51 resultados para Carreggio, Antonio Allegri, known as, 1494-1534.


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Increased plasma levels of cholesterol are high risk factors of cardiovascular disease. Statins are drugs that inhibit cholesterol synthesis at both pancreatic and extrahepathic levels, being the treatment of choice for hypercholesterolemia. Objective: To analyze the side effects of statins in the mouth cavity, and to analyze the symptoms after interruption of the treatment. Design: Observational study, preliminary. Material and methods: Patients aged 50-70, diagnosed with hypercholesterolemia and undergoing treatment with statins, referred from their primary care physician to the dentist"s office. Anamnesis over oral symptoms was performed in the first visit. Statin treatment was discontinued, followed by lab tests and control visits seven and fifteen days later. We monitored the improvement and/or remission of oral symptoms. Statin treatment was resumed, sending out a report of the patient evolution to the PCP. Symptoms were registered in sheet specially designed for the study. Exclusion criteria: patient refusal, use of drugs for dry mouth treatment, Sjögren"s syndrome. Results: n=26 patients. Dry mouth patients: improvement in 17 out of 23 patients (88.5%). Itchiness: 6 out of 15 cases improved (57.7%). Bitterness: improvement in 13 out of 14 patients (53.8%). Cough: improvement in 11 out of 12 patients (46.1%). Discussion: A high percentage of oral symptoms are associated to treatment with statins. There is a marked improvement after temporary interruption of the treatment. Little is known regarding the side effects of oral treatment with statins. This preliminary study includes a relatively small number of patients. The design of experimental treatments will be required to establish a true correlation between statin treatment and oral symptoms

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One of the most striking results of the human (and mammalian) genomes is the low number of protein-coding genes. To-date, the main molecular mechanism to increase the number of different protein isoforms and functions is alternative splicing. However, a less-known way to increase the number of protein functions is the existence of multifunctional, multitask, or ‘‘moonlighting’’, proteins. By and large, moonlighting proteins are experimentally disclosed by serendipity. Proteomics is becoming one of the very active areas of biomedical research, which permits researchers to identify previously unseen connections among proteins and pathways. In principle, protein–protein interaction (PPI) databases should contain information on moonlighting proteins and could provide suggestions to further analysis in order to prove the multifunctionality. As far as we know, nobody has verified whether PPI databases actually disclose moonlighting proteins. In the present work we check whether well-established moonlighting proteins present in PPI databases connect with their known partners and, therefore, a careful inspection of these databases could help to suggest their different functions. The results of our research suggest that PPI databases could be a valuable tool to suggest multifunctionality.

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Nos encontramos en un momento de transformación estructural de la sociedad. Mientras desde elpoder se lleva a cabo una transición hacia un lugar que nos ha traído a un contexto de crisis, desdela calle se plantean transiciones hacia nuevas fórmulas de relacionarse, de hacer política, de trabajar,de pensar la economía.La literatura no puede ser ajena a este contexto, como tampoco lo ha sido en otros momentos en losque el pueblo trataba de generar cambios profundos en la sociedad. En este momento esespecialmente interesante preguntarse por el compromiso del autor en la literatura.

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This paper provides a systematic approach to theproblem of nondata aided symbol-timing estimation for linearmodulations. The study is performed under the unconditionalmaximum likelihood framework where the carrier-frequencyerror is included as a nuisance parameter in the mathematicalderivation. The second-order moments of the received signal arefound to be the sufficient statistics for the problem at hand and theyallow the provision of a robust performance in the presence of acarrier-frequency error uncertainty. We particularly focus on theexploitation of the cyclostationary property of linear modulations.This enables us to derive simple and closed-form symbol-timingestimators which are found to be based on the well-known squaretiming recovery method by Oerder and Meyr. Finally, we generalizethe OM method to the case of linear modulations withoffset formats. In this case, the square-law nonlinearity is foundto provide not only the symbol-timing but also the carrier-phaseerror.

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A regularization method based on the non-extensive maximum entropy principle is devised. Special emphasis is given to the q=1/2 case. We show that, when the residual principle is considered as constraint, the q=1/2 generalized distribution of Tsallis yields a regularized solution for bad-conditioned problems. The so devised regularized distribution is endowed with a component which corresponds to the well known regularized solution of Tikhonov (1977).

