EURECCA colorectal: multidisciplinary mission statement on better care for patients with colon and rectal cancer in Europe

Background: Care for patients with colon and rectal cancer has improved in the last twenty years however still considerable variation exists in cancer management and outcome between European countries. Therefore, EURECCA, which is the acronym of European Registration of cancer care, is aiming at defining core treatment strategies and developing a European audit structure in order to improve the quality of care for all patients with colon and rectal cancer. In December 2012 the first multidisciplinary consensus conference about colon and rectum was held looking for multidisciplinary consensus. The expert panel consisted of representatives of European scientific organisations involved in cancer care of patients with colon and rectal cancer and representatives of national colorectal registries. Methods: The expert panel had delegates of the European Society of Surgical Oncology (ESSO), European Society for Radiotherapy & Oncology (ESTRO), European Society of Pathology (ESP), European Society for Medical Oncology (ESMO), European Society of Radiology (ESR), European Society of Coloproctology (ESCP), European CanCer Organisation (ECCO), European Oncology Nursing Society (EONS) and the European Colorectal Cancer Patient Organisation (EuropaColon), as well as delegates from national registries or audits. Experts commented and voted on the two web-based online voting rounds before the meeting (between 4th and 25th October and between the 20th November and 3rd December 2012) as well as one online round after the meeting (4th20th March 2013) and were invited to lecture on the subjects during the meeting (13th15th December 2012). The sentences in the consensus document were available during the meeting and a televoting round during the conference by all participants was performed. All sentences that were voted on are available on the EURECCA website www.canceraudit.eu. The consensus document was divided in sections describing evidence based algorithms of diagnostics, pathology, surgery, medical oncology, radiotherapy, and follow-up where applicable for treatment of colon cancer, rectal cancer and stage IV separately. Consensus was achieved using the Delphi method. Results: The total number of the voted sentences was 465. All chapters were voted on by at least 75% of the experts. Of the 465 sentences, 84% achieved large consensus, 6% achieved moderate consensus, and 7% resulted in minimum consensus. Only 3% was disagreed by more than 50% of the members. Conclusions: It is feasible to achieve European Consensus on key diagnostic and treatment issues using the Delphi method. This consensus embodies the expertise of professionals from all disciplines involved in the care for patients with colon and rectal cancer. Diagnostic and treatment algorithms were developed to implement the current evidence and to define core treatment guidance for multidisciplinary team management of colon and rectal cancer throughout Europe.

EURECCA colorectal: multidisciplinary mission statement on better care for patients with colon and rectal cancer in Europe

Background: Care for patients with colon and rectal cancer has improved in the last twenty years however still considerable variation exists in cancer management and outcome between European countries. Therefore, EURECCA, which is the acronym of European Registration of cancer care, is aiming at defining core treatment strategies and developing a European audit structure in order to improve the quality of care for all patients with colon and rectal cancer. In December 2012 the first multidisciplinary consensus conference about colon and rectum was held looking for multidisciplinary consensus. The expert panel consisted of representatives of European scientific organisations involved in cancer care of patients with colon and rectal cancer and representatives of national colorectal registries. Methods: The expert panel had delegates of the European Society of Surgical Oncology (ESSO), European Society for Radiotherapy & Oncology (ESTRO), European Society of Pathology (ESP), European Society for Medical Oncology (ESMO), European Society of Radiology (ESR), European Society of Coloproctology (ESCP), European CanCer Organisation (ECCO), European Oncology Nursing Society (EONS) and the European Colorectal Cancer Patient Organisation (EuropaColon), as well as delegates from national registries or audits. Experts commented and voted on the two web-based online voting rounds before the meeting (between 4th and 25th October and between the 20th November and 3rd December 2012) as well as one online round after the meeting (4th-20th March 2013) and were invited to lecture on the subjects during the meeting (13th-15th December 2012). The sentences in the consensus document were available during the meeting and a televoting round during the conference by all participants was performed. All sentences that were voted on are available on the EURECCA website www.canceraudit.eu. The consensus document was divided in sections describing evidence based algorithms of diagnostics, pathology, surgery, medical oncology, radiotherapy, and follow-up where applicable for treatment of colon cancer, rectal cancer and stage IV separately. Consensus was achieved using the Delphi method. Results: The total number of the voted sentences was 465. All chapters were voted on by at least 75% of the experts. Of the 465 sentences, 84% achieved large consensus, 6% achieved moderate consensus, and 7% resulted in minimum consensus. Only 3% was disagreed by more than 50% of the members. Conclusions: It is feasible to achieve European Consensus on key diagnostic and treatment issues using the Delphi method. This consensus embodies the expertise of professionals from all disciplines involved in the care for patients with colon and rectal cancer. Diagnostic and treatment algorithms were developed to implement the current evidence and to define core treatment guidance for multidisciplinary team management of colon and rectal cancer throughout Europe.

