Toward partial reorientation of land management for sustainability in view of material circulation: biophysical and historical analysis

This paper explores two major issues, from biophysical and historical viewpoints. We examine land management, which we define as the long-term fertility maintenance of land in relation to agriculture, fishery and forestry. We also explore humans’ positive role as agents aiming to reinforce harmonious materials circulation within the land. Liebig’s view on nature, agriculture and land, emphasizes the maintenance of long-term land fertility based on his agronomical thought that the circulation of matter in agricultural fields must be maintained with manure as much as possible. The thoughts of several classical economists, on nature, agriculture and land are reassessed from Liebig’s view point. Then, the land management problem is discussed at a much more fundamental level, to understand the necessary conditions for life in relation to land management. This point is analyzed in terms of two mechanisms: entropy disposal on the earth, and material circulation against gravitational field. Finally from the historical example of the metropolis of Edo, it is shown that there is yet another necessary condition for the sustainable management of land based on the creation of harmonious material cycles among cities, farm land, forests and surrounding sea areas in which humans play a vital role as agent.

Libertad contractual y pactos parasociales

L'objecte del present treball és doble. D'una banda tractem d'examinar la naturalesa dels pactes parasocials com una manifestació del principi de llibertat contractual i, per tant, de l'autonomia de la voluntat i, d'una altra, analitzar la conflictivitat que tals pactes estan provocant en relació amb el dret de societats. En tant que tals pactes, quan es perfeccionen entre tots els socis, constituïxen, junt amb els estatuts, el verdader contingut contractual de la societat, en especial quan es tracta de societats tancades, resulta un element d'incertesa que la seua operativitat quede en dubte com ocorre en la pràctica. Pensem en la importància que un pacte parasocial representa per a la protecció dels interessos de les minories i el sentiment de fracàs que es genera quan, pretenent aplicar allò que s'ha pactat per a preservar tals drets, no resulten operatius en tot allò que no haja resultat incorporat als estatuts socials, com a conseqüència de l'existència de dos categories d'obligacions contractuals: unes que, subjectes al dret de societats, representen uns drets i obligacions de categoria superior, que aquelles incloses en els pactes parasocials, que se subjecten al dret contractual. Per això, al final del treball, s'apunta la conveniència de, en la línia iniciada pel legislador quant a la regulació dels protocols familiars, normativitzar el tractament de tals pactes parasocials quan es tracte de defendre els drets de les minories socials. Finalment, la tendència legislativa de resoldre la problemàtica de la dicotomía, dret contractual versus dret societari, suscita una esperança amb el projecte de llei de modificació de la llei 60/2003 de arbitratge, en tramitació parlamentària en estos moments, on es contempla la possibilitat de sotmetre a arbitratge la impugnació d'acords socials.

Instituto de Seguridad Pública de Cataluña: integración activa del (E-) aprendizaje en el equipo técnico de la organización

El Instituto no contaba con campus virtual propio y la formación se impartía desde tres sedes electrónicas distintas, como se muestra en el gráfico adjunto, por lo cual en 2011 se decide montar entorno virtual de aprendizaje propio y asumir con agentes internos (personal técnico del ISPC y miembros de los cuerpos de policías y bomberos) el diseño y elaboración de las propuestas formativas. En el documento se explica los pasos seguidos hasta llegar al entorno virtual.

Anàlisi del Cicle de Vida (ACV) del Monoestearat de Glicerina a CRODA Ibérica, S.A. – Mevisa Site

L’estudi de l’Anàlisi del Cicle de Vida (ACV) ha estat realitzat a l’empresa CRODA Ibèrica S.A - Mevisa Site, en concret a la línia productiva on s’hi fabrica el monoestearat de glicerina utilitzant una eina informàtica comercial denominada SIMAPRO que analitza i compara els aspectes mediambientals d’un producte d’una manera sistemàtica i consistent seguint les recomanacions de les normes ISO 14040

Avaluació, seguiment i propostes de millora de les actuacions de recuperació del Massís del Montgrí després de l’incendi del 2004

El treball pretén donar unes pautes generals de com actuar en una zona cremada després d’un incendi, tant pel que es refereix als treballs d’urgència, com el que fa referència als treballs destinats a la restauració, concretament, estudia el cas de l’incendi que va patir el massís del Montgrí el setembre de 2004, tenint en compte que aquesta zona forma part dels espais PEIN de Catalunya, es troba proposada com a zona ZEPA per la Xarxa Natura 2000 i es preveu la seva integració en un nou Parc Natural

Evaluación de competencias a través de la resolución de casos clínicos integrados. Posters y comunicaciones del IV Encuentro de Profesorado de Ciencias de la Salud y XI Jornadas de Docencia de Medicina.

