Global material analysis on phosphorus flows, supply horizon and impact assessment on phosphorus depletion

Different problems are daily discuss on environmental aspects such acid rain, eutrophication, global warming and an others problems. Rarely do we find some discussions about phosphorus problematic. Through the years the phosphorus as been a real problem and must be more discussed. On this thesis was done a global material flow analysis of phosphorus, based on data from the year 2004, the production of phosphate rock in that year was 18.9 million tones, almost this amount it was used as fertilizer on the soil and the plants only can uptake, on average, 20% of the input of fertilizer to grow up, the remainder is lost for the phosphorus soil. In the phosphorus soil there is equilibrium between the phosphorus available to uptake from the plants and the phosphorus associate with other compounds, this equilibrium depends of the kind of soil and is related with the soil pH. A reserve inventory was done and we have 15,000 million tones as reserve, the amount that is economical available. The reserve base is estimated in 47,000 million tones. The major reserves can be found in Morocco and Western Sahara, United Sates, China and South Africa. The reserve estimated in 2009 was 15,000 million tone of phosphate rock or 1,963 million tone of P. If every year the mined phosphate rock is around 22 Mt/yr (phosphorus production on 2008 USGS 2009), and each year the consumption of phosphorus increases because of the food demand, the reserves of phosphate rock will be finished in about 90 years, or maybe even less. About the value/impact assessment was done a qualitative analysis, if on the future we don’t have more phosphate rock to produce fertilizers, it is expected a drop on the crops yields, each depends of the kind of the soil and the impact on the humans feed and animal production will not be a relevant problem. We can recovery phosphorus from different waste streams such as ploughing crop residues back into the soil, Food processing plants and food retailers, Human and animal excreta, Meat and bone meal, Manure fibre, Sewage sludge and wastewater. Some of these examples are developed in the paper.

A new horizon for online teaching and learning

The Polytechnic Institute of Oporto (IPP), which has a solid history of online education and innovation through the use of technology, has been particularly interested and focused on Massive Open Online Courses (MOOC) developments. The aim of this paper is to present the whole process from initial discussions to completion of the “Mathematics Without Limits” MOOC Project that exists in IPP and also to contribute for a change in the way as teaching and learning Mathematics is seen and practiced nowadays. In 2013, IPP developed its own platform, which gave us the opportunity to explore new educational techniques as a pedagogical resource as well as to enhance students’ motivation, through a set of interactive materials at their disposal, totally adapted to their needs. Students lack of motivation is mainly justified by their weak Math preparation, poor consolidated basis on the subject and different backgrounds of the students. To tackle this issue and based on our Math online courses teaching experience, we decided to create short duration MOOC, expecting to aid retention of students and also to reverse the path of students giving up on Math by giving them a friendly way of managing their own learning commitment. We also think that this MOOC will be a good approach to level out some math skills among freshmen.

A new horizon for online teaching and learning

The Polytechnic Institute of Oporto (IPP), which has a solid history of online education and innovation through the use of technology, has been particularly interested and focused on Massive Open Online Courses (MOOC) developments. The aim of this paper is to present the whole process from initial discussions to completion of the “Mathematics Without Limits” MOOC Project that exists in IPP and also to contribute for a change in the way as teaching and learning Mathematics is seen and practiced nowadays. In 2013, IPP developed its own platform, which gave us the opportunity to explore new educational techniques as a pedagogical resource as well as to enhance students’ motivation, through a set of interactive materials at their disposal, totally adapted to their needs. Students lack of motivation is mainly justified by their weak Math preparation, poor consolidated basis on the subject and different backgrounds of the students. To tackle this issue and based on our Math online courses teaching experience, we decided to create short duration MOOC, expecting to aid retention of students and also to reverse the path of students giving up on Math by giving them a friendly way of managing their own learning commitment. We also think that this MOOC will be a good approach to level out some math skills among freshmen.