Lampas y el espíritu de la naturaleza: estudio de la controversia entre Henry More y Robert Hooke

“Lampas y el Espíritu de la Naturaleza” estudia la controvèrsia entre Henry More i Robert Hooke a propòsit de la filosofia mecànica de la naturalesa en el context del pensament filosòfic i científic del segle XVII a Anglaterra, una controvèrsia que malgrat que es pugui considerar obsoleta en la seva forma no ho és en el seu fons, ja que tant les qüestions plantejades per More com les observacions de Hooke són pertinents i no són lluny, mutatis mutandis, de determinats plantejaments del nostre present.

Inversion Analytics: Análisis sobre rentabilidad de inversiones mediante VAN y TIR

Inversion Analytics es una herramienta para facilitar el análisis en inversiones que se planteen en pequeñas, medianas y grandes empresas, en el que se plasmará toda la información necesaria para determinar los valores que entran en juego en la inversión. La aplicación realiza esta función mediante el cálculo de VAN (Valor Actual Neto) y TIR (Tasa Interna de Rentabilidad) de una inversión determinada, a partir de la información introducida por el usuario y teniendo en cuenta los distintos métodos de amortización de la inversión inicial, así como los distintos enfoques o supuestos en el que clasificaremos el horizonte temporal de la misma.

La Inspiració de Van Gogh

La Inspiració de Van Gogh ofereix una reflexió entre les similituds i coincidències de dues societats (la societat de finals del sXIX, i la societat actual) separades pel temps, però unides per la necessitat de trobar una sortida a tanta incomprensió artística i social.

Response to the letter to the editor by Dr van den Berg

Letters to the editor

A cartography of the Van der Waals territory

The distribution of distances from atoms of a particular element E to a probe atom X (oxygen in most cases), both bonded and intermolecular non-bonded contacts, has been analyzed. In general, the distribution is characterized by a maximum at short EX distances corresponding to chemical bonds, followed by a range of unpopulated distances the van der Waals gap and a second maximum at longer distances the van der Waals peak superimposed on a random distribution function that roughly follows a d3 dependence. The analysis of more than five million interatomic"non-bonded" distances has led to the proposal of a consistent set of van der Waals radii for most naturally occurring elements, and its applicability to other element pairs has been tested for a set of more than three million data, all of them compared to over one million bond distances.

Els virus van fer evolucionar el cervell

Un retrovirus va contribuir a incrementar les capacitats cognitives dels éssers humans. Va incidir sobre un gen que també està involucrat en algunes malalties mentals

Cap a on van els programes de garantia social

En el present estudi es descriu l'experiència de la implantació dels PGS en la comunitat de Castella-La Manxa, partint d'un marc conceptual en el que es descriuen les modalitats i característiques de programes. Es detallen les dades obtingudes mitjançant d'un estudi empíric que ofereix informació sobre els diferents agents (professorat, alumnes, famílies) que concurreixen en tals Programes de Garantía Social.

