9 resultados para Bacterial


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Dissertation presented to obtain the Ph.D degree in Biology by Universidade Nova de Lisboa, Instituto de Tecnologia Química e Biológica, Instituto Gulbenkian de Ciência.

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Biochemistry, 2004, 43 (46), pp 14566–14576 DOI: 10.1021/bi0485833

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Dissertação para obtenção do Grau de Doutor em Engenharia Química e Bioquímica

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Dissertation presented to obtain the Ph.D degree in Biology

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Dissertation presented to obtain the Ph.D degree in Biology.

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Dissertation presented in partial fulfilment of the Requirements for the Degree of Master in Biotechnology

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Dissertation presented to obtain the Ph.D degree in Biology, Microbial Biology

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Sporulation in Bacillus subtilis culminates with the formation of a dormant endospore. The endospore (or spore) is one of the most resilient cell types known and can remain viable in the environment for extended periods of time. Contributing to the spore’s resistance and its ability to interact with and monitor its immediate environment is the coat, the outermost layer of B. subtilis spores. The coat is composed by over 70 different proteins, which are produced at different stages in sporulation and orderly assembled around the developing spore.(...)

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Salmonella enterica serovars are Gram-negative facultative intracellular bacterial pathogens that infect a wide variety of animals. Salmonella infections are common in humans, causing usually typhoid fever and gastrointestinal diseases. Salmonella enterica serovar Typhimurium (S. Typhimurium), which is a leading cause of human gastroenteritis, has been extensively used to study the molecular pathogenesis of Salmonella, because of the availability of sophisticated genetic tools, and of suitable animal and tissue culture models mimicking different aspects of Salmonella infections.(...)