by an envelope. March 16, 1868.

Letter - Henry O'Laughlin to H.K. Woodruff

Letter from Henry O’Laughlin, secretary of the Central Fire Station of St. Catharines, Ont. to H.K. Woodruff informing him that he was elected as an active member of the Citizens’ Hose Co. No. 1, March 14, 1883.

Indenture Abraham Fuller Atkinson, Henry Riggs Goodman and William Hamilton Merritt to Thomas Lees Helliwell

Indenture between Abraham Fuller Atkinson of St. Catharines, rector of St. George’s Church, Henry Riggs Goodman and William Hamilton Merritt, wardens of St. George’s Church, to Thomas Lees Helliwell for pew no. 15 in St. George’s Church, Mar. 21, 1857.

Postcard Addressed to Mr. Henry Woodruff

Postcard addressed to Mr. Henry Woodruff of St. Davids regarding 33 bags placed to Mr. Woodruff’s credit. The postcard is signed by John May, Aug. 6, 1883.

Crick, Henry A., includes Application for Loan, and Mortgage Loan Envelope

Crick, Henry A., includes Application for Loan, Jan. 8, 1885 and Mortgage Loan Envelope no. 637 for Jan. 1, 1885 – Jan. 1, 1890.

License no. 26 of season 1880/81 made out to S.D. Woodruff for 36 square miles in berth no. 192

License no. 26 of season 1880/81 made out to S.D. Woodruff for 36 square miles in berth no. 192, May 27, 1880.

Letter to S.D. Woodruff regarding a resolution passed that the engineer be requested to examine the fence built by the contractors alongside of the Henry Vandenburgh Farm

Letter to S.D. Woodruff regarding a resolution passed that the engineer be requested to examine the fence built by the contractors alongside of the Henry Vandenburgh Farm and report to the secretary as to whether this is a lawful fence, completed according to Williams’ contract. This is signed by Duncan McFarland, president. There is a reply written by S.D. Woodruff at the bottom of the letter stating that the fence is not built in accordance with the contract, Dec. 18, 1856.

Disbursements to Long Point Company, June 6, 1877 – May 31, 1880

Disbursements to Long Point Company (1 page, handwritten), June 6, 1877 – May 31, 1880.

Balances from June 6, 1877 - May 31, 1880

Balances (1 page, handwritten) from June 6, 1877 - May 31, 1880.

Balance sheet including copy of the cash book and auditor’s report for 12 months ending May 31, 1880

Balance sheet including copy of the cash book and auditor’s report (1 page, printed) for 12 months ending May 31, 1880.

Mirroring Enzymes: The Role of H-Bonding In HQuin-BAM Catalyzed Asymmetric Aza-Henry Reactions: A DFT Study into the Reactivity, Mechanism, and Origins of Selectivity

The exact mechanistic understanding of various organocatalytic systems in asymmetric reactions such as Henry and aza-Henry transformations is important for developing and designing new synthetic organocatalysts. The focus of this dissertation will be on the use of density functional theory (DFT) for studying the asymmetric aza-Henry reaction. The first part of the thesis is a detailed mechanistic investigation of a poorly understood chiral bis(amidine) (BAM) Brønsted acid catalyzed aza-Henry reaction between nitromethane and N-Boc phenylaldimine. The catalyst, in addition to acting as a Brønsted base, serves to simultaneously activate both the electrophile and the nucleophile through dual H-bonding during C-C bond formation and is thus essential for both reaction rate and selectivity. Analysis of the H-bonding interactions revealed that there was a strong preference for the formation of a homonuclear positive charge-assisted H-bond, which in turn governed the relative orientation of substrate binding. Attracted by this well-defined mechanistic investigation, the other important aspect of my PhD research addressed a detailed theoretical analysis accounting for the observed selectivity in diastereoselective versions of this reaction. A detailed inspection of the stereodetermining C-C bond forming transition states for monoalkylated nitronate addition to a range of electronically different aldimines, revealed that the origins of stereoselectivity were controlled by a delicate balance of different factors such as steric, orbital interactions, and the extent of distortion in the catalyst and substrates. The structural analysis of different substituted transition states established an interesting dependency on matching the shape and size of the catalyst (host molecule) and substrates (guest molecules) upon binding, both being key factors governing selectivity, in essence, offering an analogy to positive cooperative binding effect of catalytic enzymes and substrates in Nature. In addition, both intra-molecular (intra-host) and inter-molecular (host-guest, guest-guest) stabilizing interactions play a key role to the high π-facial selectivity. The application of dispersion-corrected functionals (i.e., ωB97X-D and B3LYP-D3) was essential for accurately modeling these stabilizing interactions, indicating the importance of dispersion effects in enantioselectivity. As a brief prelude to more extensive future studies, the influence of a triflate counterion on both reactivity and selectivity in this reaction was also addressed.

Time on marsh lands for the months of January, February, March and April for Fred Holmes, Joseph Simpson, Duncan Davidson, Rose Osborne, Henry Wilson and William Baird

Time on marsh lands for the months of January, February, March and April for Fred Holmes, Joseph Simpson, Duncan Davidson, Rose Osborne, Henry Wilson and William Baird. This is signed by Fred Holmes, April 28, 1857.

Engineering services in marsh lands drainage for the months of January, February, March and April for Fred Holmes, Joseph Simpson, D. Davidson, Rose Osborne, Henry Wilson and William Baird

Engineering services in marsh lands drainage for the months of January, February, March and April for Fred Holmes, Joseph Simpson, D. Davidson, Rose Osborne, Henry Wilson and William Baird. This is signed by S.D. Woodruff, May 1, 1857.