Ellis-Van Creveld Syndrome. Case report and literature review

Ellis-van Creveld syndrome is a genetic disorder that was first described by Richard Ellis and Simon van Creveld in 1940. The four principal characteristics are chondrodysplasia, polydactyly, ectodermal dysplasia and congenital heart defects. The orofacial manifestations include multiple gingivolabial musculofibrous fraenula, dental anomalies, hypodontia and malocclusion. The disease can be diagnosed at any age, even during pregnancy. The differentiation should be made between Jeune syndrome and other orofaciodigital syndromes

Ellis-Van Creveld Syndrome. Case report and literature review

Ellis-van Creveld syndrome is a genetic disorder that was first described by Richard Ellis and Simon van Creveld in 1940. The four principal characteristics are chondrodysplasia, polydactyly, ectodermal dysplasia and congenital heart defects. The orofacial manifestations include multiple gingivolabial musculofibrous fraenula, dental anomalies, hypodontia and malocclusion. The disease can be diagnosed at any age, even during pregnancy. The differentiation should be made between Jeune syndrome and other orofaciodigital syndromes

New biogeographical and morphological information on Physaloptera ngoci Le-Van-Hoa, 1961 (Nematoda: Physalopteridae) in South-east Asian rodents

During a study of the helminth fauna of 1,643 rodents trapped along the Mekong River (Thailand, LaoPeople"s Democratic Republic and Cambodia) in 2008-2011, the spirurid nematode Physaloptera ngoci Le-Van-Hoa,1961 was recovered with an overall prevalence of 2.8%. Based on the original description, it was identified in nine of 23 different Murinae host species and is here reported for the first time from these three countries. A scanning electron microscopy study provides additional morphological data.

DOMINIQUE VALÉRIAN (ed.) (Cyrille Aillet, Sophie Gilotte, AnnelieseNef, Christophe Picard, Jean-Pierre Van Staëvel, Élise Voguet):Islamisation et arabisation de l’Occident musulman médiéval (VIIe–XIIesiècle)

This book is the result of a one-year seminar series"Islam médiéval d"Occident (VIIe-XVe)", held at the Colegio de España in Paris in 2006-07 by the Association des doctorants en histoire des mondes musulmans médievaux (Diwan http://diwan.hypotheses.org), and a second volume focusing on Arabization is expected (p. 33). The contributors" experience, alongside their university and research backgrounds, have led to the publication of articles of an outstandingly high level throughout this book. This scholarly achievement is combined with a thought-provoking theoretical framework, where Arabization and Islamization give a common theme to the proceedings, which are developed in four parts.

Actualidad de la Idea de una universidad de J. H. Newman

A mitjans de segle XIX, John Henry Newman va rebre l'encàrrec d'organitzar i dirigir una nova universitat a Dublin. Com a síntesi de les reflexions que van acompanyar aquell projecte, va publicar un escrit intitulat Idea of a University que encara avui dia ofereix nombrosos elements per a la reflexió de tots aquells que en formem part de la comunitat universitària. Els trets distintius de la universitat en què Newman hi pensa són: una vocació humil de servei que es concreta en la formació de persones, no tant de gentlemen o elits socials; primacia de l'educació de la intel·ligència especulativa, sense subordinar-la a l'educació moral ni a la formació tècnica; un lloc d'ensenyament del saber universal -deixant per altres institucions l'activitat de pura investigació- i de contacte viu entre les diferents especialitats -és bàsic l'intercanvi continu d'experiències entre docents i alumnes d'estudis diferents-; una acció tutorial que permeti descobrir en cada alumne els seus talents i les seves aptituds particulars; una producció o 'transferència de coneixement' vinculada a la vàlua real de l'activitat intel·lectual -qui publica ho fa perquè realment té quelcom a dir-. Com a rerefons d'aquestes propostes, Newman posa l'accent en la necessitat que la universitat sigui un ambient on es confia pregonament en la possibilitat d'accedir a un coneixement veritable de la realitat. Més que mai en un món intel·lectual que ja a mitjans segle XIX començava a trontollar sota el pes del nihilisme i l'escepticisme, Newman reivindica el valor de la veritat com a fi últim de tota vida universitària.