A New horizon for online teaching and learning

The Polytechnic Institute of Oporto (IPP), which has a solid history of online education and innovation through the use of technology, has been particularly interested and focused on Massive Open Online Courses (MOOC) developments. The aim of this paper is to present the whole process from initial discussions to completion of the “Mathematics Without Limits” MOOC Project that exists in IPP and also to contribute for a change in the way as teaching and learning Mathematics is seen and practiced nowadays. In 2013, IPP developed its own platform, which gave us the opportunity to explore new educational techniques as a pedagogical resource as well as to enhance students’ motivation, through a set of interactive materials at their disposal, totally adapted to their needs. Students lack of motivation is mainly justified by their weak Math preparation, poor consolidated basis on the subject and different backgrounds of the students. To tackle this issue and based on our Math online courses teaching experience, we decided to create short duration MOOC, expecting to aid retention of students and also to reverse the path of students giving up on Math by giving them a friendly way of managing their own learning commitment. We also think that this MOOC will be a good approach to level out some math skills among freshmen.

As oportunidades de financiamento 2014-2020 e a sua importância para as empresas - Relatório de Estágio na empresa Smarteurope - Funding Solution Company, Lda

Com o presente relatório pretende-se descrever o estágio curricular realizado na entidade Smarteurope – Funding Solution Company, Lda. entre Fevereiro e Dezembro de 2015, entidade que se dedica à prestação de serviços de consultoria e gestão. Este relatório está estruturado em 4 partes fundamentais: enquadramento teórico, apresentação, caracterização e descrição do contexto da organização; descrição das atividades realizadas; e por último a conclusão e reflexão sobre as competências adquiridas.

Short-term wind forecasting for energy resources scheduling

This paper proposes a wind power forecasting methodology based on two methods: direct wind power forecasting and wind speed forecasting in the first phase followed by wind power forecasting using turbines characteristics and the aforementioned wind speed forecast. The proposed forecasting methodology aims to support the operation in the scope of the intraday resources scheduling model, namely with a time horizon of 5 minutes. This intraday model supports distribution network operators in the short-term scheduling problem, in the smart grid context. A case study using a real database of 12 months recorded from a Portuguese wind power farm was used. The results show that the straightforward methodology can be applied in the intraday model with high wind speed and wind power accuracy. The wind power forecast direct method shows better performance than wind power forecast using turbine characteristics and wind speed forecast obtained in first phase.

ß-Lactams: chemical structure, mode of action and mechanisms of resistance

This synopsis summarizes the key chemical and bacteriological characteristics of β-lactams, penicillins, cephalosporins, carbanpenems, monobactams and others. Particular notice is given to first-generation to fifth-generation cephalosporins. This review also summarizes the main resistance mechanism to antibiotics, focusing particular attention to those conferring resistance to broad-spectrum cephalosporins by means of production of emerging cephalosporinases (extended-spectrum β-lactamases and AmpC β-lactamases), target alteration (penicillin-binding proteins from methicillin-resistant Staphylococcus aureus) and membrane transporters that pump β-lactams out of the bacterial cell.

Neurokinin-1 receptor, a new modulator of lymphangiogenesis in obese-asthma phenotype

Aims Obesity and asthma are widely prevalent and associated disorders. Recent studies of our group revealed that Substance P (SP) is involved in pathophysiology of obese-asthma phenotype in mice through its selective NK1 receptor (NK1-R). Lymphangiogenesis is impaired in asthma and obesity, and SP activates contractile and inflammatory pathways in lymphatics. Our aim was to study whether NK1-R expression was involved in lymphangiogenesis on visceral (VAT) and subcutaneous (SAT) adipose tissues and in the lungs, in obese-allergen sensitized mice. Main methods Diet-induced obese and ovalbumin (OVA)-sensitized Balb/c mice were treated with a selective NK1-R antagonist (CJ 12,255, Pfizer Inc., USA) or placebo. Lymphatic structures (LYVE-1 +) and NK1-R expression were analyzed by immunohistochemistry. A semi-quantitative score methodology was used for NK1-R expression. Key findings Obesity and allergen-sensitization together increased the number of LYVE-1 + lymphatics in VAT and decreased it in SAT and lungs. NK1-R was mainly expressed on adipocyte membranes of VAT, blood vessel areas of SAT, and in lung epithelium. Obesity and allergen-sensitization combined increased the expression of NK1-R in VAT, SAT and lungs. NK1-R antagonist treatment reversed the effects observed in lymphangiogenesis in those tissues. Significance The obese-asthma phenotype in mice is accompanied by increased expression of NK1-R on adipose tissues and lung epithelium, reflecting that SP released during inflammation may act directly on these tissues. Blocking NK1-R affects lymphangiogenesis, implying a role of SP, with opposite physiological consequences in VAT, and in SAT and lungs. Our results provide a clue for a novel SP role in the obese-asthma phenotype.

