A divulgação de informação sobre planos de benefícios de reforma em Portugal e a sua relação com o endividamento: Uma análise do PSI geral

Mestrado em Contabilidade e Gestão das Instituições Financeiras

População residente de um hospital psiquiátrico: que saúde visual?

Introdução - Numa tentativa pioneira em Portugal de avaliar o estado da visão dos pacientes residentes de um Hospital Psiquiátrico, foi nosso objectivo identificar alterações visuais existentes nesta população, passíveis de comprometer o funcionamento do sistema visual e com repercussões negativas nas actividades da vida diária; caracterizar e corrigir ametropias; relacionar as patologias encontradas com a medicação e seleccionar! encaminhar os utentes para consulta de oftalmologia. Métodos - Foram examinados 254 pacientes residentes num Hospital Psiquiátrico de Lisboa, com idade compreendida entre os 25 e os 92 anos de idade, com diagnóstico no âmbito da saúde mental, capacidade de deslocação e alguma autonomia. Na recolha de dados foi utilizado o protocolo de observação do rastreio visual, tendo sido avaliados os seguintes parâmetros: Acuidade visual, Estudo refractivo; Função sensório-motora; Visão cromática; Segmento anterior; Tensão ocular. O rastreio foi composto por duas fases: uma primeira fase para identificação das alterações visuais, com 254 residentes e uma segunda fase, com 100 residentes, para correcção das ametropias diagnosticadas e prescrição óptica. Os resultados foram sujeitos a uma análise estatística descritiva e inferencial através do programa SPSS. Resultados - A maioria dos pacientes era do sexo masculino (64,2%), internados principalmente por esquizofrenia (47,24%) e medicados com antipsicóticos (82,8%) mas tomando também anti-parkinsónicos (62,3%) e ansiolíticos (52,4%). Apenas 20,87% da amostra tinha feito anteriormente um exame visual. Além de 33,86% de cataratas, em que 27,4% representam residentes entre os 20 e os 50 anos, encontraram-se acuidades visuais baixas. Para longe, 51% dos indivíduos apresentavam acuidade visual no intervalo entre contar dedos e os 6/10. No que concerne à acuidade visual para perto, os resultados obtidos demonstram que a maioria da população apresenta também baixa acuidade visual, entre os 1/10 e os 3/10, tanto para olho direito (25,59%), como para o olho esquerdo (26,38%). É de referir que esta baixa acuidade visual atinge um total de 27 indivíduos no intervalo dos 40 aos 59 anos. Foi ainda identificado um número expressivo de exoforias para perto (38,58%) e 7,15% de neuropatias glaucomatosas. Do estudo refractivo (2. Fase do rastreio visual), resultou a prescrição de 75 óculos, o que levou a uma melhoria significativa da acuidade visual, principalmente para perto: 50% da amostra que apresentava acuidade visual, no intervalo de percepção luminosa aos 6/10, passou a 3%, após correcção refractiva. No decurso do rastreio 5 residentes foram encaminhadas para o serviço de urgência por neuropatia glaucomatosa e melanoma da coróide. Apenas 5,5% teve alta e os restantes foram encaminhados para consulta de oftalmologia (34% com prioridade). Conclusões - Este rastreio permitiu além da correcção das ametropias diagnosticadas, encaminhar, os residentes com alterações visuais, para tratamento, possibilitando assim, que esta população use a sua visão da melhor maneira e potencializando um aumento da qualidade de vida destes pacientes.

Compact Stars and Magnetized CFL Matter

The stability of the color flavor locked phase in the presence of a strong magnetic field is investigated within the phenomenological MIT bag model. It is found that the minimum value of the energy per baryon in a color flavor locked state at vanishing pressure is lower than the corresponding one for unpaired magnetized strange quark matter and, as the magnetic field increases, the energy per baryon decreases. This implies that magnetized color flavor locked matter is more stable and could become the ground state inside neutron stars. The anisotropy of the pressures is discussed. The mass-radius relation for such stars is also studied.

CVD of CrO2 thin films: Influence of the deposition parameters on their structural and magnetic properties

This work reports on the synthesis of CrO2 thin films by atmospheric pressure CVD using chromium trioxide (CrO3) and oxygen. Highly oriented (100) CrO2 films containing highly oriented (0001) Cr2O3 were grown onto Al2O3(0001) substrates. Films display a sharp magnetic transition at 375 K and a saturation magnetization of 1.92 mu(B)/f.u., close to the bulk value of 2 mu(B)/f.u. for the CrO2.

