Generalized Multiobjective Multitree model solution using MOEA

In a previous paper a novel Generalized Multiobjective Multitree model (GMM-model) was proposed. This model considers for the first time multitree-multicast load balancing with splitting in a multiobjective context, whose mathematical solution is a whole Pareto optimal set that can include several results than it has been possible to find in the publications surveyed. To solve the GMM-model, in this paper a multi-objective evolutionary algorithm (MOEA) inspired by the Strength Pareto Evolutionary Algorithm (SPEA) is proposed. Experimental results considering up to 11 different objectives are presented for the well-known NSF network, with two simultaneous data flows

El sistema de gestión documental de la Universitat de Barcelona en el marco de la Administración electrónica: un elemento más para fomentar la mejora continua

[eng] We describe the project for the organization of the documentary management system at the University of Barcelona, which is inspired by the opportunities presented by the introduction of electronic administration. We stress the function of the documentary management system as an agent for promoting continuous innovation and improvement. We illustrate this vision with a description of the process of introducing the documentary management system in the area of research.

El sistema de gestió documental de la Universitat de Barcelona en el marc de l'Administració electrònica: un element més per fomentar la millora contínua

[eng] We describe the project for the organization of the documentary management system at the University of Barcelona, which is inspired by the opportunities presented by the introduction of electronic administration. We stress the function of the documentary management system as an agent for promoting continuous innovation and improvement. We illustrate this vision with a description of the process of introducing the documentary management system in the area of research.

Trade policy and regional inequalities

This paper aims to analyse the effects of trade policies in the pattern of regional inequalities within a country. Inspired firstly, by the debate concerning the role of protectionist policies in the settlement of a pattern of striking regional inequalities in the Spanish industrialisation process and secondly, by current evidence of an increase in these inequalities following the entry of Spain in the EU (1986), we set a model that shows that trade liberalisation increases regional inequalities.

Constraints on additional Z' gauge bosons from a precise measurement of the Z mass

We analyze the constraints on the mass and mixing of a superstring-inspired E6 Z' neutral gauge boson that follow from the recent precise Z mass measurements and show that they depend very sensitively on the assumed value of the W mass and also, to a lesser extent, on the top-quark mass.

Exported oscillator competition: A concept to analyse complex rhytms

We study the interaction between two independent nonlinear oscillators competing through a neutral excitable element. The first oscillator, completely deterministic, acts as a normal pacemaker sending pulses to the neutral element which fires when it is excited by these pulses. The second oscillator, endowed with some randomness, though unable to make the excitable element to beat, leads to the occasional suppression of its firing. The missing beats or errors are registered and their statistics analyzed in terms of the noise intensity and the periods of both oscillators. This study is inspired in some complex rhythms such as a particular class of heart arrhythmia.

Cal.limac h. VI, Euforió fr. 8 Powell i les "tauletes de maledicció" de Cnidos

The scene from Callirnachus' H. VI in which Derneter, under the appearance of her arateira Nicippa, curses Erisichthon rnay be related to the arai of Cnidos. On the other hand, Euphorio fr. 8 Powell can be understood better in the light of the curses of Cnidos, where the culprit's name is not rnentioned ut rhe first stage; a similar interpretation can be applied to Ovid's Ibis 7-10, which was probably inspired on Euphorio

Conserved chromosomal clustering of genes governed by chromatin regulators in Drosophila

Background: The trithorax group (trxG) and Polycomb group (PcG) proteins are responsible for the maintenance of stable transcriptional patterns of many developmental regulators. They bind to specific regions of DNA and direct the post-translational modifications of histones, playing a role in the dynamics of chromatin structure.Results: We have performed genome-wide expression studies of trx and ash2 mutants in Drosophila melanogaster. Using computational analysis of our microarray data, we have identified 25 clusters of genes potentially regulated by TRX. Most of these clusters consist of genes that encode structural proteins involved in cuticle formation. This organization appears to be a distinctive feature of the regulatory networks of TRX and other chromatin regulators, since we have observed the same arrangement in clusters after experiments performed with ASH2, as well as in experiments performed by others with NURF, dMyc, and ASH1. We have also found many of these clusters to be significantly conserved in D. simulans, D. yakuba, D. pseudoobscura and partially in Anopheles gambiae.Conclusion: The analysis of genes governed by chromatin regulators has led to the identification of clusters of functionally related genes conserved in other insect species, suggesting this chromosomal organization is biologically important. Moreover, our results indicate that TRX and other chromatin regulators may act globally on chromatin domains that contain transcriptionally co-regulated genes.

De llibertat, autoritat i in/dependències (a la vida i l'obra de Maria-Mercè Marçal)

This article pays attention to two moments in the life and work (inseparably united) of Maria-Mercè Marçal. The first refers to a search of small objects presided by the moon. Taking this search as a motif, the freedom which the poet confers to the nocturnal light ¿mythical and magical symbol of femaleness- and, therefore, to that which symbolises the heavenly body, is revealed. The second moment revolves around the reflection of Marçal on the ¿female authority¿, a concept which this author, inspired by the philosophical community of Diotima, distinguishes from power. Throughout history, Maria-Mercè Marçal remarked, many women have gained strength from the free atribution of authority to other women, to their texts, to their experiences.