Introducción: La E.U.Enfermería Gimbernat participa en el Plan Piloto del Departamento de Universidades de la Generalitat de Catalunya para la adaptación de la titulación de Enfermería a los criterios de la Convergencia Europea. En el actual curso 2006-2007, la adaptación incluye todas las asignaturas de 1er y 2º curso, y es en este último donde se ubica...

Polymorphisms in DNA-repair genes in a cohort of prostate cancer patients from different areas in Spain: heterogeneity between populations as a confounding factor in association studies

Background: Differences in the distribution of genotypes between individuals of the same ethnicity are an important confounder factor commonly undervalued in typical association studies conducted in radiogenomics. Objective: To evaluate the genotypic distribution of SNPs in a wide set of Spanish prostate cancer patients for determine the homogeneity of the population and to disclose potential bias. Design, Setting, and Participants: A total of 601 prostate cancer patients from Andalusia, Basque Country, Canary and Catalonia were genotyped for 10 SNPs located in 6 different genes associated to DNA repair: XRCC1 (rs25487, rs25489, rs1799782), ERCC2 (rs13181), ERCC1 (rs11615), LIG4 (rs1805388, rs1805386), ATM (rs17503908, rs1800057) and P53 (rs1042522). The SNP genotyping was made in a Biotrove OpenArrayH NT Cycler. Outcome Measurements and Statistical Analysis: Comparisons of genotypic and allelic frequencies among populations, as well as haplotype analyses were determined using the web-based environment SNPator. Principal component analysis was made using the SnpMatrix and XSnpMatrix classes and methods implemented as an R package. Non-supervised hierarchical cluster of SNP was made using MultiExperiment Viewer. Results and Limitations: We observed that genotype distribution of 4 out 10 SNPs was statistically different among the studied populations, showing the greatest differences between Andalusia and Catalonia. These observations were confirmed in cluster analysis, principal component analysis and in the differential distribution of haplotypes among the populations. Because tumor characteristics have not been taken into account, it is possible that some polymorphisms may influence tumor characteristics in the same way that it may pose a risk factor for other disease characteristics. Conclusion: Differences in distribution of genotypes within different populations of the same ethnicity could be an important confounding factor responsible for the lack of validation of SNPs associated with radiation-induced toxicity, especially when extensive meta-analysis with subjects from different countries are carried out.

Comparison of quality of life after stereotactic body radiotherapy and surgery for early-stage prostate cancer

Background: As the long-term efficacy of stereotactic body radiation therapy (SBRT) becomes established and other prostate cancer treatment approaches are refined and improved, examination of quality of life (QOL) following prostate cancer treatment is critical in driving both patient and clinical treatment decisions. We present the first study to compare QOL after SBRT and radical prostatectomy, with QOL assessed at approximately the same times pre- and post-treatment and using the same validated QOL instrument. Methods: Patients with clinically localized prostate cancer were treated with either radical prostatectomy (n = 123 Spanish patients) or SBRT (n = 216 American patients). QOL was assessed using the Expanded Prostate Cancer Index Composite (EPIC) grouped into urinary, sexual, and bowel domains. For comparison purposes, SBRT EPIC data at baseline, 3 weeks, 5, 11, 24, and 36 months were compared to surgery data at baseline, 1, 6, 12, 24,and 36 months. Differences in patient characteristics between the two groups were assessed using Chi-squared tests for categorical variables and t-tests for continuous variables. Generalized estimating equation (GEE) models were constructed for each EPIC scale to account for correlation among repeated measures and used to assess the effect of treatment on QOL. Results: The largest differences in QOL occurred in the first 16 months after treatment, with larger declines following surgery in urinary and sexual QOL as compared to SBRT, and a larger decline in bowel QOL following SBRT as compared to surgery. Long-term urinary and sexual QOL declines remained clinically significantly lower for surgery patients but not for SBRT patients. Conclusions: Overall, these results may have implications for patient and physician clinical decision making which are often influenced by QOL. These differences in sexual, urinary and bowel QOL should be closely considered in selecting the right treatment, especially in evaluating the value of non-invasive treatments, such as SBRT.

