70 resultados para Emerging technologies
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Peer-reviewed
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Peer-reviewed
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Peer-reviewed
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Emerging human rights are destined to modify, improve and transform a number of already traditional concepts so as to achieve greater guarantees and protection for the rights of individuals and collectivities. One of the big changes that will be brought about by the concept and conception of emerging human rights is that, following on from the processes of positivization, generalization, internationalization and specification, they represent the beginning of the fifth historical process in the consolidation of human rights, namely the process of interaction. A number of breakthroughs have already been achieved, such as the recognition of emerging biocultural rights in the recently adopted Nagoya Protocol on access to genetic resources and shared benefits.
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Background: Since the use of pneumococcal conjugate vaccines PCV7 and PCV13 in children became widespread, invasive pneumococcal disease (IPD) has dramatically decreased. Nevertheless, there has been a rise in incidence of Streptococcus pneumoniae non-vaccine serotypes (NVT) colonising the human nasopharynx. Nasopharyngeal colonisation, an essential step in the development of S. pneumoniae-induced IPD, is associated with biofilm formation. Although the capsule is the main pneumococcal virulence factor, the formation of pneumococcal biofilms might, in fact, be limited by the presence of capsular polysaccharide (CPS). Methodology/Principal Findings: We used clinical isolates of 16 emerging, non-PCV13 serotypes as well as isogenic transformants of the same serotypes. The biofilm formation capacity of isogenic transformants expressing CPSs from NVT was evaluated in vitro to ascertain whether this trait can be used to predict the emergence of NVT. Fourteen out of 16 NVT analysed were not good biofilm formers, presumably because of the presence of CPS. In contrast, serotypes 11A and 35B formed >45% of the biofilm produced by the non-encapsulated M11 strain. Conclusions/Significance This study suggest that emerging, NVT serotypes 11A and 35B deserve a close surveillance.
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Sobre el impacto que las TIC pueden tener en las relaciones interpersonales, ya sean en la familia y/o con los amigos/as, desde una perspectiva psicosocial
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A lo largo de la última década, la adolescencia ha sido un tema dediscusión política en distintos espacios europeos al más alto nivel. En unasociedad aceleradamente cambiante se percibe que la adecuada socializaciónde las generaciones más jóvenes constituye un reto socio-históricoque nos afecta a todos. Los cambios en que estamos sumergidos son tanplurales (demográficos, sociales, tecnológicos, económicos, políticos,etc.) que generan un amplísimo frente de nuevos dilemas éticos. La opiniónde los ciudadanos de la Unión Europea se muestra preocupada pornuevos valores y destaca la preferencia por la responsabilidad en coherenciacon dicha situación cambiante. Todo este macrocontexto psicosocialviene planteando nuevos retos teóricos y de investigación a la comunidadcientífica. De hecho las ciencias humanas y sociales han empezadoa desarrollar nuevas líneas de investigación para comprender mejor lasnuevas relaciones entre adultos y adolescentes y las nuevas culturas queemergen entre estos últimos, impulsadas por nuevas aspiraciones socialescompartidas por grupos más o menos amplios de la población joven. Eldesarrollo de técnicas e instrumentos que nos permitan comprender mejorla perspectiva del adolescente se hace más evidente si analizamos su relacióncon las nuevas tecnologías de la información y la comunicación. Dichastecnologías comportan nuevos riesgos, pero también nuevas oportunidades,entre las que destaca la posibilidad de establecer nuevas formasde relación. La motivación que muestran los más jóvenes por las nuevastecnologías constituye un gran reto a los investigadores aplicados parasugerir formas de maximizar las potencialidades latentes
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The high sensitivity and excellent timing accuracy of Geiger mode avalanche photodiodes makes them ideal sensors as pixel detectors for particle tracking in high energy physics experiments to be performed in future linear colliders. Nevertheless, it is well known that these sensors suffer from dark counts and afterpulsing noise, which induce false hits (indistinguishable from event detection) as well as an increase of the necessary area of the readout system. In this work, we present a comparison between APDs fabricated in a high voltage 0.35 µm and a high integration 0.13 µm commercially available CMOS technologies that has been performed to determine which of them best fits the particle collider requirements. In addition, a readout circuit that allows low noise operation is introduced. Experimental characterization of the proposed pixel is also presented in this work.
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Avalanche photodiodes operated in the Geiger mode present very high intrinsic gain and fast time response, which make the sensor an ideal option for those applications in which detectors with high sensitivity and velocity are required. Moreover, they are compatible with conventional CMOS technologies, allowing sensor and front-end electronics integration within the pixel cell. Despite these excellent qualities, the photodiode suffers from high intrinsic noise, which degrades the performance of the detector and increases the memory area to store the total amount of information generated. In this work, a new front-end circuit that allows low reverse bias overvoltage sensor operation to reduce the noise in Geiger mode avalanche photodiode pixel detectors is presented. The proposed front-end circuit also enables to operate the sensor in the gated acquisition mode to further reduce the noise. Experimental characterization of the fabricated pixel with the conventional HV-AMS 0.35µm technology is also presented in this article.