Synthetic applications of chiral unsaturated epoxy alcohols prepared by sharpless asymmetric epoxidation

An overview of the synthesis and applications of chiral 2,3-epoxy alcohols containing unsaturated chains is presented. One of the fundamental synthetic routes to these compounds is Sharpless asymmetric epoxidation, which is reliable, highly chemoselective and enables easy prediction of the product enantioselectivity. Thus, unsaturated epoxy alcohols are readily obtained by selective oxidation of the allylic double bond in the presence of other carbon-carbon double or triple bonds. The wide availability of epoxy alcohols with unsaturated chains, the versatility of the epoxy alcohol functionality (e.g. regio- and stereo-selective ring opening; oxidation; and reduction), and the arsenal of established alkene chemistries, make unsaturated epoxy alcohols powerful starting materials for the synthesis of complex targets such as biologically active molecules. The popularization of ring-closing metathesis has further increased their value, making them excellent precursors to cyclic compounds.

Trade policy and regional inequalities

This paper aims to analyse the effects of trade policies in the pattern of regional inequalities within a country. Inspired firstly, by the debate concerning the role of protectionist policies in the settlement of a pattern of striking regional inequalities in the Spanish industrialisation process and secondly, by current evidence of an increase in these inequalities following the entry of Spain in the EU (1986), we set a model that shows that trade liberalisation increases regional inequalities.

Modeling storm events to investigate the influence of the stream¿catchment interface zone on stream biogeochemistry

We formulate a new mixing model to explore hydrological and chemical conditions under which the interface between the stream and catchment interface (SCI) influences the release of reactive solutes into stream water during storms. Physically, the SCI corresponds to the hyporheic/riparian sediments. In the new model this interface is coupled through a bidirectional water exchange to the conventional two components mixing model. Simulations show that the influence of the SCI on stream solute dynamics during storms is detectable when the runoff event is dominated by the infiltrated groundwater component that flows through the SCI before entering the stream and when the flux of solutes released from SCI sediments is similar to, or higher than, the solute flux carried by the groundwater. Dissolved organic carbon (DOC) and nitrate data from two small Mediterranean streams obtained during storms are compared to results from simulations using the new model to discern the circumstances under which the SCI is likely to control the dynamics of reactive solutes in streams. The simulations and the comparisons with empirical data suggest that the new mixing model may be especially appropriate for streams in which the periodic, or persistent, abrupt changes in the level of riparian groundwater exert hydrologic control on flux of biologically reactive fluxes between the riparian/hyporheic compartment and the stream water.

Coisotropic regularization of singular Lagrangians

We present an alternative approach to the usual treatments of singular Lagrangians. It is based on a Hamiltonian regularization scheme inspired on the coisotropic embedding of presymplectic systems. A Lagrangian regularization of a singular Lagrangian is a regular Lagrangian defined on an extended velocity phase space that reproduces the original theory when restricted to the initial configuration space. A Lagrangian regularization does not always exists, but a family of singular Lagrangians is studied for which such a regularization can be described explicitly. These regularizations turn out to be essentially unique and provide an alternative setting to quantize the corresponding physical systems. These ideas can be applied both in classical mechanics and field theories. Several examples are discussed in detail. 1995 American Institute of Physics.

Cognate peptide-receptor ligand mapping by directed phage display

Background: A rapid phage display method for the elucidation of cognate peptide specific ligand for receptors is described. The approach may be readily integrated into the interface of genomic and proteomic studies to identify biologically relevant ligands.Methods: A gene fragment library from influenza coat protein haemagglutinin (HA) gene was constructed by treating HA cDNA with DNAse I to create 50 ¿ 100 bp fragments. These fragments were cloned into plasmid pORFES IV and in-frame inserts were selected. These in-frame fragment inserts were subsequently cloned into a filamentous phage display vector JC-M13-88 for surface display as fusions to a synthetic copy of gene VIII. Two well characterized antibodies, mAb 12CA5 and pAb 07431, directed against distinct known regions of HA were used to pan the library. Results: Two linear epitopes, HA peptide 112 ¿ 126 and 162¿173, recognized by mAb 12CA5 and pAb 07431, respectively, were identified as the cognate epitopes.Conclusion: This approach is a useful alternative to conventional methods such as screening of overlapping synthetic peptide libraries or gene fragment expression libraries when searching for precise peptide protein interactions, and may be applied to functional proteomics.

De llibertat, autoritat i in/dependències (a la vida i l'obra de Maria-Mercè Marçal)

This article pays attention to two moments in the life and work (inseparably united) of Maria-Mercè Marçal. The first refers to a search of small objects presided by the moon. Taking this search as a motif, the freedom which the poet confers to the nocturnal light ¿mythical and magical symbol of femaleness- and, therefore, to that which symbolises the heavenly body, is revealed. The second moment revolves around the reflection of Marçal on the ¿female authority¿, a concept which this author, inspired by the philosophical community of Diotima, distinguishes from power. Throughout history, Maria-Mercè Marçal remarked, many women have gained strength from the free atribution of authority to other women, to their texts, to their experiences.