The reappearance of a forgotten disease in the oral cavity: syphilis

Syphilis is a sexually transmitted disease (STD) produced by Treponema pallidum, which mainly affects humans and is able to invade practically any organ in the body. Its infection facilitates the transmission of other STDs. Since the end of the last decade, successive outbreaks of syphilis have been reported in most western European countries. Like other STDs, syphilis is a notifiable disease in the European Union. In Spain, epidemiological information is obtained nationwide via the country"s system for recording notifiable diseases (Spanish acronym EDO) and the national microbiological information system (Spanish acronym SIM), which compiles information from a network of 46 sentinel laboratories in twelve Spanish regions. The STDs that are epidemiologically controlled are gonococcal infection, syphilis, and congenital syphilis. The incidence of each of these diseases is recorded weekly. The information compiled indicates an increase in the cases of syphilis and gonococcal infection in Spain in recent years. According to the EDO, in 1999, the number of cases of syphilis per 100,000 inhabitants was recorded to be 1.69, which has risen to 4.38 in 2007. In this article, we review the reappearance and the evolution of this infectious disease in eight European countries, and alert dentists to the importance of a) diagnosing sexuallytransmitted diseases and b) notifying the centres that control them

Comparison of quality of life after stereotactic body radiotherapy and surgery for early-stage prostate cancer

Background: As the long-term efficacy of stereotactic body radiation therapy (SBRT) becomes established and other prostate cancer treatment approaches are refined and improved, examination of quality of life (QOL) following prostate cancer treatment is critical in driving both patient and clinical treatment decisions. We present the first study to compare QOL after SBRT and radical prostatectomy, with QOL assessed at approximately the same times pre- and post-treatment and using the same validated QOL instrument. Methods: Patients with clinically localized prostate cancer were treated with either radical prostatectomy (n = 123 Spanish patients) or SBRT (n = 216 American patients). QOL was assessed using the Expanded Prostate Cancer Index Composite (EPIC) grouped into urinary, sexual, and bowel domains. For comparison purposes, SBRT EPIC data at baseline, 3 weeks, 5, 11, 24, and 36 months were compared to surgery data at baseline, 1, 6, 12, 24,and 36 months. Differences in patient characteristics between the two groups were assessed using Chi-squared tests for categorical variables and t-tests for continuous variables. Generalized estimating equation (GEE) models were constructed for each EPIC scale to account for correlation among repeated measures and used to assess the effect of treatment on QOL. Results: The largest differences in QOL occurred in the first 1-6 months after treatment, with larger declines following surgery in urinary and sexual QOL as compared to SBRT, and a larger decline in bowel QOL following SBRT as compared to surgery. Long-term urinary and sexual QOL declines remained clinically significantly lower for surgery patients but not for SBRT patients. Conclusions: Overall, these results may have implications for patient and physician clinical decision making which are often influenced by QOL. These differences in sexual, urinary and bowel QOL should be closely considered in selecting the right treatment, especially in evaluating the value of non-invasive treatments, such as SBRT.

La reaparición de una olvidada enfermedad en la cavidad oral: la sífilis

La sífilis es una enfermedad de transmisión sexual (ETS) producida por el Treponema pallidum, que infecta principalmente a seres humanos y que es capaz de invadir casi cualquier órgano del cuerpo. Su infección facilita la transmisión de otras ETS. Desde finales de la última década hasta la actualidad, han ido apareciendo sucesivos brotes de sífilis en la mayor parte de países de la Europa Occidental. La sífilis, junto con otras ETS, es una enfermedad de declaración obligatoria en los países de la Unión Europea. Concretamente en España, la infonnación epidemiológica a nivel estatal se obtiene a través del Sistema de Enfemledades de Declaración Obligatoria (EDO) y del Sistema de Información Microbiológica (SIM), que recopila infonnación de una red de 46 laboratorios centinela situados en 12 Comunidades Autónomas. Las ETS sometidas a vigilancia epidemiológica son la infección gonocócica, la sífilis y la sífilis congénita, todas ellas de declaración numérica semanal. Con esta información se ha podido apreciar en los últimos años un incremento en los casos de sífilis y gonococia notificados en España (las tasas de sífilis por 100.000 habitantes en el año 1999 fueron de 1,69 y en el 2007 de 4,38 notificadas al sistema EDO). En este artículo revisamos el resurgimiento y la evolución de esta enfermedad infecciosa en ocho países europeos, a la vez que pretendemos llamar la atención a los dentistas acerca del papel que deben desempeñar en el diagnóstico de la enfennedad y en la derivación a centros de control de infecciones de transmisión sexual

