3D Stripixel Detectors Simulation

Solid-state silicon detectors have replaced conventional ones in almost all recent high-energy physics experiments. Pixel silicon sensors don't have any alternative in the area near the interaction point because of their high resolution and fast operation speed. However, present detectors hardly withstand high radiation doses. Forthcoming upgrade of the LHC in 2014 requires development of a new generation of pixel detectors which will be able to operate under ten times increased luminosity. A planar fabrication technique has some physical limitations; an improvement of the radiation hardness will reduce sensitivity of a detector. In that case a 3D pixel detector seems to be the most promising device which can overcome these difficulties. The objective of this work was to model a structure of the 3D stripixel detector and to simulate electrical characteristics of the device. Silvaco Atlas software has been used for these purposes. The structures of single and double sided dual column detectors with active edges were described using special command language. Simulations of these detectors have shown that electric field inside an active area has more uniform distribution in comparison to the planar structure. A smaller interelectrode space leads to a stronger field and also decreases the collection time. This makes the new type of detectors more radiation resistant. Other discovered advantages are the lower full depletion voltage and increased charge collection efficiency. So the 3D stripixel detectors have demonstrated improved characteristics and will be a suitable replacement for the planar ones.

WWW-pohjaisen julkaisurekisteriohjelmiston suunnittelu ja toteutus

Työn tavoitteena oli suunnitella ja toteuttaa uudistettu versio Lappeenrannan teknillisen yliopiston kirjaston käyttämästä WWW-pohjaisesta julkaisurekisteriohjelmasta. Työssä käsitellään muuttuneita tarpeita ja syitä, jotka johtivat uuden ohjelmiston toteuttamiseen. Ohjelmiston uuteen versioon toteutettiin uusi ohjelmistoarkkitehtuuri, joka perustuu eri toiminnot toteuttaviin komponentteihin rajapintoineen. Tässä raportissa kuvataan ohjelmistoon liittyvät vaatimukset, projektin toteutukseen käytetyt tekniset ratkaisut sekä ohjelmiston toiminnallisuus käyttöliittymäkuvineen. Lisäksi käsitellään Ajax-tekniikoiden hyödyntämistä ohjelmiston käyttöliittymän vuorovaikutteisuuden parantamiseen. Lopuksi käsitellään toteutunutta projektia ja lopputuloksen merkitystä.

Exploring Adaptive Implementation of On-Chip Networks

As technology geometries have shrunk to the deep submicron regime, the communication delay and power consumption of global interconnections in high performance Multi- Processor Systems-on-Chip (MPSoCs) are becoming a major bottleneck. The Network-on- Chip (NoC) architecture paradigm, based on a modular packet-switched mechanism, can address many of the on-chip communication issues such as performance limitations of long interconnects and integration of large number of Processing Elements (PEs) on a chip. The choice of routing protocol and NoC structure can have a significant impact on performance and power consumption in on-chip networks. In addition, building a high performance, area and energy efficient on-chip network for multicore architectures requires a novel on-chip router allowing a larger network to be integrated on a single die with reduced power consumption. On top of that, network interfaces are employed to decouple computation resources from communication resources, to provide the synchronization between them, and to achieve backward compatibility with existing IP cores. Three adaptive routing algorithms are presented as a part of this thesis. The first presented routing protocol is a congestion-aware adaptive routing algorithm for 2D mesh NoCs which does not support multicast (one-to-many) traffic while the other two protocols are adaptive routing models supporting both unicast (one-to-one) and multicast traffic. A streamlined on-chip router architecture is also presented for avoiding congested areas in 2D mesh NoCs via employing efficient input and output selection. The output selection utilizes an adaptive routing algorithm based on the congestion condition of neighboring routers while the input selection allows packets to be serviced from each input port according to its congestion level. Moreover, in order to increase memory parallelism and bring compatibility with existing IP cores in network-based multiprocessor architectures, adaptive network interface architectures are presented to use multiple SDRAMs which can be accessed simultaneously. In addition, a smart memory controller is integrated in the adaptive network interface to improve the memory utilization and reduce both memory and network latencies. Three Dimensional Integrated Circuits (3D ICs) have been emerging as a viable candidate to achieve better performance and package density as compared to traditional 2D ICs. In addition, combining the benefits of 3D IC and NoC schemes provides a significant performance gain for 3D architectures. In recent years, inter-layer communication across multiple stacked layers (vertical channel) has attracted a lot of interest. In this thesis, a novel adaptive pipeline bus structure is proposed for inter-layer communication to improve the performance by reducing the delay and complexity of traditional bus arbitration. In addition, two mesh-based topologies for 3D architectures are also introduced to mitigate the inter-layer footprint and power dissipation on each layer with a small performance penalty.

