97 resultados para Patent citation
Resumo:
Patent ductus arteriosus is a prevalent problem in low birth weight infants and it has an important morbidity and mortality in this group of patients. Classical treatment options include drugs (intravenous cyclooxygenase inhibitors: indomethacin and ibuprofen) and surgical ligation, but these treatments are associated with significant adverse effects. An alternative treatment with fewer side effects is needed. The role of oral paracetamol has gained importance in recent years, this new therapeutic option is being widely studied, and there are already many studies which support oral paracetamol as first line treatment for PDA, due to its better safety profile than classical drugs. In LBW infants is difficult to administer enteral treatment, since they are often multi pathological patients with several complications that preclude oral administration and they usually receive intravenous treatments. This multicenter, prospective, single blinded, randomized, controlled, parallel-group and noninferiority trial is designed to evaluate the efficacy and safety of intravenous paracetamol versus intravenous ibuprofen in the treatment of PDA in LBW infants. Sixty eight infants with echocardiography confirmed PDA will be randomly assigned to receive either intravenous paracetamol or intravenous ibuprofen. The main endpoints will be the rate of ductal closure of each drug and adverse events in each group of treatment
Resumo:
Quan l’any 1602 el pintor i tractadista Federico Zuccari publicà L’Ideade’pittori, scultori et architetti, Caravaggio ja havia radicalitzat el seu llenguatge versun fort naturalisme, al qual afegia un tractament de forts contrastos lumínics patent enl’obra, dos anys més tardana, que inaugura la mostra: La verge de Loreto, tambéconeguda com la Verge del peregrins. Davant el procés creatiu de Zuccari basat en laIdea, es a dir el disegno interno de bellesa, Caravaggio pren la realitat com a modeltrencant així amb el manierisme reformat que, a la Roma papal, te la seva plasmació al’Oratori dels Gonfalone on el citat tractadista hi va participar. D’altra banda la novamanera caravaggesca es contraria a la proposada per Annibale Carracci al programa dela Galeria Farnese i, alhora, per la defensada per tota la tractadística italiana del segleXVII, des de Giovanni Battista Agucchi, en el seu Tractat de la pintura(1607-1615),fins a Giovan Pietro Bellori en el seu discurs L’Idea del pittore, dello scultore edell’architetto, scelta dalle bellezze naturali superiore alla natura que seguint els vellsprincipis de la Poètica defensen que l’obra d’art ha de tenir versemblança, ha d’imitar els millors i pot corregir la realitat. No es estrany, doncs, que Agucchi posi comexemple a seguir l’art d’Annibale Carracci i que compari a Caravaggio amb l’escultorgrec Demetri, que va seguir tant al peu de la lletra la semblança que no va tenirconsideració per la bellesa.
Resumo:
Research on limnology in southern Europe had achieved a notable presence in the international arena before the onset of the current dramatic cuts in public investment in science. We assessed the limnological research published in peer-reviewed journals by Spanish and Portuguese (i.e., Iberian) researchers during the decade prior to the economic recession (2000 to 2009). The Thompson Reuters Web of Knowledge database was used to retrieve all publications on limnology authored by researchers affiliated with Spanish or Portuguese institutions independently of the geographical setting of the study. The publishing pattern was characterised in terms of authors, journals, and citation statistics. In addition, a thematic characterisation of the research was performed by a manual assignation of several categorical descriptors combined with a blind word count analysis. Iberian researchers produced an annual mean of 278 papers on limnology. Papers were published in journals that had impact factors ranging from 0.1 to 31.4, with a mean of 2.0. Based on citations, the impact of the Iberian limnological research was not due to a few highly cited papers but rather to a wide number of publications; each paper received a mean of 8 citations. The Iberian limnological research involved up to 5460 researchers, with a mean of 4.3 authors per paper. The research largely focused on fluvial systems, with 47 % of total publications (2778) devoted to these ecosystems. There was a dominant focus on local, within-system aspects of study sites and the research was mostly restricted to the Iberian Peninsula; larger spatial scales of analysis (i.e., landscape, regional, or global) tended to be overlooked. Iberian research addressed fundamental (75 %) rather than applied (17 %) or methodological (5 %) questions and was vastly dominated by observational approaches (75 %). Interestingly, Iberian limnological research increased its scientific productivity during the analysed decade at a higher rate than its international counterpart (increase of 119 %). Overall, Iberian research on limnology appeared to be in good health during the analysed decade. Certain areas have been more studied than others, which opens opportunities to develop new research.
Resumo:
Tradicionalment, bona part dels científics que treballem en institucions públiques hem pensat que la manera més eficient per avançar en ciència és permetre el lliure accés al coneixement, una idea que aquestes mateixes institucions tendeixen a fer canviar estimulant-nos a patentar les nostres troballes -i si cal també ens ajuden a crear un spin-off per rendibilitzar-les econòmicament- [...].
Resumo:
The fusion of knowledge, the interrelationship of disciplines and, finally, the interaction of learning fields, provides new challenges for an auto denominated global society. The contemporary value of landscape, linked to the patent commodification of culture, the commercial construction of identities, the triumph of inauthenticity, of the induced representation or the economy of symbolism, open up great prospects for studying the symbolic value of landscape. The rapprochement of geographical praxis to the study of space intangibles, linked to the discovery of emotional geographies, besides the growing interest of communicational sciences on the territorial discourse, allow us to envisage a communicative study of landscape based on a fusion of geographical and communicational knowledge. The balancing of the variables: geography, landscape, emotion and communication, enables the progress towards analysing the emotionalisation of space to discern its intangible value, which emerges from the application of different communication techniques.
Resumo:
Aquest informe recull els 228 treballs publicats per 177 investigadors/es del Campus de Terrassa en revistes indexades al Journal Citation Report durant el 2013