Localized prostate cancer in Norway, the United States, and Spain: between-country differences of variables before treatment among patients eligible for curative treatment

Between-country differences in medical and sociodemographic variables, and patient-related outcomes (PROs) before treatment might explain published variations of side effects after radical prostatecomy (RP) or radiotherapy (RAD) for prostate cancer (PCa). This hypothesis was tested among 1908 patients from the United States, Spain, and Norway. Significant between-country differences were observed for most factors investigated before treatment. The observations should be considered in comparison of the frequency and severity of internationally published studies. Background: In men with PCa, large variations of PROs after RP or high-dose RAD might be related to betweencountry differences of medical and sociodemographic variables, and differences in PROs before treatment in the sexual and urinary domains. Patients and Methods: In 1908 patients with localized PCa from Norway, the United States, or Spain, the relation between medical (prostate-specific antigen, Gleason score, cT-category) and sociodemographic variables (age, education, marital status) before treatment was investigated. Using the Expanded Prostate Cancer Index Composite questionnaire, PROs before treatment within the sexual and urinary domains were also considered. Results: Compared with the European patients, American patients were younger, fewer had comorbid conditions, and more had a high education level. Fifty-three percent of the US men eligible for RP had low-risk tumors compared with 42% and 31% among the Norwegian and the Spanish patients, respectively. Among the Spanish RAD patients, 54% had had low-risk tumors compared with 34% of the American and 21% of the Norwegian men planned for RAD, respectively. Compared with the European patients, significantly fewer US patients reported moderate or severe sexual dysfunction and related problems. In most subgroups, the number of patients with sexual or urinary dysfunction exceeded that of patients with bother related to the reported dysfunction. Conclusion: Statistically significant between-country differences were observed in medical and sociodemographic variables, and in PROs before treatment within the sexual and urinary domains. Large differences between reported dysfunction and related problems within the sexual and urinary domains indicate that dysfunction and bother should be reported separately in addition to calculation of summary scores. The documented differences, not at least regarding PROs, might in part explain the large variation of side effects after treatment evident in the medical literature

Polymorphisms in DNA-repair genes in a cohort of prostate cancer patients from different areas in Spain: heterogeneity between populations as a confounding factor in association studies

Background: Differences in the distribution of genotypes between individuals of the same ethnicity are an important confounder factor commonly undervalued in typical association studies conducted in radiogenomics. Objective: To evaluate the genotypic distribution of SNPs in a wide set of Spanish prostate cancer patients for determine the homogeneity of the population and to disclose potential bias. Design, Setting, and Participants: A total of 601 prostate cancer patients from Andalusia, Basque Country, Canary and Catalonia were genotyped for 10 SNPs located in 6 different genes associated to DNA repair: XRCC1 (rs25487, rs25489, rs1799782), ERCC2 (rs13181), ERCC1 (rs11615), LIG4 (rs1805388, rs1805386), ATM (rs17503908, rs1800057) and P53 (rs1042522). The SNP genotyping was made in a Biotrove OpenArrayH NT Cycler. Outcome Measurements and Statistical Analysis: Comparisons of genotypic and allelic frequencies among populations, as well as haplotype analyses were determined using the web-based environment SNPator. Principal component analysis was made using the SnpMatrix and XSnpMatrix classes and methods implemented as an R package. Non-supervised hierarchical cluster of SNP was made using MultiExperiment Viewer. Results and Limitations: We observed that genotype distribution of 4 out 10 SNPs was statistically different among the studied populations, showing the greatest differences between Andalusia and Catalonia. These observations were confirmed in cluster analysis, principal component analysis and in the differential distribution of haplotypes among the populations. Because tumor characteristics have not been taken into account, it is possible that some polymorphisms may influence tumor characteristics in the same way that it may pose a risk factor for other disease characteristics. Conclusion: Differences in distribution of genotypes within different populations of the same ethnicity could be an important confounding factor responsible for the lack of validation of SNPs associated with radiation-induced toxicity, especially when extensive meta-analysis with subjects from different countries are carried out.

