Purification of complex biopharmaceuticals with new processes, advanced analytics and computer-aided process design tools

Dissertação para obtenção do Grau de Mestre em Biotecnologia

On-line system for faults detection in induction motors based on PCA

Dissertation to obtain the degree of Master in Electrical and Computer Engineering

Desenvolvimento de uma plataforma de informação para orçamentação de produtos únicos: aplicação na industria de cablagens

O desenvolvimento da tecnologia informática e de melhor hardware, proporcionou ao mercado de aplicações informáticas, um grande crescimento nas últimas décadas. Paralelamente, o aprofundamento e investigação das disciplinas de engenharia industrial, de novas filosofias e tipologias de produção, proporcionam ao mercado de sistemas de informação, uma panóplia de soluções abrangentes a todos os sectores e departamentos das organizações. Apesar da grande oferta, nem sempre existe viabilidade financeira das organizações para adquirirem e/ ou implementarem uma solução eficaz que responda às suas necessidades específicas. A presente dissertação, incide na melhoria do sistema de orçamentação do produto numa indústria de produtos únicos, através de uma plataforma de informação que permita reduzir o tempo de elaboração, melhorando a estimação do tempo de produção. As exigências do mercado em causa, influenciadas pela concorrência de países com mão-de-obra mais barata, prazos de resposta a orçamentos muito curtos e pequenas margens de negociação e lucro, implicam a necessidade de que sejam minimizadas ao máximo as atividades sem valor acrescentado, como o caso da orçamentação. Foi elaborada uma análise à empresa, ao produto - cablagem, às operações e seus recursos em estudo de caso. Após o levantamento das operações de produção executadas na empresa, reuniram-se os tempos referentes aos tempos de elaboração de cada operação, tendo sido estes utilizados para melhorar a estimativa do tempo de produção. A plataforma de informação foi desenvolvida seguindo o processo produtivo de cablagens, princípios de orçamentação e algumas funcionalidades referentes a ferramentas de apoio à produção, tais como, Product Data Management, Computer Aided Design, Bill-of-Material e Visual Aid’s. Estruturada consoante as necessidades da empresa e respeitando a vasta gama de Matérias- Primas intervenientes na produção, a ferramenta desenvolvida proporcionou a redução do tempo de orçamentação e melhoria na estimativa dos tempos de produção. Esta ferramenta é no entanto transversal e com pequenas alterações, poderá ser implementada em qualquer outra indústria de produtos únicos.

Fatigue life assessment of endodontic instruments subjected to multi planar curvature

This present study aimed to investigate the fatigue life of unused (new) endodontic instruments made of NiTi with control memory by Coltene™ and subjected to the multi curvature of a mandibular first molar root canal. Additionally, the instrument‟s structural behaviour was analysed through non-linear finite element analysis (FEA). The fatigue life of twelve Hyflex™ CM files was assessed while were forced to adopt a stance with multiple radius of curvature, similar to the ones usually found in a mandibular first molar root canal; nine of them were subjected to Pecking motion, a relative movement of axial type. To achieve this, it was designed an experimental setup with the aim of timing the instruments until fracture while worked inside a stainless steel mandibular first molar model with relative axial motion to simulate the pecking motion. Additionally, the model‟s root canal multi-curvature was confirmed by radiography. The non-linear finite element analysis was conducted using the computer aided design software package SolidWorks™ Simulation, in order to define the imposed displacement required by the FEA, it was necessary to model an endodontic instrument with simplified geometry using SolidWorks™ and subsequently analyse the geometry of the root canal CAD model. The experimental results shown that the instruments subjected to pecking motion displayed higher fatigue life values and higher lengths of fractured tips than those with only rotational relative movement. The finite element non-linear analyses shown, for identical conditions, maximum values for the first principal stress lower than the yield strength of the material and those were located in similar positions to the instrument‟s fracture location determined by the experimental testing results.

A tradução de textos económico-financeiros de português para inglês: potencialidades da Plataforma ISTRION

Este Trabalho de Projeto tem como objetivo primordial analisar a tradução, de português para inglês, de textos económico-financeiros, utilizando a plataforma de Tradução Automática (TA) ISTRION. A tradução de conteúdos selecionados da Newsletter Económico-Financeira Maximus Report é efetuada com base na referida plataforma, complementada com outras ferramentas de apoio ao processamento linguístico que sejam consideradas relevantes. Visa-se igualmente com este Trabalho de Projeto analisar as potencialidades desta plataforma, bem como medir os resultados da tradução. Por último pretende-se enquadrar, testar, estudar e medir quais os critérios em que se poderá tornar mais eficiente a tradução destes textos.

Human-Human Collaboration in Virtual Teams

Extended and networked enterprises distribute the design of products, planning of the production process, and manufacturing regionally if not globally. Employees are therefore confronted with collaborative work over remote sites. A cost effective collaboration depends highly on the organization maintaining a common understanding for this kind of work and a suitable support with information and communication technology. The usual face to face work is going to be replaced at least partly if not totally by computer mediated collaboration. Creating and maintaining virtual teams is a challenge to work conditions as well as technology. New developments on cost-effective connections are providing not only vision and auditory perception but also haptic perception. Research results for improving remote collaboration are presented. Individual, social and cultural aspects are considered as new requirements on the employees of networked and extended enterprises.

