Aproximación a las fuentes bibliográficas de interés en Ortodoncia II

Segunda parte y final de las fuentes bibliográficas más importantes para el estudio de la ortodoncia, como ciencia de la salud. Aquí se relacionan las publicaciones periódicas, específicas y generales, tesis y videos.

Diagnóstico radiológico de un cuerpo extraño en fosas nasales. A propósito de un caso con retraso de erupción de incisivos laterales.

Se presenta el caso de un paciente con un objeto inanimado en fosa nasal izquierda, que acudió a la Clínica Odontológica de Bellvitge, por la ausencia de los incisivos laterales permanentes en el maxilar superior. Al confirmar la presencia de los incisivos, a partir de una radiografía oclusal, descubrimos, de forma casual, un objeto radiopaco al que acompañaba una específica sintomatología. Después de la intervención del otorrinolaringólogo, dicha sintomatología desapareció. Referimos el manejo de los cuerpos extraños en fosas nasales y aprovechamos la ocasión para revisar las pautas generales de orientación diagnóstico-terapéuticas frente a esta patología.

Aproximación a las fuentes bibliográficas de interés en Ortodoncia I

Se exponen las fuentes bibliográficas más importantes para el estudio de la ortodoncia, como ciencia de la salud, que viene a complementar el anterior artículo sobre "Fuentes documentales de la ortodoncia". Se relaciona la bibliografía ortodóncica aparecida en España.

Prevalencia de caries y estado periodontal de los niÑos y adolescentes de Navarra (2002)

Introducción (fundamento y objetivo): En Navarra se realiza un seguimiento epidemiológico de la caries dental y su tratamiento desde el año 1987, antes de la puesta en marcha del programa PADI en 1991. El objetivo de este trabajo ha sido conocer el estado de salud dental y periodontal de la población infantil y adolescente de Navarra en 2002. Método: Encuesta epidemiológica sobre una muestra al azar de escolares de 1º, 3º y 6º de Enseñanza Primaria y 2º ESO, de 1566 sujetos. Los exámenes clínicos fueron realizados por examinadores calibrados (Kappa 0,93) en los colegios utilizando equipamiento portátil. El estudio estadístico se realizó con una base de datos Microsoft Acces, con el paquete estadístico SPSS versión 10 para Windows. Resultados: La prevalencia de caries en dentición temporal a los 6 años fue de 35,4% (cod 1,28) y en permanente a los 14 años 50,7%. La media CAOD en los cuatro grupos etarios fue 0,04; 0,27; 0,75 y 1,36 respectivamente. Los índices de restauración (IR) 16,7%, 48,1%, 77,3% y 78,7%. El estado periodontal, sanos (6 sext. ) 9,1%, sangrado 86,3%, cálculo 17,2%. Conclusión: La prevalencia de caries sigue siendo alta pero la media de dientes afectados baja; la tendencia respecto de 1997 es a aumentar en dentición temporal y a disminuir en permanente.

New strategies in the modulation of fatty acid oxidation as a treatment for obesity

Strategies that enhance fat degradation or reduce caloricfood intake could be considered therapeutic interventions to reduce notonly obesity, but also its associated disorders. The enzyme carnitinepalmitoyltransferase 1 (CPT1) is the critical rate-determining regulatorof fatty acid oxidation (FAO) and might play a key role in increasingenergy expenditure and controlling food intake. Our group has shownthat mice overexpressing CPT1 in liver are protected from weight gain,the development of obesity and insulin resistance. Regarding foodintake control, we observed that the pharmacological inhibition ofCPT1 in rat hypothalamus decreased food intake and body weight.This suggests that modulation of CPT1 activity and the oxidation offatty acids in various tissues can be crucial for the potential treatmentof obesity and associated pathologies.

