1 resultado para SENSORY PHENOMENA
em Université de Lausanne, Switzerland
Filtro por publicador
- ABACUS. Repositorio de Producción Científica - Universidad Europea (1)
- Aberdeen University (1)
- Aberystwyth University Repository - Reino Unido (5)
- Acceda, el repositorio institucional de la Universidad de Las Palmas de Gran Canaria. España (1)
- Adam Mickiewicz University Repository (1)
- AMS Tesi di Dottorato - Alm@DL - Università di Bologna (13)
- Aquatic Commons (10)
- ArchiMeD - Elektronische Publikationen der Universität Mainz - Alemanha (5)
- Archimer: Archive de l'Institut francais de recherche pour l'exploitation de la mer (1)
- Archivo Digital para la Docencia y la Investigación - Repositorio Institucional de la Universidad del País Vasco (2)
- Aston University Research Archive (44)
- Biblioteca de Teses e Dissertações da USP (1)
- Biblioteca Digital | Sistema Integrado de Documentación | UNCuyo - UNCUYO. UNIVERSIDAD NACIONAL DE CUYO. (1)
- Biblioteca Digital da Produção Intelectual da Universidade de São Paulo (11)
- Biblioteca Digital da Produção Intelectual da Universidade de São Paulo (BDPI/USP) (6)
- Biblioteca Digital de Teses e Dissertações Eletrônicas da UERJ (1)
- Biodiversity Heritage Library, United States (3)
- Bioline International (1)
- BORIS: Bern Open Repository and Information System - Berna - Suiça (60)
- Boston University Digital Common (7)
- Brock University, Canada (5)
- Bucknell University Digital Commons - Pensilvania - USA (1)
- Bulgarian Digital Mathematics Library at IMI-BAS (3)
- CaltechTHESIS (10)
- Cambridge University Engineering Department Publications Database (49)
- CentAUR: Central Archive University of Reading - UK (68)
- Chinese Academy of Sciences Institutional Repositories Grid Portal (37)
- Cochin University of Science & Technology (CUSAT), India (4)
- Comissão Econômica para a América Latina e o Caribe (CEPAL) (1)
- CORA - Cork Open Research Archive - University College Cork - Ireland (3)
- Corvinus Research Archive - The institutional repository for the Corvinus University of Budapest (1)
- CUNY Academic Works (1)
- Deakin Research Online - Australia (75)
- DI-fusion - The institutional repository of Université Libre de Bruxelles (1)
- Digital Commons - Michigan Tech (2)
- Digital Commons at Florida International University (6)
- Digital Howard @ Howard University | Howard University Research (1)
- DigitalCommons@The Texas Medical Center (24)
- Diposit Digital de la UB - Universidade de Barcelona (2)
- Doria (National Library of Finland DSpace Services) - National Library of Finland, Finland (1)
- Duke University (7)
- eResearch Archive - Queensland Department of Agriculture; Fisheries and Forestry (13)
- eScholarship Repository - University of California (2)
- Greenwich Academic Literature Archive - UK (16)
- Helda - Digital Repository of University of Helsinki (8)
- Illinois Digital Environment for Access to Learning and Scholarship Repository (2)
- Indian Institute of Science - Bangalore - Índia (37)
- INSTITUTO DE PESQUISAS ENERGÉTICAS E NUCLEARES (IPEN) - Repositório Digital da Produção Técnico Científica - BibliotecaTerezine Arantes Ferra (3)
- Instituto Politécnico de Viseu (1)
- Instituto Politécnico do Porto, Portugal (11)
- Ministerio de Cultura, Spain (1)
- National Center for Biotechnology Information - NCBI (40)
- Nottingham eTheses (2)
- Plymouth Marine Science Electronic Archive (PlyMSEA) (3)
- Publishing Network for Geoscientific & Environmental Data (2)
- QUB Research Portal - Research Directory and Institutional Repository for Queen's University Belfast (57)
- Queensland University of Technology - ePrints Archive (39)
- Repositório Alice (Acesso Livre à Informação Científica da Embrapa / Repository Open Access to Scientific Information from Embrapa) (6)
- Repositório Científico da Universidade de Évora - Portugal (4)
- Repositório Institucional da Universidade de Aveiro - Portugal (3)
- Repositório Institucional UNESP - Universidade Estadual Paulista "Julio de Mesquita Filho" (78)
- Research Open Access Repository of the University of East London. (3)
- RUN (Repositório da Universidade Nova de Lisboa) - FCT (Faculdade de Cienecias e Technologia), Universidade Nova de Lisboa (UNL), Portugal (2)
- SAPIENTIA - Universidade do Algarve - Portugal (2)
- Savoirs UdeS : plateforme de diffusion de la production intellectuelle de l’Université de Sherbrooke - Canada (1)
- School of Medicine, Washington University, United States (10)
- Universidad Autónoma de Nuevo León, Mexico (1)
- Universidad de Alicante (2)
- Universidad Politécnica de Madrid (10)
- Universidade Complutense de Madrid (4)
- Universidade de Lisboa - Repositório Aberto (1)
- Universidade do Algarve (2)
- Universidade Técnica de Lisboa (1)
- Universitat de Girona, Spain (1)
- Universitätsbibliothek Kassel, Universität Kassel, Germany (1)
- Université de Lausanne, Switzerland (1)
- Université de Montréal (1)
- Université de Montréal, Canada (5)
- University of Canberra Research Repository - Australia (1)
- University of Connecticut - USA (2)
- University of Michigan (80)
- University of Queensland eSpace - Australia (33)
- University of Southampton, United Kingdom (2)
- University of Washington (2)
- WestminsterResearch - UK (2)
Resumo:
Electrical neuromodulation of lumbar segments improves motor control after spinal cord injury in animal models and humans. However, the physiological principles underlying the effect of this intervention remain poorly understood, which has limited the therapeutic approach to continuous stimulation applied to restricted spinal cord locations. Here we developed stimulation protocols that reproduce the natural dynamics of motoneuron activation during locomotion. For this, we computed the spatiotemporal activation pattern of muscle synergies during locomotion in healthy rats. Computer simulations identified optimal electrode locations to target each synergy through the recruitment of proprioceptive feedback circuits. This framework steered the design of spatially selective spinal implants and real-time control software that modulate extensor and flexor synergies with precise temporal resolution. Spatiotemporal neuromodulation therapies improved gait quality, weight-bearing capacity, endurance and skilled locomotion in several rodent models of spinal cord injury. These new concepts are directly translatable to strategies to improve motor control in humans.