Dpws middleware to support agent-based manufacturing control and simulation

Dissertação apresentada na Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa para obtenção do grau de Mestre em Engenharia Electrotécnica e de Computadores

Future gender relations in global restructuring processes case study evidence from knowledge-intensive, manufacturing and service occupations

Global restructuring processes have not only strong implications for European working and living realities, but also have specific outcomes with regard to gender relations. The following contribution analyses in which way global restructuring shapes current gender relations in order to identify important trends and developments for future gender (in)equalities at the workplace. On the basis of a large qualitative study on global restructuring and impacts on different occupational groups it argues that occupational belonging in line with skill and qualification levels are crucial factors to assess the further development of gender relations at work. Whereas global restructuring in knowledge-based occupations may provide new opportunities for female employees, current restructuring is going to deteriorate female labour participation in service occupations. In contrast, manufacturing occupations can be characterised by persistent gender relations, which do not change in spite of major restructuring processes at the work place. Taking the institutional perspective into account, it seems to be crucial to integrate the occupational perspective in order to apply adequate policy regulations to prevent the reinforcement of gender related working patterns in the near future.

Is ambient intelligence a truly human-centric paradigm in industry? Current research and application scenario

Based on the paper presented at the International Conference “Autonomous Systems: inter-relations of technical and societal issues”, organized by IET with the support of the Portuguese-German collaboration project on “Technology Assessment of Autonomous Robotics” (DAAD/CRUP) at FCT-UNL, Biblioteca da UNL, Campus de Caparica on 5-6 November 2009.

MASS CONSERVATION ENHANCEMENT OF FREE BOUNDARY FLOWS IN COMPOSITES MANUFACTURING

Undesirable void formation during the injection phase of the liquid composite molding process can be understood as a consequence of the non-uniformity of the flow front progression, caused by the dual porosity of the fiber perform. Therefore the best examination of the void formation physics can be provided by a mesolevel analysis, where the characteristic dimension is given by the fiber tow diameter. In mesolevel analysis, liquid impregnation along two different scales; inside fiber tows and within the spaces between them; must be considered and the coupling between these flow regimes must be addressed. In such case, it is extremely important to account correctly for the surface tension effects, which can be modeled as capillary pressure applied at the flow front. When continues Galerkin method is used, exploiting elements with velocity components and pressure as nodal variables, strong numerical implementation of such boundary conditions leads to ill-posing of the problem, in terms of the weak classical as well as stabilized formulation. As a consequence, there is an error in mass conservation accumulated especially along the free flow front. This article presents a numerical procedure, which was formulated and implemented in the existing Free Boundary Program in order to significantly reduce this error.

Mass Conservation Enhancement of Free Boundary Mesolevel Flows during LCM Processes of Composites Manufacturing

Undesirable void formation during the injection phase of the liquid composite moulding process can be understood as a consequence of the non-uniformity of the flow front progression, caused by the dual porosity of the fibre perform. Therefore the best examination of the void formation physics can be provided by a mesolevel analysis, where the characteristic dimension is given by the fibre tow diameter. In mesolevel analysis, liquid impregnation along two different scales; inside fibre tows and within the open spaces between them; must be considered and the coupling between these flow regimes must be addressed. In such case, it is extremely important to account correctly for the surface tension effects, which can be modelled as capillary pressure applied at the flow front. Numerical implementation of such boundary conditions leads to ill-posing of the problem, in terms of the weak classical as well as stabilized formulation. As a consequence, there is an error in mass conservation accumulated especially along the free flow front. This contribution presents a numerical procedure, which was formulated and implemented in the existing Free Boundary Program in order to significantly reduce this error.

An agent-based evolutionary approach for manufacturing system layout design

Dissertação apresentada na Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa para obtenção do grau de Mestre em Engenharia Electrotécnica e de Computadores

Dynamics of cork mycobiota throughout stopper manufacturing process: from diversity to metabolite

Dissertation presented to obtain the Ph.D degree in Biology

Computer-supported cooperative work:alguns temas de investigação

Os primeiros trabalhos sobre Computer-Supported Cooperative Work surgiram na segunda metade da década de 80, estabelecendo-se um campo de investigação interdisciplinar com enfoque no papel do computador e das tecnologias da comunicação no apoio do trabalho em grupo (Ishii et al., 1994). Ao abordar esta área de investigação torna-se claro que é necessário ter em conta a diversidade dos grupos e das tarefas que estes devem de utilizar, entre outros factores importantes. As implicações desta diversidade são discutidas ao nível concepção de interfaces de groupware, em que um maior envolvimento dos utilizadores nas fases iniciais parece ser necessário, e ao nível dos Sistemas de Apoio à Decisão em Grupo.

Melhoria energética do sector de soda leve conforme a nova metodologia manufacturing excellence solvay Portugal

Dissertação para obtenção do Grau de Mestre em Engenharia Química e Bioquímica