El Periodisme esportiu i els gèneres periodístics: una anàlisi quantitativa a partir d'un corpus de premsa catalana i espanyola d'informació general

Prenent com a marc el món de l’esport i la premsa d'informació general amb presència a Catalunya, el present treball es proposa investigar quina cobertura dóna aquest tipus de premsa a l’esport en general i al futbol en particular. Per a dur a terme aquesta tasca ens centrarem en la utilització dels gèneres periodístics en la redacció dels textos

Sociedades cooperativas: mercantilidad y operaciones con terceros. Un comentario

En este trabajo se hace referencia a la posible consideración de las sociedades cooperativas como sociedades mercantiles, cumpliéndose determinadas circunstancias, y ello sin pérdida de sus características específicas en cuanto a la toma de decisiones, el reparto de beneficios y la búsqueda de la satisfacción de fines de interés general. Asimismo, se analizan las consecuencias de aumentar el porcentaje de operaciones realizadas con terceros no socios, respecto del total de operaciones realizadas por la sociedad cooperativa, y su incidencia en la cuantía de los fondos de la cooperativa y en la retribución del socio cooperativista. Se realiza en este punto una comparación con las sociedades capitalistas convencionales (S.A., S.L.). Finalmente, se propone una reforma legislativa al objeto de permitir aumentar el porcentaje de realización de operaciones cooperativizadas con terceros no socios, y ello sin pérdida de su tratamiento fiscal favorable. PALABRAS CLAVE: Cooperativas, mercantilidad, mutualismo, operaciones con terceros, régimen fiscal, reformas legislativas. CLAVES ECONLIT: P130, Q130, L310

RNA interference: a new and powerful tool for functional genomic analysis.

In many species, the introduction of double-stranded RNA induces potent and specific gene silencing, referred to as RNA interference. This phenomenon, which is based on targeted degradation of mRNAs and occurs in almost any eukaryote, from trypanosomes to mice including plants and fungi, has sparked general interest from both applied and fundamental standpoints. RNA interference, which is currently used to investigate gene function in a variety of systems, is linked to natural resistance to viruses and transposon silencing, as if it were a primitive immune system involved in genome surveillance. Here, we review the mechanism of RNA interference in post-transcriptional gene silencing, its function in nature, its value for functional genomic analysis, and the modifications and improvements that may make it more efficient and inheritable. We also discuss the future directions of this versatile technique in both fundamental and applied science.

Satisfaction survey with DNA cards method to collect genetic samples for pharmacogenetics studies

Background: Pharmacogenetic studies are essential in understanding the interindividual variability of drug responses. DNA sample collection for genotyping is a critical step in genetic studies. A method using dried blood samples from finger-puncture, collected on DNA-cards, has been described as an alternative to the usual venepuncture technique. The purpose of this study is to evaluate the implementation of the DNA cards method in a multicentre clinical trial, and to assess the degree of investigators' satisfaction and the acceptance of the patients perceived by the investigators.Methods: Blood samples were collected on DNA-cards. The quality and quantity of DNA recovered were analyzed. Investigators were questioned regarding their general interest, previous experience, safety issues, preferences and perceived patient satisfaction. Results: 151 patients' blood samples were collected. Genotyping of GST polymorphisms was achieved in all samples (100%). 28 investigators completed the survey. Investigators perceived patient satisfaction as very good (60.7%) or good (39.3%), without reluctance to finger puncture. Investigators preferred this method, which was considered safer and better than the usual methods. All investigators would recommend using it in future genetic studies. Conclusion: Within the clinical trial setting, the DNA-cards method was very well accepted by investigators and patients (in perception of investigators), and was preferred to conventional methods due to its ease of use and safety.

Análisis y creación de un sistema informático de soporte a entidades sanitarias para la detección precoz de brotes de gripe en épocas de máximo riesgo.

Hoy en día, las posibilidades del Big Data son incontables. Existe gran cantidad de información generada por la población general y disponible de forma pública.El reto consiste en poder trabajar con esta información y extraer conclusiones útiles y que generen valor.En este proyecto, queremos analizar en el tiempo el interés general de la población respecto a una enfermedad común como la gripe, y poder relacionarlos con brotes de gripe existentes en el pasado, para de esta manera, poder extrapolar y predecir futuros brotes.Esta información, en manos de las autoridades sanitarias, puede ser de gran ayuda para poder prevenir picos de solicitudes en los servicios de urgencias, anticipándose para gestionar de manera más eficaz los recursos disponibles, consiguiendo, de esta manera, un mejor servicio a la población en general.De esta manera, son los propios usuarios los que, sin saberlo, posibilitan una mayor y mejor respuesta en los servicios sanitarios mediante la información que ellos mismos distribuyen libremente, consiguiéndose de esta manera valiosos beneficios para la población general.

Análisis y creación de un sistema informático de soporte a entidades sanitarias para la detección precoz de brotes de gripe en épocas de máximo riesgo

En este proyecto queremos analizar en el tiempo el interés general de la población respecto a una enfermedad común como la gripe, y poder relacionarlos con brotes de gripe existentes en el pasado, para de esta manera, poder extrapolar y predecir futuros brotes. Esta información, en manos de las autoridades sanitarias, puede ser de gran ayuda para poder prevenir picos de solicitudes en los servicios de urgencias, anticipándose para gestionar de manera más eficaz los recursos disponibles, consiguiendo, de esta manera, un mejor servicio a la población en general.

Counter-propagating dual-trap optical tweezers based on linear momentum conservation

We present a dual-trap optical tweezers setup which directly measures forces using linear momentum conservation. The setup uses a counter-propagating geometry, which allows momentum measurement on each beam separately. The experimental advantages of this setup include low drift due to all-optical manipulation, and a robust calibration (independent of the features of the trapped object or buffer medium) due to the force measurement method. Although this design does not attain the high-resolution of some co-propagating setups, we show that it can be used to perform different single molecule measurements: fluctuation-based molecular stiffness characterization at different forces and hopping experiments on molecular hairpins. Remarkably, in our setup it is possible to manipulate very short tethers (such as molecular hairpins with short handles) down to the limit where beads are almost in contact. The setup is used to illustrate a novel method for measuring the stiffness of optical traps and tethers on the basis of equilibrium force fluctuations, i.e., without the need of measuring the force vs molecular extension curve. This method is of general interest for dual trap optical tweezers setups and can be extended to setups which do not directly measure forces.

A two-mean reverting-factor model of the term structure of interest rates

This paper presents a two--factor model of the term structure ofinterest rates. We assume that default free discount bond prices aredetermined by the time to maturity and two factors, the long--term interestrate and the spread (difference between the long--term rate and theshort--term (instantaneous) riskless rate). Assuming that both factorsfollow a joint Ornstein--Uhlenbeck process, a general bond pricing equationis derived. We obtain a closed--form expression for bond prices andexamine its implications for the term structure of interest rates. We alsoderive a closed--form solution for interest rate derivatives prices. Thisexpression is applied to price European options on discount bonds andmore complex types of options. Finally, empirical evidence of the model'sperformance is presented.

General method to determine replica symmetry breaking transitions

We introduce a new parameter to investigate replica symmetry breaking transitions using finite-size scaling methods. Based on exact equalities initially derived by F. Guerra this parameter is a direct check of the self-averaging character of the spin-glass order parameter. This new parameter can be used to study models with time reversal symmetry but its greatest interest lies in models where this symmetry is absent. We apply the method to long-range and short-range Ising spin-glasses with and without a magnetic field as well as short-range multispin interaction spin-glasses.