20 resultados para osteogenic differentiation


Relevância:

20.00% 20.00%

Publicador:

Resumo:

[cat] En aquest treball, s'estudia si la hiptesi de la desigualtat efectivament mantinguda effectively maintained inequality es cumpleix a Espanya. Es postula que en les transicions terciries a Espanya, les influncies dels pares no es manifesten tant a travs de la probabilitat de fer la transici, sin ms aviat a travs de les diferncies qualitatives associades a aquesta transici en termes de les qualitats dels programes educatius. Analitzem dues caracterstiques qualitatives dels estudis universitaris: la durada del programa i el seu prestigi acadmic. Identifiquem per a quins individus la influncia parental s ms important en cada cas.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Liver is unique in its capacity to regenerate in response to injury or tissue loss. Hepatocytes and other liver cells are able to proliferate and repopulate the liver. However, when this response is impaired, the contribution of hepatic progenitors becomes very relevant. Here, we present an update of recent studies on growth factors and cytokine-driven intracellular pathways that govern liver stem/progenitor cell expansion and differentiation, and the relevance of these signals in liver development, regeneration and carcinogenesis. Tyrosine kinase receptor signaling, in particular, c-Met, epidermal growth factor receptors or fibroblast growth factor receptors, contribute to proliferation, survival and differentiation of liver stem/progenitor cells. Different evidence suggests a dual role for the transforming growth factor (TGF)- signaling pathway in liver stemness and differentiation. On the one hand, TGF- mediates progression of differentiation from a progenitor stage, but on the other hand, it contributes to the expansion of liver stem cells. Hedgehog family ligands are necessary to promote hepatoblast proliferation but need to be shut off to permit subsequent hepatoblast differentiation. In the same line, the Wnt family and -catenin/T-cell factor pathway is clearly involved in the maintenance of liver stemness phenotype, and its repression is necessary for liver differentiation during development. Collectively, data indicate that liver stem/progenitor cells follow their own rules and regulations. The same signals that are essential for their activation, expansion and differentiation are good candidates to contribute, under adequate conditions, to the paradigm of transformation from a pro-regenerative to a pro-tumorigenic role. From a clinical perspective, this is a fundamental issue for liver stem/progenitor cell-based therapies.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

The loss of species during the Holocene was, dramatically more important on islands than on continents. Seabirds from islands are very vulnerable to human-induced alterations such as habitat destruction, hunting and exotic predators. For example, in the genus Puffinus (family Procellariidae) the extinction of at least five species has been recorded during the Holocene, two of them coming from the Canary Islands.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Modeling ecological niches of species is a promising approach for predicting the geographic potential of invasive species in new environments. Argentine ants (Linepithema humile) rank among the most successful invasive species: native to South America, they have invaded broad areas worldwide. Despite their widespread success, little is known about what makes an area susceptible - or not - to invasion. Here, we use a genetic algorithm approach to ecological niche modeling based on high-resolution remote-sensing data to examine the roles of niche similarity and difference in predicting invasions by this species. Our comparisons support a picture of general conservatism of the species' ecological characteristics, in spite of distinct geographic and community contexts

Relevância:

20.00% 20.00%

Publicador:

Resumo:

El gnere Ophidion esta representat al Mediterrani per dues espcies, 0. barbatum L. i O.rochei Mller. Sn dues espcies molt similars en aspecte i difcils d'identificar noms apartir dels seus carcters morfolgics externs. El treball descriu en primer lloc, i a partir de dades obtingudes per tcniques electrofortiques, alguns marcadors bioqumics que permetendiferenciar les dues espcies. En segon lloc, i a partir del clcul de la 'Distncia Genticade Nei', es fa una estimaci del temps de divergncia entre O. barbatum i 0. rochei