Estudio del yeísmo en el español de Barcelona a partir de materiales de PRESEEA

En enero de 2006, el equipo de investigación sociolingüística de la Universidad deBarcelona, integrado por profesores y doctorandos del Departamento de FilologíaHispánica, se incorporó al Proyecto para el Estudio Sociolingüístico del Español deEspaña y de América (PRESEEA), vinculado a la Asociación de Lingüística y Filologíade América Latina (ALFAL), y que tiene como coordinador general a FranciscoMoreno Fernández, Catedrático de Lengua Española de la Universidad de Alcalá. Dichoproyecto se organiza en una red internacional de equipos de investigación cuyo objetivocentral es el de reunir un ingente corpus oral, sociolingüísticamente representativo, deun gran número de ciudades pertenecientes al mundo hispánico. La primera fase delproyecto, que se presentó en 1996, abarca hasta el año 2010 (Moreno Fernández 2006).1Para el estudio de Barcelona, en el seno del grupo PRESEEA – BARCELONA – ESdiseñamos una plantilla que contempla una representación de 108 informantes (loscuales deben haber nacido en la ciudad, haber llegado a ella antes de cumplir los diezaños o llevar viviendo en el lugar más de veinte), distribuidos en tres variables depreestratificación: sexo, edad y nivel de instrucción. A este perfil general añadimos lavariable ‘lengua primera’ (catalán / español), vista la repercusión que alcanza laconvivencia de las dos lenguas en la ciudad (Torres 2007).En las páginas que siguen, nos proponemos abordar el avance real del yeísmo en laCiudad Condal a partir de unas muestras seleccionadas de los datos de PRESEEABARCELONA-ES. El trabajo, que básicamente es de carácter fonético y presenta unanálisis acústico centrado en aspectos frecuenciales, de duración y de intensidad de lasmuestras mencionadas, pretende ser un primer acercamiento al estadio en el que se encuentra el fenómeno en esta área específica.

Estudio del yeísmo en el español de Barcelona a partir de materiales de PRESEEA

En enero de 2006, el equipo de investigación sociolingüística de la Universidad deBarcelona, integrado por profesores y doctorandos del Departamento de FilologíaHispánica, se incorporó al Proyecto para el Estudio Sociolingüístico del Español deEspaña y de América (PRESEEA), vinculado a la Asociación de Lingüística y Filologíade América Latina (ALFAL), y que tiene como coordinador general a FranciscoMoreno Fernández, Catedrático de Lengua Española de la Universidad de Alcalá. Dichoproyecto se organiza en una red internacional de equipos de investigación cuyo objetivocentral es el de reunir un ingente corpus oral, sociolingüísticamente representativo, deun gran número de ciudades pertenecientes al mundo hispánico. La primera fase delproyecto, que se presentó en 1996, abarca hasta el año 2010 (Moreno Fernández 2006).1Para el estudio de Barcelona, en el seno del grupo PRESEEA – BARCELONA – ESdiseñamos una plantilla que contempla una representación de 108 informantes (loscuales deben haber nacido en la ciudad, haber llegado a ella antes de cumplir los diezaños o llevar viviendo en el lugar más de veinte), distribuidos en tres variables depreestratificación: sexo, edad y nivel de instrucción. A este perfil general añadimos lavariable ‘lengua primera’ (catalán / español), vista la repercusión que alcanza laconvivencia de las dos lenguas en la ciudad (Torres 2007).En las páginas que siguen, nos proponemos abordar el avance real del yeísmo en laCiudad Condal a partir de unas muestras seleccionadas de los datos de PRESEEABARCELONA-ES. El trabajo, que básicamente es de carácter fonético y presenta unanálisis acústico centrado en aspectos frecuenciales, de duración y de intensidad de lasmuestras mencionadas, pretende ser un primer acercamiento al estadio en el que se encuentra el fenómeno en esta área específica.