68 resultados para potential loss


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Dissertation to obtain the degree of master in Bioorganic

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This dissertation is presented to obtain a Master degree in Structural and Functional Biochemistry

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J Biol Inorg Chem (2007) 12:777–787 DOI 10.1007/s00775-007-0229-7

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A Work Project, presented as part of the requirements for the Award of a Masters Degree in Finance from the NOVA – School of Business and Economics

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A Work Project, presented as part of the requirements for the Award of a Masters Degree in Management from the NOVA – School of Business and Economics

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Proceedings IGLC-18, July 2010, Technion, Haifa, Israel

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A Work Project, presented as part of the requirements for the Award of a Masters Degree in Management from the NOVA – School of Business and Economics

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Dissertation presented to obtain the Ph.D degree in Biochemistry

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Dissertation for applying to a Master’s Degree in Molecular Genetics and Biomedicine submitted to the Sciences and Technology Faculty of New University of Lisbon

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Immunological tolerance, that is, the failure to mount an immune response to an otherwise immunogenic molecule, is one of the fundamental questions in immunology. The fact that lymphocytes express antigen receptors that are generated randomly and have the potential to recognize any conceivable antigen, adds another puzzle to the physiology of immunological tolerance. The other side of the coin, the general absence of immune responses to self antigens, is ensured by a tight regulation and several selection steps during T and B cell differentiation. One of these processes is the differentiation of regulatory T cells (Treg). While developing in the thymus, T cell clones bearing receptors with high affinity/avidity to antigens present at the time of differentiation may be eliminated by apoptosis or, alternatively, express Foxp3 and become Treg. Treg are key players in the regulation of immunological tolerance since humans and mice with complete loss of function variants of this gene develop fatal autoimmune conditions early in life.(...)

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Dissertation presented to obtain the PhD degree in Biochemistry, Neurosciences

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Doctorate in Biology, Specialty in Biotechnology

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Dissertation to obtain master degree in Biotechnology

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Dissertation to obtain a Master Degree in Molecular Genetics and Biomedicine

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Dissertação para obtenção do Grau de Mestre em Energias Renováveis – Conversão Eléctrica e Utilização Sustentável