Integrating user experience into early phases of software development

The value and benefits of user experience (UX) are widely recognized in the modern world and UX is seen as an integral part of many fields. This dissertation integrates UX and understanding end users with the early phases of software development. The concept of UX is still unclear, as witnessed by more than twenty-five definitions and ongoing argument about its different aspects and attributes. This missing consensus forms a problem in creating a link between UX and software development: How to take the UX of end users into account when it is unclear for software developers what UX stands for the end users. Furthermore, currently known methods to estimate, evaluate and analyse UX during software development are biased in favor of the phases where something concrete and tangible already exists. It would be beneficial to further elaborate on UX in the beginning phases of software development. Theoretical knowledge from the fields of UX and software development is presented and linked with surveyed and analysed UX attribute information from end users and UX professionals. Composing the surveys around the identified 21 UX attributes is described and the results are analysed in conjunction with end user demographics. Finally the utilization of the gained results is explained with a proof of concept utility, the Wizard of UX, which demonstrates how UX can be integrated into early phases of software development. The process of designing, prototyping and testing this utility is an integral part of this dissertation. The analyses show statistically significant dependencies between appreciation towards UX attributes and surveyed end user demographics. In addition, tests conducted by software developers and industrial UX designer both indicate the benefits and necessity of the prototyped Wizard of UX utility. According to the conducted tests, this utility meets the requirements set for it: It provides a way for software developers to raise their know-how of UX and a possibility to consider the UX of end users with statistical user profiles during the early phases of software development. This dissertation produces new and relevant information for the UX and software development communities by demonstrating that it is possible to integrate UX as a part of the early phases of software development.

The Possibilities and Dosimetric Limitations of MLC-Based Intensity-Modulated Radiotherapy Delivery and Optimization Techniques

The use of intensity-modulated radiotherapy (IMRT) has increased extensively in the modern radiotherapy (RT) treatments over the past two decades. Radiation dose distributions can be delivered with higher conformality with IMRT when compared to the conventional 3D-conformal radiotherapy (3D-CRT). Higher conformality and target coverage increases the probability of tumour control and decreases the normal tissue complications. The primary goal of this work is to improve and evaluate the accuracy, efficiency and delivery techniques of RT treatments by using IMRT. This study evaluated the dosimetric limitations and possibilities of IMRT in small (treatments of head-and-neck, prostate and lung cancer) and large volumes (primitive neuroectodermal tumours). The dose coverage of target volumes and the sparing of critical organs were increased with IMRT when compared to 3D-CRT. The developed split field IMRT technique was found to be safe and accurate method in craniospinal irradiations. By using IMRT in simultaneous integrated boosting of biologically defined target volumes of localized prostate cancer high doses were achievable with only small increase in the treatment complexity. Biological plan optimization increased the probability of uncomplicated control on average by 28% when compared to standard IMRT delivery. Unfortunately IMRT carries also some drawbacks. In IMRT the beam modulation is realized by splitting a large radiation field to small apertures. The smaller the beam apertures are the larger the rebuild-up and rebuild-down effects are at the tissue interfaces. The limitations to use IMRT with small apertures in the treatments of small lung tumours were investigated with dosimetric film measurements. The results confirmed that the peripheral doses of the small lung tumours were decreased as the effective field size was decreased. The studied calculation algorithms were not able to model the dose deficiency of the tumours accurately. The use of small sliding window apertures of 2 mm and 4 mm decreased the tumour peripheral dose by 6% when compared to 3D-CRT treatment plan. A direct aperture based optimization (DABO) technique was examined as a solution to decrease the treatment complexity. The DABO IMRT technique was able to achieve treatment plans equivalent with the conventional IMRT fluence based optimization techniques in the concave head-and-neck target volumes. With DABO the effective field sizes were increased and the number of MUs was reduced with a factor of two. The optimality of a treatment plan and the therapeutic ratio can be further enhanced by using dose painting based on regional radiosensitivities imaged with functional imaging methods.