Introducción a la farmacia galénica: un reto en primer año de farmacia

[spa] Este curso académico 2009-2010 se implanta el nuevo plan de estudios de Farmacia en la Universidad de Barcelona, diseñado según los planteamientos del EEES. Como consecuencia, y por primera vez en la historia de la Facultad de Farmacia de la UB, se imparte una asignatura troncal de cariz galénico en el primer año de la carrera. Esto constituye un nuevo reto para el Grupo de Innovación Docente de Tecnología Farmacéutica (GIDTF), dado que la asignatura Introducción a la Farmacia Galénica se ha de impartir a grandes grupos de estudiantes, al inicio de su carrera, mediante sesiones teóricas de 1,5 h. Excepcionalmente en este curso académico, la asignatura se imparte en el primer semestre y se repite en el segundo. En este trabajo se presenta el planteamiento metodológico presencial diseñado para esta asignatura, apoyado en estrategias no presenciales como foro de debate, recursos on-line, cuestionarios y tareas de autoevaluación a través de la plataforma Moodle del Campus Virtual de la UB, puesto que el equipo docente considera prioritario iniciar al estudiante en el uso de la misma en el primer año de carrera. Se han efectuado encuestas de satisfacción a los estudiantes que se han evaluado, así también como los resultados académicos obtenidos. En el análisis de los puntos fuertes y débiles de la metodología empleada, se han detectado evaluaciones positivas y también aspectos que podrían mejorarse, estableciendo las medidas correctoras adecuadas. En cuanto a los resultados académicos, han sido muy satisfactorios. [eng] This academic year 2009-2010, the new curriculum of Pharmacy according to the premises of the EHEA is started at the University of Barcelona. As a result, for the first time in the history of the Faculty of Pharmacy of UB, an obligatory galenic subject will be given during the first year of the career. This is a new challenge for Teaching Innovation Group of Pharmaceutical Technology (GIDTF), as the subject Introduction to Galenic Pharmacy is given by a team of teachers to large groups of students who began its career, through theoretical sessions of 1.5 h. The subject will be taught exceptionally this academic year in the first semester and repeated in the second. In this paper we present the methodological approach designed to face this subject, supported by virtual strategies as discussion forum, online resources, self-assessment test and work through the platform Moodle of the Virtual Campus UB, as the team considers it a priority to initiate the student in using it in the first year of pharmacy study. Were carried out satisfaction surveys to students and we have evaluated them, as well as academic performance. Through the analysis of the methodology, we detected positive evaluations and areas for improvement that have been used to establish appropriate corrective measures. Academic results have been very satisfactory.

Analyzing peptides and proteins by mass spectrometry: principles and applications in proteomics

The study of proteins has been a key element in biomedicine and biotechnology because of their important role in cell functions or enzymatic activity. Cells are the basic unit of living organisms, which are governed by a vast range of chemical reactions. These chemical reactions must be highly regulatedin order to achieve homeostasis. Proteins are polymeric molecules that havetaken on the evolutionary process the role, along with other factors, of controlthese chemical reactions. Learning how proteins interact and control their up anddown regulations can teach us how living cells regulate their functions, as well asthe cause of certain anomalies that occur in different diseases where proteins areinvolved. Mass spectrometry (MS) is an analytical widely used technique to studythe protein content inside the cells as a biomarker point, which describesdysfunctions in diseases and increases knowledge of how proteins are working.All the methodologies involved in these descriptions are integrated in the fieldcalled Proteomics.

Spatial Exploration of Age Distribution in Catalan Municipalities

This paper takes the shelf and digs into the complex population’s age structure of Catalan municipalities for the year 2009. Catalonia is a very heterogeneous territory, and age pyramids vary considerably across different areas of the territory, existing geographical factors shaping municipalities’ age distributions. By means of spatial statistics methodologies, this piece of research tries to assess which spatial factors determine the location, scale and shape of local distributions. The results show that there exist different distributional patterns across the geography according to specific local determinants. Keywords: Spatial Models. JEL Classification: C21.

Migration Determinants at a Local Level

This paper is about determinants of migration at a local level. We use data from Catalan municipalities in order to understand what explains migration patterns trying to identify whether they are main explained by amenities or economic characteristics. We distinguish three typologies of migration in terms of distance travelled: short-distance, short-medium-distance and medium-distance and we hypothesize whether migration determinants vary across these groups. Our results show that, effectively, there are some noticeable differences, suggest that spatial issues must be taken into account and provide some insights for future research. Keywords: population dynamics, spatial econometrics. JEL codes: C21, R0, R23

A nuclear defect in the 4p16 region predisposes to multiple mitochondrial DNA deletions in families with Wolfram syndrome.