Fatty acids, IL6, and TNFα polymorphisms: an example of nutrigenetics in Crohn's disease

Objectives - The aim of this work was to study the interaction between genetic polymorphisms (single-nucleotide polymorphisms, SNPs) of pro- and anti-inflammatory cytokines and fat intake on the risk of developing Crohn's disease (CD) or modifying disease activity. Methods - Seven SNPs in interleukin 1 (IL1), tumor necrosis factor alpha (TNFalpha), lymphotoxin alpha (LTalpha), and IL6 genes were analyzed in 116 controls and 99 patients with CD. The type of fat intake was evaluated, and the interaction between SNPs and dietary fat in modulating disease activity was analyzed. Results - Individuals who were homozygous for the IL6-174G/C polymorphism had a six-fold higher risk for CD (odds ratio (OR)=6.1; 95% confidence interval (95% CI)=1.9-19.4), whereas the TT genotype on the TNFalpha-857C/T polymorphism was associated with more active disease (OR=10.4; 95% CI=1.1-94.1). A high intake of total, saturated, and monounsaturated fats, as well as a higher ratio of n-6/n-3 polyunsaturated fatty acid (PUFA), was associated with a more active phenotype (P<0.05). Furthermore, there was an interaction between dietary fat intake and SNPs, with a high intake of saturated and monounsaturated fats being associated with active disease, mainly in patients carrying the variant alleles of the 857 TNFalpha polymorphism (OR=6.0, 95% CI=1.4-26.2; OR=5.17; 95% CI=1.4-19.2, respectively) and the 174 IL6 polymorphism (OR=2.95; 95% CI=1.0-9.1; OR=3.21; 95% CI=1.0-10.4, respectively). Finally, low intake of n-3 PUFA and high n-6/n-3 PUFA ratio in patients with the TNFalpha 857 polymorphism were associated with higher disease activity (OR=3.6; 95% CI=1.0-13.0; OR=5.92; 95% CI=1.3-26.5, respectively). Conclusions - These results show that different types of fat may interact with cytokine genotype, modulating disease activity.

Abelian realization of phenomenological two-zero neutrino textures

In an attempt at explaining the observed neutrino mass-squared differences and leptonic mixing, lepton mass matrices with zero textures have been widely studied. In the weak basis where the charged lepton mass matrix is diagonal, various neutrino mass matrices with two zeros have been shown to be consistent with the current experimental data. Using the canonical and Smith normal form methods, we construct the minimal Abelian symmetry realizations of these phenomenological two-zero neutrino textures. The implementation of these symmetries in the context of the seesaw mechanism for Majorana neutrino masses is also discussed. (C) 2014 The Authors. Published by Elsevier B.V.

InOx thin films deposited by plasma assisted evaporation: application in light shutters

An integration of undoped InOx and commercial ITO thin films into laboratory assembled light shutter devices is made. Accordingly, undoped transparent conductive InOx thin films, about 100 nm thick, are deposited by radiofrequency plasma enhanced reactive thermal evaporation (rf-PERTE) of indium teardrops with no intentional heating of the glass substrates. The process of deposition occurs at very low deposition rates (0.1-0.3 nm/s) to establish an optimized reaction between the oxygen plasma and the metal vapor. These films show the following main characteristics: transparency of 87% (wavelength, lambda = 632.8 nm) and sheet resistance of 52 Omega/sq; while on commercial ITO films the transparency was of 92% and sheet resistance of 83 Omega/sq. The InOx thin film surface characterized by AFM shows a uniform grain texture with a root mean square surface roughness of Rq similar to 2.276 nm. In contrast, commercial ITO topography is characterized by two regions: one smoother with Rq similar to 0.973 nm and one with big grains (Rq similar to 3.617 nm). For the shutters assembled using commercial ITO, the light transmission coefficient (Tr) reaches the highest value (Tr-max) of 89% and the lowest (Tr-min) of 1.3% [13], while for the InOx shutters these values are 80.1% and 3.2%, respectively. Regarding the electric field required to achieve 90% of the maximum transmission in the ON state (E-on), the one presented by the devices assembled with commercial ITO coated glasses is 2.41 V/mu m while the one presented by the devices assembled with InOx coated glasses is smaller, 1.77 V/mu m. These results corroborate the device quality that depends on the base materials and fabrication process used. (C) 2014 Elsevier Ltd. All rights reserved.