Helsingin seudun liikenteenhallinnan kärkihankkeiden päivitys 2011

Työn tavoitteena oli kokonaisnäkemyksen luominen Helsingin seudun liikenteenhallinnan tilasta ja kehitysnäkymistä sekä seuraavien tärkeimpien kehittämispolkujen tunnistaminen ja konkretisointi toimenpiteiksi. Työssä keskityttiin seuraaviin painopistealueisiin 1. Liityntäpysäköinnin informaation ja maksujärjestelmien kehittäminen 2. Liikenteenhallintakeskuksen toiminnan kehittäminen ja laajentaminen 3. Liikennejärjestelmän reaaliaikainen tilannekuva ja lyhyen aikavälin ennusteet 4. Pääkaupunkiseudun pääväylien ruuhkien ja häiriöiden hallinta 5. Joukkoliikenteen ajantasaisen matkustajainformaation kehittäminen. Työssä laadittiin katsaus kullakin painopistealueella jo tapahtuneeseen sekä käynnissä olevaan kehitystyöhön, kuvattiin esiin nousseita ongelmia ja laadittiin esitys vuoteen 2020 ulottuvasta toiminnallisesta tavoitetilasta sekä konkreettisista kehittämistoimista. Työssä järjestettiin myös tulevaisuustyöpaja, johon pyydettiin alustuksia valikoiduilta viranomaistahoilta, tutkijoilta ja palveluntuottajilta. Näiden keskustelujen kautta kirkastettiin seudun toimijoiden näkemystä älyliikenteen toimialan kehitysnäkymistä ja –tarpeista. Työn lopputuloksena syntyneeseen toimenpideohjelmaan kirjattiin yhteensä 30 hanketta. Näistä viisi hanketta valittiin työpajatyöskentelyn kautta varsinaisiksi kärkihankkeiksi, joiden toteutus on kriittistä liikkujien ja viranomaistyön palvelutason kannalta ja joka edellyttää usean toimijan yhteistyötä. Lisäksi tunnistettiin joukko seurattavia hankkeita. Valitut kärkihankkeet, käynnistämisen vastuutaho sekä tavoitteellinen käynnistysvuosi ovat seuraavat: 1. Liityntäpysäköinnin dynaamisen informaatiojärjestelmän pilotointi Hämeenlinnanväylän käytävässä Kehäradan asemilla (HSL 2012) 2. HSL:n alueen joukkoliikenteen häiriönhallinnan uudelleenorganisointi (HSL, Liikennevirasto 2012) 3. Seudullisen liikenteenhallintasuunnitelman laadinta verkollisen operoinnin kehittämiseksi häiriötilanteissa (ELY-keskus, Liikennevirasto 2013) 4. Reaaliaikaisen sujuvuustiedon tuottaminen ruuhkautuvalta pääkatu- ja alempiasteiselta maantieverkolta (Liikennevirasto, kunnat 2012) 5. Liikenteen vaihtuvan ohjauksen ja tiedottamisen hyödyntäminen pääväylien ruuhkautumisen ja häiriöiden hallinnassa. (ELY-keskus 2012) Kärkihankkeisiin ei liity sellaisia riippuvuuksia, että niitä ei voitaisi käynnistää ennen päätöksentekoa jostakin muusta investoinnista. Merkittävimmät riippuvuudet liittyvät LIJ2014-järjestelmän ajoneuvojen paikannuksen ja muiden työkalujen valmistumiseen. Johtoryhmän linjauksen mukaan kärkihankkeissa ja muissakin toimijoiden omissa hankkeissa syntyvien tietojärjestelmien rajapinnat avataan soveltuvasti kaupallisten toimijoiden käyttöön, jolloin syntyvien kaupallisten loppukäyttäjäpalveluiden kautta voidaan parantaa tietopalvelujen tavoittavuutta. Kärkihankkeiden valinta ja sisältö on rakennettu pitkälti sen lähtökohdan varaan, että liikenteen tietopalveluissa julkistoimijoiden roolina on pääasiassa lähtötietojen tuottaminen ja jakaminen varsinaisille palveluntuottajille. Vuoteen 2016 mennessä uusien rajapintojen kautta jaettavien tietojen määrä on nykyiseen verrattuna huomattavasti laajempi, ja odotukset uusien ja innovatiivisten palvelujen syntymiselle ovat korkeat. HLH-johtoryhmä nimeää jokaisen kärkihankkeen läpiviennistä vastaavan työryhmän, joiden työskentelyä ohjataan nykyisen kaltaisessa johtoryhmätyössä. Johtoryhmätyön organisointi on todettu toimivaksi, sillä ryhmä koostuu seudun 14 kunnan alueen keskeisistä julkisista toimijoista ja sen kautta on olemassa vahvat kytkennät sekä seudun liikennejärjestelmätyöhön (HLJ) että valtakunnalliseen älyliikenteen kehitystyöhön.

