2 resultados para tecnologías digitales CAD-CAM-CAE

em Université de Lausanne, Switzerland


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Im August 2012 brachte der Heimatverein von Borja, in Spanien, auf seinem Blog seine »tiefe Betroffenheit« über einen, wie es hieß, »unbeschreiblichen Vorgang« zum Ausdruck: Ein Wandgemälde in der Iglesia del Santuario de la Misericordia war in einer Form restauriert worden, die das ursprüngliche Motiv - den Schmerzensmann - fast unkenntlich machte. Die Affäre ging in kürzester Zeit durch die internationale Presse und durch das Internet. Sie schlug dabei unerwartet hohe Wellen, mit denen sich Hohn und Spott über den in fast allen Kommentaren als »misslungen« bezeichneten Restaurierungsakt ergoss. Im Web 2.0 hingegen gab das dergestalt »restaurierte« Antlitz des Ecce homo Anlass zu einer Vielzahl von Neuinterpretationen, es avancierte zu einem regelrechten Internet-Phänomen, das in der vorliegenden Studie in Hinblick auf den Umgang mit und die Aneignung von Bildern im digitalen Zeitalter untersucht werden soll.

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Background: The public health burden of coronary artery disease (CAD) is important. Perfusion cardiac magnetic resonance (CMR) is generally accepted to detect and monitor CAD. Few studies have so far addressed its costs and costeffectiveness. Objectives: To compare in a large CMR registry the costs of a CMR-guided strategy vs two hypothetical invasive strategies for the diagnosis and the treatment of patients with suspected CAD. Methods: In 3'647 patients with suspected CAD included prospectively in the EuroCMR Registry (59 centers; 18 countries) costs were calculated for diagnostic examinations, revascularizations as well as for complication management over a 1-year follow-up. Patients with ischemia-positive CMR underwent an invasive X-ray coronary angiography (CXA) and revascularization at the discretion of the treating physician (=CMR+CXA strategy). Ischemia was found in 20.9% of patients and 17.4% of them were revascularized. In ischemia-negative patients by CMR, cardiac death and non-fatal myocardial infarctions occurred in 0.38%/y. In a hypothetical invasive arm the costs were calculated for an initial CXA followed by FFR testing in vessels with ≥50% diameter stenoses (=CXA+FFR strategy). To model this hypothetical arm, the same proportion of ischemic patients and outcome was assumed as for the CMR+CXA strategy. The coronary stenosis - FFR relationship reported in the literature was used to derive the proportion of patients with ≥50% diameter stenoses (Psten) in the study cohort. The costs of a CXA-only strategy were also calculated. Calculations were performed from a third payer perspective for the German, UK, Swiss, and US healthcare systems.