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This article briefly reviews the composition of the hyaline cartilage and its ultrastructure. Subsequently, we offer a brief review of the role of imaging techniques in the assessment of this pathology. These include the most useful pulse sequences for the morphological assessment of cartilaginous injuries using MRI, as well as how these injuries appear in the images, at pre and post-surgical intervals. Lastly, we mention the developments in MRI that allow us to close in on the biochemical assessment of normal and pathological cartilage.