Exploration and Design of Power-Efficient Networked Many-Core Systems

Multiprocessing is a promising solution to meet the requirements of near future applications. To get full benefit from parallel processing, a manycore system needs efficient, on-chip communication architecture. Networkon- Chip (NoC) is a general purpose communication concept that offers highthroughput, reduced power consumption, and keeps complexity in check by a regular composition of basic building blocks. This thesis presents power efficient communication approaches for networked many-core systems. We address a range of issues being important for designing power-efficient manycore systems at two different levels: the network-level and the router-level. From the network-level point of view, exploiting state-of-the-art concepts such as Globally Asynchronous Locally Synchronous (GALS), Voltage/ Frequency Island (VFI), and 3D Networks-on-Chip approaches may be a solution to the excessive power consumption demanded by today’s and future many-core systems. To this end, a low-cost 3D NoC architecture, based on high-speed GALS-based vertical channels, is proposed to mitigate high peak temperatures, power densities, and area footprints of vertical interconnects in 3D ICs. To further exploit the beneficial feature of a negligible inter-layer distance of 3D ICs, we propose a novel hybridization scheme for inter-layer communication. In addition, an efficient adaptive routing algorithm is presented which enables congestion-aware and reliable communication for the hybridized NoC architecture. An integrated monitoring and management platform on top of this architecture is also developed in order to implement more scalable power optimization techniques. From the router-level perspective, four design styles for implementing power-efficient reconfigurable interfaces in VFI-based NoC systems are proposed. To enhance the utilization of virtual channel buffers and to manage their power consumption, a partial virtual channel sharing method for NoC routers is devised and implemented. Extensive experiments with synthetic and real benchmarks show significant power savings and mitigated hotspots with similar performance compared to latest NoC architectures. The thesis concludes that careful codesigned elements from different network levels enable considerable power savings for many-core systems.

Pipework data in design system integration

This thesis work describes the creation of a pipework data structure for design system integration. Work is completed in pulp and paper plant delivery company with global engineering network operations in mind. User case of process design to 3D pipework design is introduced with influence of subcontracting engineering offices. Company data element list is gathered by using key person interviews and results are processed into a pipework data element list. Inter-company co-operation is completed in standardization association and common standard for pipework data elements is found. As result inter-company created pipework data element list is introduced. Further list usage, development and relations to design software vendors are evaluated.