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Ressenya del llibre 'Turismo cultural. Entre la experiencia y el ritual', escrit per José Antonio Donaire Benito, publicat l'any 2012 per edicions Vitel·la

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En 2008 y en dos ocasiones, la Sala Primera del Tribunal Supremo ha resuelto la cuestión relativa a si el propietario de una finca, la cual había contaminado como consecuencia del desarrollo de su actividad industrial y había vendido ocultando esta circunstancia, es responsable extracontractualmente frente al tercer adquirente por los daños económicos sufridos. En la primera Sentencia, de 29.10.2008, el Tribunal Supremo condena al contaminador por responsabilidad extracontractual. En la segunda, de 22.12.2008, el Tribunal Supremo absuelve a éste de la responsabilidad extracontracual porqué los daños fueron causados a una finca propia.

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La STS, 1a, 21.11.2008, objeto de este comentario, plantea a un tiempo la responsabilidad del consumidor, vendedor, fabricante y Administración pública por los daños materiales causados por la explosión de un producto altamente inflamable que había sido vendido a un particular para la desinfección de su vivienda.

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La nota vol donar a conèixer l’exemplar de les Transformacions ovidianes, en versió de Francesc Alegre, custodiat a “La Casa del Libro”, museu instal·lat a San Juan de Puerto Rico.

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Santiago Ramón y Cajal developed a great body of scientific research during the last decade of 19th century, mainly between 1888 and 1892, when he published more than 30 manuscripts. The neuronal theory, the structure of dendrites and spines, and fine microscopic descriptions of numerous neural circuits are among these studies. In addition, numerous cell types (neuronal and glial) were described by Ramón y Cajal during this time using this 'reazione nera' or Golgi method. Among these neurons were the special cells of the molecular layer of the neocortex. These cells were also termed Cajal cells or Retzius cells by other colleagues. Today these cells are known as Cajal-Retzius cells. From the earliest description, several biological aspects of these fascinating cells have been analyzed (e.g., cell morphology, physiological properties, origin and cellular fate, putative function during cortical development, etc). In this review we will summarize in a temporal basis the emerging knowledge concerning this cell population with specific attention the pioneer studies of Santiago Ramón y Cajal.

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[spa]En este artículo planteamos que significaron los trabajos de los arquitectos Ramon y Antoni Puig Gairalt, que abarcan desde la primera década del siglo XX hasta el año 1937 y que aún perviven en muchas de las localidades del territorio catalán donde intervinieron. Hablamos en plural de los Puig Gairalt porque fueron dos hermanos, Ramon y Antoni, aunque en L'Hospitalet de Llobregat las intervencions corresponden mayoritariamente a Ramon Puig Gairalt. En la actualidad muchas de las obras perduran y, como valores patrimoniales, han llegado hasta nosotros. Como es bien sabido, el patrimonio de muchas poblaciones y ciudades forma parte de la memoria con la que una colectividad se identifica. A lo largo del tiempo, han ido conformando su paisaje urbano y cualquier colectividad que transita por su territorio, establece un vínculo muy directo sea éste o no de carácter monumental porque de hecho se ha convertido en signo de su identidad.

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Prof. Dr. Antonio Prevosti was born on the 15th of February, 1919, at Barcelona where he grew up and lived with his wife Maria Monclús and his family until his death. Between the years 1939 and 1942 he registered at the University of Barcelona and finished his studies there with the"University Degree in Natural Science" obtaining the extraordinary award of his promotion. Immediately afterwards he started his research about the growth rate of Barcelona school children from two very different social groups at the Anthropology Laboratory of the University of Barcelona. The obtained results were published in his Doctoral Thesis (1948). Further investigations on quantitative traits in human populations improved his knowledge of statistical analyses and provided the basis for a scholarship from the Italian Ministry of Foreign Affairs to work at the Institute of Statistical and Demographical Sciences in Rome directed by Prof. C. Gini.

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Este volumen, publicado por la Universidad de Navarra y la editorial Iberoamerica-Vervuert, recoge las contribuciones realizadas durante el encuentro celebrado en Lima, del 5 al 7 de abril de 2006, en el que , bajo la organización del Instituto Riva-Agüero de la Pontificia Universidad Católica del Perú y del Grupo de Investigación Siglo de Oro de la Universidad de Navarra, numerosos especialistas pusieron en común el resultado de sus investigaciones sobre el teatro colonial hispanoamericano.