Genomic analysis of the blood attributed to Louis XVI (1754-1793), king of France.

A pyrographically decorated gourd, dated to the French Revolution period, has been alleged to contain a handkerchief dipped into the blood of the French king Louis XVI (1754-1793) after his beheading but recent analyses of living males from two Bourbon branches cast doubts on its authenticity. We sequenced the complete genome of the DNA contained in the gourd at low coverage (similar to 2.5x) with coding sequences enriched at a higher similar to 7.3x coverage. We found that the ancestry of the gourd's genome does not seem compatible with Louis XVI's known ancestry. From a functional perspective, we did not find an excess of alleles contributing to height despite being described as the tallest person in Court. In addition, the eye colour prediction supported brown eyes, while Louis XVI had blue eyes. This is the first draft genome generated from a person who lived in a recent historical period; however, our results suggest that this sample may not correspond to the alleged king.

Pasquale del Pezzo, Duke of Caianello, Neapolitan mathematician

This article is dedicated to a reconstruction of some events and achievements, both personal and scientific, in the life of the Neapolitan mathematician Pasquale del Pezzo, Duke of Caianello.

Median problems in networks

The P-median problem is a classical location model par excellence . In this paper we, firstexamine the early origins of the problem, formulated independently by Louis Hakimi andCharles ReVelle, two of the fathers of the burgeoning multidisciplinary field of researchknown today as Facility Location Theory and Modelling. We then examine some of thetraditional heuristic and exact methods developed to solve the problem. In the third sectionwe analyze the impact of the model in the field. We end the paper by proposing new lines ofresearch related to such a classical problem.

Els polítics de Lleida al Trienni Liberal (1820-1823)

En aquest estudi es pretén analitzar la composició social i ideològica dels quatre consistoris municipals que es van formar a la ciutat de Lleida al Trienni Liberal. A l'inici d'aquesta nova etapa històrica ja es va comprovar com els individus (sobretot nobles) que van controlar l'Ajuntament de Lleida al sexenni absolutista posterior a la Guerra del Francés van perdurar, per tant, no es produir cap revolució. Tot i que poc a poc aquests elements més absolutistes i com a màxim més identificats amb el liberalisme més moderat i proper al tradicionalisme van anant deixant pas a una nova classe dirigent política procedent dels sectors socials més dinàmics (professions liberals i activitats comercials), la qual va fer-se amb el consistori lleidatà a l'any 1823, va ser el triomf dels "exaltats". Aquesta experiència va finalitzar amb la invasió dels Cent Mil Fills de Sant Lluís i la posterior destrucció del règim constitucional.