Validation of a 3D model for oxygen combustion in a circulating fluidized bed

In this thesis, a model called CFB3D is validated for oxygen combustion in circulating fluidized bed boiler. The first part of the work consists of literature review in which circulating fluidized bed and oxygen combustion technologies are studied. In addition, the modeling of circulating fluidized bed furnaces is discussed and currently available industrial scale three-dimensional furnace models are presented. The main features of CFB3D model are presented along with the theories and equations related to the model parameters used in this work. The second part of this work consists of the actual research and modeling work including measurements, model setup, and modeling results. The objectives of this thesis is to study how well CFB3D model works with oxygen combustion compared to air combustion in circulating fluidized bed boiler and what model parameters need to be adjusted when changing from air to oxygen combustion. The study is performed by modeling two air combustion cases and two oxygen combustion cases with comparable boiler loads. The cases are measured at Ciuden 30 MWth Flexi-Burn demonstration plant in April 2012. The modeled furnace temperatures match with the measurements as well in oxygen combustion cases as in air combustion cases but the modeled gas concentrations differ from the measurements clearly more in oxygen combustion cases. However, the same model parameters are optimal for both air and oxygen combustion cases. When the boiler load is changed, some combustion and heat transfer related model parameters need to be adjusted. To improve the accuracy of modeling results, better flow dynamics model should be developed in the CFB3D model. Additionally, more measurements are needed from the lower furnace to find the best model parameters for each case. The validation work needs to be continued in order to improve the modeling results and model predictability.

Simulointi- ja ohjausjärjestelmän kehitys siltanosturiavusteiseen automaattivarastoon

Diplomityö tehtiin Konecranes Oyj:lle, joka on nostureita valmistava ja niille kunnossapitopalveluita tarjoava suomalainen pörssiyhtiö. Työn kuluessa suunniteltiin ja toteutettiin siltanosturiavusteisiin automaattivarastoihin soveltuva simulointiohjelmisto ja varastonohjausjärjestelmä. Työssä keskityttiin pääsääntöisesti paperirullavarastoihin, mutta suunnitteluvaiheessa otettiin huomioon myös muut Konecranesin tarjontaan kuuluvat automaattivarastotyypit kuten vaakarulla ja kontti. Simulointiohjelmistolla mallinnetaan automaattivarastossa tapahtuvia liikkeitä. Käyttäjä pystyy näkemään nostureiden ja muiden varastossa olevien komponenttien liikkeet 3D- muotoisena simulaattorin käyttöliittymästä. Simulaattorin tavoitteena on helpottaa automaattivaraston suunnittelua ja nopeuttaa sen käyttöönottoa, sekä toimia myös vakuuttavana myyntityökaluna asiakaskontakteissa. Varastonohjausjärjestelmä tekee päätökset varaston tapahtumista ja ohjaa mm. nostureiden toimintaa. Diplomityön päämääränä oli perehtyä tarkasti nykyisen varastonohjausjärjestelmän toimintaan, kehittää uusi ratkaisumalli puutteiden sekä toiveiden perusteella ja lopulta osoittaa ratkaisumallin toimivuus ohjelmoimalla esittelyversio simulaattorista ja varastonohjausjärjestelmästä. Samaa varastonohjausjärjestelmää on määrä käyttää simulaattorissa ja tulevaisuudessa todellisen varaston ohjaamisessa. Asetetuista vaatimuksista johtuen järjestelmästä suunniteltiin mahdollisimman mukautuva. Työn lopputuloksena saatiin perusominaisuudet kattava 3D-simulaattori ja siihen liitetty varastonohjausjärjestelmä. Toteutuksen avulla oli mahdollista osoittaa ratkaisumallin toimivuus sekä esitellä ideaa laajamittaisemmin. Diplomityön kuluessa saatiin nykyisestä järjestelmästä kattavat tiedot ja pystyttiin määräämään suunta, kuinka kehitystyötä jatketaan.