Molecular imprinted nanoelectrodes for ultra sensitive detection of ovarian cancer marker

The relentless discovery of cancer biomarkers demands improved methods for their detection. In this work, we developed protein imprinted polymer on three-dimensional gold nanoelectrode ensemble (GNEE) to detect epithelial ovarian cancer antigen-125 (CA 125), a protein biomarker associated with ovarian cancer. CA 125 is the standard tumor marker used to follow women during or after treatment for epithelial ovarian cancer. The template protein CA 125 was initially incorporated into the thin-film coating and, upon extraction of protein from the accessible surfaces on the thin film, imprints for CA 125 were formed. The fabrication and analysis of the CA 125 imprinted GNEE was done by using cyclic voltammetry (CV), differential pulse voltammetry (DPV) and electrochemical impedance spectroscopy (EIS) techniques. The surfaces of the very thin, protein imprinted sites on GNEE are utilized for immunospecific capture of CA 125 molecules, and the mass of bound on the electrode surface can be detected as a reduction in the faradic current from the redox marker. Under optimal conditions, the developed sensor showed good increments at the studied concentration range of 0.5–400 U mL−1. The lowest detection limit was found to be 0.5 U mL−1. Spiked human blood serum and unknown real serum samples were analyzed. The presence of non-specific proteins in the serum did not significantly affect the sensitivity of our assay. Molecular imprinting using synthetic polymers and nanomaterials provides an alternative approach to the trace detection of biomarker proteins.

Previsão de vento baseado em técnicas de Data Mining

Mestrado em Engenharia Electrotécnica – Sistemas Eléctricos de Energia

Melhoria do processo produtivo na indústria do mobiliário

Com o aumento da concorrência, a crise económica que atravessamos e com a conquista de novos mercados no horizonte, surge a necessidade de responder a essas situações com uma melhor prestação do sistema produtivo no sentido de reduzir tempos de produção e de baixar os custos dos mesmos, podendo assim dar uma resposta mais rápida e competitiva às expectativas dos clientes. Esta dissertação tem como objectivo analisar todo o sistema produtivo da empresa, desenvolvendo um estudo adequado ao sistema actual de fabrico de mobiliário, propondo melhorias que proporcionem uma melhor organização e uma redução dos custos de fabrico. Fez-se também um levantamento do sistema de planeamento existente, detectando pontos de melhoria que, para além de um maior controlo e organização, permitem, em alguns aspectos, a melhoria do sistema produtivo. Foi apresentada uma proposta de um processo de reengenharia aplicado ao sistema produtivo, tendo em vista implementar as medidas de melhoria, indo ao encontro das situações identificadas, tornando assim o sistema produtivo mais eficiente.

CYCLOTech - an innovative approach for the reliable production of 99mTc - technetium

CYCLOTech is a high-tech Project, related with an innovative method for direct production of a radioactive pharmaceutical, used in excess of 85% of 35 Million Nuclear Medicine procedures done yearly, worldwide, representing globally more than 3 Billion Euros. The CYCLOTech team has developed an innovative proprietary methodology based on the use of Cyclotron Centers, formally identified as the Clients (actually, there are around 450 of this Centers in function worldwide), to directly produce and deliver the radiopharmaceutical to the final users, at the Hospitals and other Health Institutions (estimating at around 25.000, worldwide). The investment still need to finish Research and Technological Development (RTD), Industrial, Regulatory and Intellectual Property Rights (IPR) issues and allow the introduction in the Market is 4,35 M€, with a Payback of 3 years, with an Investment Return Rate (IRR) of 81,7% and a Net Present Value (NPV) of 60.620.525€ (in 2020).

