1 resultado para Cucumber Mosaic Cucumovirus
em Université de Lausanne, Switzerland
Filtro por publicador
- Acceda, el repositorio institucional de la Universidad de Las Palmas de Gran Canaria. España (5)
- Adam Mickiewicz University Repository (1)
- AMS Tesi di Dottorato - Alm@DL - Università di Bologna (14)
- AMS Tesi di Laurea - Alm@DL - Università di Bologna (1)
- Aquatic Commons (25)
- ArchiMeD - Elektronische Publikationen der Universität Mainz - Alemanha (8)
- Archimer: Archive de l'Institut francais de recherche pour l'exploitation de la mer (1)
- Aston University Research Archive (2)
- Avian Conservation and Ecology - Eletronic Cientific Hournal - Écologie et conservation des oiseaux: (1)
- Biblioteca de Teses e Dissertações da USP (1)
- Biblioteca Digital | Sistema Integrado de Documentación | UNCuyo - UNCUYO. UNIVERSIDAD NACIONAL DE CUYO. (3)
- Biblioteca Digital da Produção Intelectual da Universidade de São Paulo (20)
- Biblioteca Digital da Produção Intelectual da Universidade de São Paulo (BDPI/USP) (14)
- Biblioteca Digital de Teses e Dissertações Eletrônicas da UERJ (8)
- Bibloteca do Senado Federal do Brasil (1)
- BORIS: Bern Open Repository and Information System - Berna - Suiça (28)
- Boston University Digital Common (4)
- Brock University, Canada (8)
- Bucknell University Digital Commons - Pensilvania - USA (2)
- CaltechTHESIS (3)
- Cambridge University Engineering Department Publications Database (3)
- CentAUR: Central Archive University of Reading - UK (26)
- Center for Jewish History Digital Collections (1)
- Chinese Academy of Sciences Institutional Repositories Grid Portal (72)
- Cochin University of Science & Technology (CUSAT), India (1)
- Comissão Econômica para a América Latina e o Caribe (CEPAL) (1)
- Deakin Research Online - Australia (58)
- Department of Computer Science E-Repository - King's College London, Strand, London (1)
- DI-fusion - The institutional repository of Université Libre de Bruxelles (6)
- Digital Commons - Michigan Tech (2)
- Digital Commons @ DU | University of Denver Research (1)
- Digital Commons at Florida International University (1)
- Digital Repository at Iowa State University (4)
- DigitalCommons - The University of Maine Research (2)
- DigitalCommons@The Texas Medical Center (4)
- DigitalCommons@University of Nebraska - Lincoln (2)
- Digitale Sammlungen - Goethe-Universität Frankfurt am Main (1)
- DRUM (Digital Repository at the University of Maryland) (4)
- Duke University (2)
- eResearch Archive - Queensland Department of Agriculture; Fisheries and Forestry (21)
- FAUBA DIGITAL: Repositorio institucional científico y académico de la Facultad de Agronomia de la Universidad de Buenos Aires (1)
- Greenwich Academic Literature Archive - UK (1)
- Helda - Digital Repository of University of Helsinki (10)
- Indian Institute of Science - Bangalore - Índia (46)
- Infoteca EMBRAPA (3)
- Instituto Politécnico do Porto, Portugal (1)
- Massachusetts Institute of Technology (1)
- Ministerio de Cultura, Spain (2)
- National Center for Biotechnology Information - NCBI (41)
- Plymouth Marine Science Electronic Archive (PlyMSEA) (1)
- Portal de Revistas Científicas Complutenses - Espanha (1)
- Publishing Network for Geoscientific & Environmental Data (32)
- QSpace: Queen's University - Canada (1)
- QUB Research Portal - Research Directory and Institutional Repository for Queen's University Belfast (25)
- Queensland University of Technology - ePrints Archive (50)
- RDBU - Repositório Digital da Biblioteca da Unisinos (1)
- ReCiL - Repositório Científico Lusófona - Grupo Lusófona, Portugal (1)
- Repositório Alice (Acesso Livre à Informação Científica da Embrapa / Repository Open Access to Scientific Information from Embrapa) (6)
- Repositório digital da Fundação Getúlio Vargas - FGV (2)
- Repositorio Institucional da UFLA (RIUFLA) (1)
- Repositório Institucional da Universidade de Aveiro - Portugal (3)
- Repositorio Institucional de la Universidad Nacional Agraria (2)
- Repositório Institucional UNESP - Universidade Estadual Paulista "Julio de Mesquita Filho" (272)
- Research Open Access Repository of the University of East London. (2)
- RUN (Repositório da Universidade Nova de Lisboa) - FCT (Faculdade de Cienecias e Technologia), Universidade Nova de Lisboa (UNL), Portugal (1)
- SAPIENTIA - Universidade do Algarve - Portugal (9)
- Universidad de Alicante (1)
- Universidad del Rosario, Colombia (7)
- Universidad Politécnica de Madrid (23)
- Universidade Complutense de Madrid (1)
- Universidade de Lisboa - Repositório Aberto (1)
- Universidade Federal do Pará (6)
- Universidade Federal do Rio Grande do Norte (UFRN) (9)
- Universitat de Girona, Spain (14)
- Universitätsbibliothek Kassel, Universität Kassel, Germany (1)
- Université de Lausanne, Switzerland (1)
- Université de Montréal, Canada (10)
- University of Connecticut - USA (1)
- University of Michigan (21)
- University of Queensland eSpace - Australia (7)
- University of Southampton, United Kingdom (1)
Resumo:
Adult neurogenesis is regulated by the neurogenic niche, through mechanisms that remain poorly defined. Here, we investigated whether niche-constituting astrocytes influence the maturation of adult-born hippocampal neurons using two independent transgenic approaches to block vesicular release from astrocytes. In these models, adult-born neurons but not mature neurons showed reduced glutamatergic synaptic input and dendritic spine density that was accompanied with lower functional integration and cell survival. By taking advantage of the mosaic expression of transgenes in astrocytes, we found that spine density was reduced exclusively in segments intersecting blocked astrocytes, revealing an extrinsic, local control of spine formation. Defects in NMDA receptor (NMDAR)-mediated synaptic transmission and dendrite maturation were partially restored by exogenous D-serine, whose extracellular level was decreased in transgenic models. Together, these results reveal a critical role for adult astrocytes in local dendritic spine maturation, which is necessary for the NMDAR-dependent functional integration of newborn neurons.