Tietokantojen yhdistäminen järjestelmän rajapintoja hyödyntäen

Tässä työssä on pyritty kartoittamaan mahdollisuudet omatoimiseen Voyager-kirjastojärjestelmän aineistotietokantojen ja asiakasrekisterien yhdistelyyn. Lähtökohtana on ollut oletus, että kohdejärjestelmän tietokantaan ei ole oikeuksia eikä sopimusteknistä mahdollisuuttakaan kirjoittaa tietoja suoraan kyselykielellä. Järjestelmän dokumentaatiota sekä verkostoa hyödyntämällä olen pyrkinyt kartoittamaan mahdollisuudet kaiken toiminnallisuuden vaatiman datan siirtoon. Hyödyntämällä järjestelmän rajapintoja, voidaan saavuttaa kustannussäästöjä sekä joustavuutta työn suorittamisen aikataulutukseen. Bibliografisen datan siirtoon Voyager-kirjastojärjestelmässä on mahdollisuus hyödyntää palvelimella eräajona suoritettavaa ohjelmaa. Tässä eräajossa voidaan siirtää sekä bibliografiset tietueet että varastotietueet. Nidetietojen kirjoittamiseksi kohteena olevaan tietokantaan käytetään Visual Studio -sovellusta, joka hyödyntää luettelointirajapintaa. Asiakastietojen siirtoon on mahdollista hyödyntää palvelimella suoritettavaa eräajoa, jonka syötteeksi kirjoitetaan määrämittainen syötetiedosto. Asiakastietueisiin sidotut lainatiedot voidaan siirtää kohdetietokantaan asiakasohjelman offline-lainaustoiminnolla.

Prediction of 3D structure and ligand-binding properties : ABC transporters and flavodiiron proteins from Synechocystis sp. strain PCC 6803

Cyanobacteria are unicellular, non-nitrogen-fixing prokaryotes, which perform photosynthesis similarly as higher plants. The cyanobacterium Synechocystis sp. strain PCC 6803 is used as a model organism in photosynthesis research. My research described herein aims at understanding the function of the photosynthetic machinery and how it responds to changes in the environment. Detailed knowledge of the regulation of photosynthesis in cyanobacteria can be utilized for biotechnological purposes, for example in the harnessing of solar energy for biofuel production. In photosynthesis, iron participates in electron transfer. Here, we focused on iron transport in Synechocystis sp. strain PCC 6803 and particularly on the environmental regulation of the genes encoding the FutA2BC ferric iron transporter, which belongs to the ABC transporter family. A homology model built for the ATP-binding subunit FutC indicates that it has a functional ATPbinding site as well as conserved interactions with the channel-forming subunit FutB in the transporter complex. Polyamines are important for the cell proliferation, differentiation and apoptosis in prokaryotic and eukaryotic cells. In plants, polyamines have special roles in stress response and in plant survival. The polyamine metabolism in cyanobacteria in response to environmental stress is of interest in research on stress tolerance of higher plants. In this thesis, the potd gene encoding an polyamine transporter subunit from Synechocystis sp. strain PCC 6803 was characterized for the first time. A homology model built for PotD protein indicated that it has capability of binding polyamines, with the preference for spermidine. Furthermore, in order to investigate the structural features of the substrate specificity, polyamines were docked into the binding site. Spermidine was positioned very similarly in Synechocystis PotD as in the template structure and had most favorable interactions of the docked polyamines. Based on the homology model, experimental work was conducted, which confirmed the binding preference. Flavodiiron proteins (Flv) are enzymes, which protect the cell against toxicity of oxygen and/or nitric oxide by reduction. In this thesis, we present a novel type of photoprotection mechanism in cyanobacteria by the heterodimer of Flv2/Flv4. The constructed homology model of Flv2/Flv4 suggests a functional heterodimer capable of rapid electron transfer. The unknown protein sll0218, encoded by the flv2-flv4 operon, is assumed to facilitate the interaction of the Flv2/Flv4 heterodimer and energy transfer between the phycobilisome and PSII. Flv2/Flv4 provides an alternative electron transfer pathway and functions as an electron sink in PSII electron transfer.