Eficiência energética na iluminação pública

A iluminação pública é responsável por 3% do consumo de energia elétrica, em Portugal, tendo havido um crescimento no consumo de energia elétrica neste setor, entre 2000 e 2011, de cerca de 55%, com uma taxa média de crescimento anual de cerca de 5,1%. No ano de 2011, os custos com a iluminação pública rondaram os 170 M€, sendo que grande parte foram assegurados pelos Municípios. Atendendo ao panorama financeiro delicado de grande parte das autarquias do País, e sabendo que a iluminação pública tem um peso considerável nas despesas anuais de energia, faz sentido que se concentre aqui um esforço para tornar mais eficientes estas instalações. A nível nacional, a Estratégia Nacional para a Energia 2020 (ENE 2020) define estratégias que visam o cumprimento das medidas impostas pela União Europeia no sentido de cumprir objetivos que respeitem a sustentabilidade A ENE 2020 define uma agenda para a competitividade, o crescimento e a independência energética e financeira do país através da aposta nas energias renováveis e da promoção integrada da eficiência energética, assegurando a segurança de abastecimento e a sustentabilidade económica e ambiental do modelo energético. Um dos eixos em que se divide a ENE 2020 visa diretamente a promoção da eficiência energética na Iluminação Pública (IP), com o objetivo de promover e apoiar projetos inovadores de iluminação pública com prioridade para os centros históricos. Existem no mercado diversas soluções e tecnologias que permitem melhorar a eficiência energética da IP, facilitando uma gestão mais eficiente. Estes sistemas podem também permitir economias diretas nos consumos de energia e/ou levar a um aumento da vida útil das lâmpadas, permitindo uma redução dos custos de manutenção das instalações de IP.

Potencial de produção de energia eólica em parques offshore

A produção de energia eólica é essencial para o cumprimento dos objetivos europeus, no âmbito das energias renováveis. De acordo com as previsões da União Europeia (UE), a produção hidroelétrica irá manter a sua posição dominante como fonte de energia renovável para a produção de energia elétrica. No entanto, o uso da energia eólica irá continuar a expandir e, em 2020 a capacidade eólica instalada deverá superar o setor hidroelétrico [1]. O setor eólico offshore começa também a dar sinais de interesse por parte de investidores e governantes. No entanto, os investimentos offshore diferem em muito dos investimentos onshore. O planeamento é muito mais complexo e demorado, a construção e manutenção requerem novas soluções e a ligação à rede é um processo exigente. Dada a reduzida experiência das empresas, a incerteza associada ao investimento é elevada. Deste modo, os parques eólicos offshore são uma área de negócio inovadora e de elevado risco, que requerem elevados recursos organizacionais associados frequentemente a grandes empresas do setor da energia. O relatório da Comissão das Comunidades Europeias, destaca a energia eólica offshore como um setor prioritário. Contudo, evidência a necessidade de tempo para o desenvolvimento da tecnologia, assim como, a importância de assegurar à indústria maior segurança e condições de mercado mais estáveis.

Fractional dynamics in financial indexes

The goal of this study is the analysis of the dynamical properties of financial data series from 32 worldwide stock market indices during the period 2000–2009 at a daily time horizon. Stock market indices are examples of complex interacting systems for which a huge amount of data exists. The methods and algorithms that have been explored for the description of physical phenomena become an effective background in the analysis of economical data. In this perspective are applied the classical concepts of signal analysis, Fourier transform and methods of fractional calculus. The results reveal classification patterns typical of fractional dynamical systems.