1 resultado para Virginia--History--Colonial period, ca. 1600-1775
em Université de Lausanne, Switzerland
Filtro por publicador
- University of Cagliari UniCA Eprints (1)
- Aberystwyth University Repository - Reino Unido (2)
- Academic Research Repository at Institute of Developing Economies (1)
- Acceda, el repositorio institucional de la Universidad de Las Palmas de Gran Canaria. España (1)
- Adam Mickiewicz University Repository (2)
- AMS Tesi di Dottorato - Alm@DL - Università di Bologna (3)
- AMS Tesi di Laurea - Alm@DL - Università di Bologna (1)
- Andina Digital - Repositorio UASB-Digital - Universidade Andina Simón Bolívar (46)
- Aquatic Commons (65)
- ArchiMeD - Elektronische Publikationen der Universität Mainz - Alemanha (1)
- Biblioteca Digital | Sistema Integrado de Documentación | UNCuyo - UNCUYO. UNIVERSIDAD NACIONAL DE CUYO. (3)
- Biblioteca Digital da Câmara dos Deputados (1)
- Biblioteca Digital da Produção Intelectual da Universidade de São Paulo (2)
- Biblioteca Digital da Produção Intelectual da Universidade de São Paulo (BDPI/USP) (1)
- Biblioteca Digital de la Universidad Católica Argentina (3)
- Biblioteca Digital de Teses e Dissertações Eletrônicas da UERJ (14)
- Biodiversity Heritage Library, United States (1)
- BORIS: Bern Open Repository and Information System - Berna - Suiça (28)
- Boston University Digital Common (1)
- Brock University, Canada (14)
- Bucknell University Digital Commons - Pensilvania - USA (1)
- Bulgarian Digital Mathematics Library at IMI-BAS (2)
- CaltechTHESIS (1)
- CentAUR: Central Archive University of Reading - UK (2)
- Center for Jewish History Digital Collections (4)
- Chapman University Digital Commons - CA - USA (12)
- Chinese Academy of Sciences Institutional Repositories Grid Portal (8)
- Comissão Econômica para a América Latina e o Caribe (CEPAL) (1)
- CORA - Cork Open Research Archive - University College Cork - Ireland (8)
- Dalarna University College Electronic Archive (1)
- Deakin Research Online - Australia (11)
- Digital Commons - Montana Tech (1)
- Digital Commons @ DU | University of Denver Research (2)
- Digital Commons at Florida International University (4)
- Digitale Sammlungen - Goethe-Universität Frankfurt am Main (2)
- DRUM (Digital Repository at the University of Maryland) (3)
- Duke University (6)
- eResearch Archive - Queensland Department of Agriculture; Fisheries and Forestry (4)
- Fachlicher Dokumentenserver Paedagogik/Erziehungswissenschaften (1)
- Glasgow Theses Service (2)
- Greenwich Academic Literature Archive - UK (2)
- Harvard University (25)
- Helda - Digital Repository of University of Helsinki (14)
- Indian Institute of Science - Bangalore - Índia (3)
- Institutional Repository of Leibniz University Hannover (1)
- Instituto Politécnico do Porto, Portugal (3)
- Memoria Académica - FaHCE, UNLP - Argentina (62)
- Plymouth Marine Science Electronic Archive (PlyMSEA) (1)
- Portal de Revistas Científicas Complutenses - Espanha (7)
- Publishing Network for Geoscientific & Environmental Data (15)
- QSpace: Queen's University - Canada (1)
- QUB Research Portal - Research Directory and Institutional Repository for Queen's University Belfast (59)
- Queensland University of Technology - ePrints Archive (37)
- Repositorio Académico de la Universidad Nacional de Costa Rica (4)
- Repositório Científico da Universidade de Évora - Portugal (3)
- Repositorio de la Universidad de Cuenca (1)
- Repositório digital da Fundação Getúlio Vargas - FGV (3)
- Repositório Institucional da Universidade de Aveiro - Portugal (3)
- Repositório Institucional da Universidade de Brasília (1)
- Repositório Institucional da Universidade Estadual de São Paulo - UNESP (1)
- Repositório Institucional da Universidade Federal do Rio Grande do Norte (2)
- Repositório Institucional UNESP - Universidade Estadual Paulista "Julio de Mesquita Filho" (36)
- Royal College of Art Research Repository - Uninet Kingdom (1)
- RUN (Repositório da Universidade Nova de Lisboa) - FCT (Faculdade de Cienecias e Technologia), Universidade Nova de Lisboa (UNL), Portugal (1)
- Savoirs UdeS : plateforme de diffusion de la production intellectuelle de l’Université de Sherbrooke - Canada (2)
- South Carolina State Documents Depository (2)
- Universidad de Alicante (1)
- Universidad del Rosario, Colombia (5)
- Universidad Politécnica de Madrid (2)
- Universidade de Lisboa - Repositório Aberto (4)
- Universidade Federal do Pará (14)
- Universidade Federal do Rio Grande do Norte (UFRN) (5)
- Universidade Metodista de São Paulo (1)
- Universitat de Girona, Spain (1)
- Université de Lausanne, Switzerland (1)
- Université de Montréal, Canada (18)
- Université Laval Mémoires et thèses électroniques (1)
- University of Connecticut - USA (1)
- University of Michigan (327)
- University of Queensland eSpace - Australia (4)
- University of Washington (2)
- USA Library of Congress (2)
- WestminsterResearch - UK (2)
- Worcester Research and Publications - Worcester Research and Publications - UK (1)
Resumo:
Mitochondria have a fundamental role in the transduction of energy from food into ATP. The coupling between food oxidation and ATP production is never perfect, but may nevertheless be of evolutionary significance. The 'uncoupling to survive' hypothesis suggests that 'mild' mitochondrial uncoupling evolved as a protective mechanism against the excessive production of damaging reactive oxygen species (ROS). Because resource allocation and ROS production are thought to shape animal life histories, alternative life-history trajectories might be driven by individual variation in the degree of mitochondrial uncoupling. We tested this hypothesis in a small bird species, the zebra finch (Taeniopygia guttata), by treating adults with the artificial mitochondrial uncoupler 2,4-dinitrophenol (DNP) over a 32-month period. In agreement with our expectations, the uncoupling treatment increased metabolic rate. However, we found no evidence that treated birds enjoyed lower oxidative stress levels or greater survival rates, in contrast to previous results in other taxa. In vitro experiments revealed lower sensitivity of ROS production to DNP in mitochondria isolated from skeletal muscles of zebra finch than mouse. In addition, we found significant reductions in the number of eggs laid and in the inflammatory immune response in treated birds. Altogether, our data suggest that the 'uncoupling to survive' hypothesis may not be applicable for zebra finches, presumably because of lower effects of mitochondrial uncoupling on mitochondrial ROS production in birds than in mammals. Nevertheless, mitochondrial uncoupling appeared to be a potential life-history regulator of traits such as fecundity and immunity at adulthood, even with food supplied ad libitum.