Wolfram syndrome is a progressive neurodegenerative disorder transmitted in an autosomal recessive mode. We report two Wolfram syndrome families harboring multiple deletions of mitochondrial DNA. The deletions reached percentages as high as 85-90% in affected tissues such as the central nervous system of one patient, while in other tissues from the same patient and from other members of the family, the percentages of deleted mitochondrial DNA genomes were only 1-10%. Recently, a Wolfram syndrome gene has been linked to markers on 4p16. In both families linkage between the disease locus and 4p16 markers gave a maximum multipoint lod score of 3.79 at theta = 0 (Pi<0.03) with respect to D4S431. In these families, the syndrome was caused by mutations in this nucleus-encoded gene which deleteriously interacts with the mitochondrial genome. This is the first evidence of the implication of both genomes in a recessive disease.

A nuclear defect in the 4p16 region predisposes to multiple mitochondrial DNA deletions in families with Wolfram syndrome.

Wolfram syndrome is a progressive neurodegenerative disorder transmitted in an autosomal recessive mode. We report two Wolfram syndrome families harboring multiple deletions of mitochondrial DNA. The deletions reached percentages as high as 85-90% in affected tissues such as the central nervous system of one patient, while in other tissues from the same patient and from other members of the family, the percentages of deleted mitochondrial DNA genomes were only 1-10%. Recently, a Wolfram syndrome gene has been linked to markers on 4p16. In both families linkage between the disease locus and 4p16 markers gave a maximum multipoint lod score of 3.79 at theta = 0 (Pi<0.03) with respect to D4S431. In these families, the syndrome was caused by mutations in this nucleus-encoded gene which deleteriously interacts with the mitochondrial genome. This is the first evidence of the implication of both genomes in a recessive disease.

Precios implícitos de los atributos de los productos turísticos: ¿Qué esconde el efecto de la localización?

Different studies have decomposed the prices of tourism products into the implicit prices of their attributes (category and services), location and time of the year. These studies usually consider location as a residual indicator of the environment surrounding the tourism product, that is, an indicator unexplained by the model and which includes several elements. This paper analyses in-depth the factors which, according with previous studies, might be include in the variable “location”, such as natural capital; cultural, gastronomic and sportive supply; or public goods and services

New strategies in the modulation of fatty acid oxidation as a treatment for obesity

Strategies that enhance fat degradation or reduce caloricfood intake could be considered therapeutic interventions to reduce notonly obesity, but also its associated disorders. The enzyme carnitinepalmitoyltransferase 1 (CPT1) is the critical rate-determining regulatorof fatty acid oxidation (FAO) and might play a key role in increasingenergy expenditure and controlling food intake. Our group has shownthat mice overexpressing CPT1 in liver are protected from weight gain,the development of obesity and insulin resistance. Regarding foodintake control, we observed that the pharmacological inhibition ofCPT1 in rat hypothalamus decreased food intake and body weight.This suggests that modulation of CPT1 activity and the oxidation offatty acids in various tissues can be crucial for the potential treatmentof obesity and associated pathologies.

Relación precio-calidad de los destinos turísticos españoles de sol y playa

The aim of this article is to estímate price-quality relatíon of Spain resorts from ‘sun and beach’ segment. This study uses initially observed prices, but after obtains net pnces -estimated-, discounting services and characteristics prices. Methodologically, this article is based in hedonic methods, often used in economic analysis. Results show important differences between ‘prices observed’ and ‘adjusted prices’ by services and characteristics. Empirical results obtained in this article should be useful for taking decisions from public and prívate agents

Registre telemàtic per administracions públiques

El projecte neix amb la finalitat de reduir aquests costos, creant una infraestructura que permeti realitzar els tràmits amb les Administracions Públiques per via telemàtica. D'aquesta forma se suprimeix la necessitat d'acudir presencialment a una oficina de l'Administració, suposant una gran avantatge per ambdues parts, especialment en quant al cost temporal.