Letter - Donald Ziraldo to Moses Znaimer, with reply from Znaimer

A letter from Donald Ziraldo to Moses Znaimer regarding a holiday bottle of Icewine sent for the holidays. The bottle is mentioned in the letter because it is said to have been made during the last year's Annual Celebrity Icewine event. The names mentioned from the event are Steven Page of the music group Barenaked Ladies and Jim Cuddy of the group Blue Rodeo. The letter also includes a handwritten response from Znaimer thanking Ziraldo for the wine and mentions the Idea City Conference where Ziraldo will be speaking.

Letter to Mrs. Percy Band from Donald E. Loker

Letter (2 typed pages) to Mrs. Percy Band from Donald E. Loker, former American History master of the DeVeaux School, Niagara Falls, New York. Mr. Loker is enquiring about Maria and Sarah Woodruff. Samuel DeVeaux was married twice. He married Maria Woodruff, and after her death in 1815, he married her widowed sister, Sarah Woodruff, 1962.

Letter to S.D. Woodruff from Burrell, McEwen and Co.

Letter to S.D. Woodruff from Burrell, McEwen and Co. stating that the mantle mirror will not fit into the drawing room, Sept. 26, 1876.

Letter to S.D. Woodruff from Burrell, McEwen and Co.

Letter to S.D. Woodruff from Burrell, McEwen and Co. stating that they did not have the damask in sufficient quantity so they purchased all silk damask, Sept. 26, 1876.

Letter to Burrell, McEwen and Co. from [S.D. Woodruff]

Letter to Burrell, McEwen and Co. from [S.D. Woodruff] stating that he has enclosed another $8.00 to cover the balance of duties, Nov. 20, 1876.

Letter to Burrell, McEwen and Co. from [S.D. Woodruff]

Letter to Burrell, McEwen and Co. from [S.D. Woodruff] regarding the furniture and the looking glass which they have put in his home, Nov. 22, 1876.

Letter to Burrell, McEwen and Co. from [S.D. Woodruff]

Letter to Burrell, McEwen and Co. from [S.D. Woodruff] regarding payments made to them, Jan.5, 1877.

Receipt from Burrill, McEwen and Co. for Chinese clock

Receipt from Burrill, McEwen and Co. for Chinese clock, Oct. 12, 1876.

Receipt from Burrill, McEwen and Co. for payment on account

Receipt from Burrill, McEwen and Co. for payment on account, Nov. 13, 1876.

Receipt from Burrill, McEwen and Co. for payment on account

Receipt from Burrill, McEwen and Co. for payment on account, Dec. 28, 1876.

Receipt from Burrill, McEwen and Co. for payment on account

Receipt from Burrill, McEwen and Co. for payment on account, Nov. 23, 1876.

Indenture between Richard Leonard, sheriff of the District of Niagara (regarding lands seized from John Donald McKay) to Robert Dickson

Indenture between Richard Leonard, sheriff of the District of Niagara (regarding lands seized from John Donald McKay) to Robert Dickson. The land consists of ½ an acre located in Lot no. 96 in the Town of Niagara – instrument no. 8600. This was recorded on May 4th, 1832 in Book N, folio 276- 277 in the registry of Lincoln and Haldimand Counties, Oct. 13, 1824.

1970-71 Curling Team

1970-71 Brock curling team in action. From L to R: Rob Kelly, John Donald, and John Goodwin

1971-72 Varsity Curling

Pictured here from left to right are: Front - John Donald, Greg Reid, Steve Thomas, John Glennie, and Mike Wilder. Back - Ed Davis (Coach). The 1971-72 curling team boasted a number of achievements including being the Niagara Distrcit Major Champions, University of Toronto Bonspiel Champions, and the Ontario University Athletic Association Champions.

Amputation and heat induced protein synthesis in the regenerating forelimb of Notophthalmus viridescens

This thesis compares the responses of regenerating forelimb tissues of the newt Notophthalmu..f vlridescens to the stresses of hyperthermia and ID.echanical injury of amputation. In particular, both quantitative and qualitative changes in the synthesis of soluble proteins in stump tissues, including those of the heat shock protein family (HSP70-1ike) were examined. Results from SDS-PAGEfluorography indicate that the trauma of amputation mimics the heat shock response both quantitatively and temporally in its transient repression of the synthesis of most normal cellular proteins, and qualitatively. in the locaJized expression of two unique proteins (hsp30 and hsp70). Fluorography of proteins separated by twodimensional gets revealed that thelCl4:alizedt amputation induced 70kDa protein (amp70) was distinct from the more basic newt hsp/hsc70 isoforms. Although limb amputation resulted in an increase in the synthesis of HSP70 mRNA analogous to that induced by heat 3.b.OCKf amp70 did not cross-react with murine monoclonal antibodies directed against both the inducible and cognate HSP70 proteins of the human. Thus, the possible relationship of amp70 to other members of the HSP70-1ike protein family remains unclear. Western analyses indicated that the levels of the constitutive form of HSP70 (hsc70) were found to be regulated in a stage-dependent manner in the distal stump tissues of the regen,erating forelimb of the newt. The highest levels were found in the mid-late bud stage, a period during which rapidly dividing blastema cells begin to redifferentiate in a proximodistal direction. Immediately after amputation) hsc70 synthesis and accumulation was depressed below steady-state levels measured in the unamputated limb~ The results are discussed in light of a possible role for HSPs and amputatio~ induced proteins in the epimorphic regeneration of the amphibian limb.