Investigation of structural effects and behaviour of pseudomonas aeruginosa amidase encapsulated in reserved micelles

The acetohydroxamic acid synthesis reaction was studied using whole cells, cell-free extract and purified amidase from the strains of Pseudomonas aeruginosa L10 and A13 entrapped in a reverse micelles system composed of cationic surfactant tetradecyltrimethyl ammonium bromide. The specific activity of amidase, yield of synthesis and storage stability were determined for the reversed micellar system as well as for free amidase in conventional buffer medium. The results have revealed that amidase solutions in the reverse micelles system exhibited a substantial increase in specific activity, yield of synthesis and storage stability. In fact, whole cells from P. aeruginosa L10 and AI3 in reverse micellar medium revealed an increase in specific activity of 9.3- and 13.9-fold, respectively, relatively to the buffer medium. Yields of approximately 92% and 66% of acetohydroxamic acid synthesis were obtained for encapsulated cell free extract from P. aeruginosa L10 and A13, respectively. On the other hand, the half-life values obtained for the amidase solutions encapsulated in reverse micelles were overall higher than that obtained for the free amidase solution in buffer medium. Half-life values obtained for encapsulated purified amidase from P. aeruginosa strain L10 and encapsulated cell-free extract from P. aeruginosa strain AI3 were of 17.0 and 26.0 days, respectively. As far as the different sources biocatalyst are concerned, the data presented in this work has revealed that the best results, in both storage stability and biocatalytic efficiency, were obtained when encapsulated cell-free extract from P. aeruginosa strain AI3 at 14/0 of 10 were used. Conformational changes occurring upon encapsulation of both strains enzymes in reverse micelles of TAB in heptane/octanol were additionally identified by FTIR spectroscopy which clarified the biocatalysts performances.

Production, purification and characterisation of polysaccharides from pleurotus ostreatus with antitumor activity

Background: Mushroom polysaccharides play an important role in functional foods because they exhibit biological modulator properties such as antitumour, antiviral and antibacterial activities. The present study involved the production, purification and characterisation of intracellular and extracellular free and protein-bound polysaccharides from Pleurotus ostreatus and the investigation of their growth-inhibitory effect on human carcinoma cell lines. Results: Several fermentation parameters were obtained: batch polysaccharide productivities of 0.013 +/- 8.12 x 10-5 and 0.037 +/- 0.0005 g L-1 day-1 for intracellular and extracellular polysaccharides respectively, a maximum biomass concentration of 9.35 +/- 0.18 g L-1, Pmax = 0.935 +/- 0.018 g L-1 day-1, µmax = 0.218 +/- 0.02 day-1, YEP/X = 0.040 +/- 0.0015 g g-1 and YIP/X = 0.014 +/- 0.0003 g g-1. Some polysaccharides exhibited superoxide dismutase (SOD)-like activity of 50-200 units. Fourier transform infrared analysis of the polysaccharides revealed absorption bands characteristic of such biological macromolecules. Cytotoxicity assays showed that both intracellular and extracellular polysaccharides exhibited antitumour activity towards several tested human carcinoma cell lines in a dose-dependent manner. Conclusion - The polysaccharides of P. ostreatus exhibited high SOD-like activity, which strongly supports their biological effect on tumour cell lines. The extracellular polysaccharides presented the highest antitumour activity towards the RL95 carcinoma cell line and should be further investigated as an antitumour agent.

Is the electric vehicle a solution for the wind power integration in the portuguese power system?

The integration of Plug-in electric vehicles in the transportation sector has a great potential to reduce oil dependency, the GHG emissions and to contribute for the integration of renewable sources into the electricity generation mix. Portugal has a high share of wind energy, and curtailment may occur, especially during the off-peak hours with high levels of hydro generation. In this context, the electric vehicles, seen as a distributed storage system, can help to reduce the potential wind curtailments and, therefore, increase the integration of wind power into the power system. In order to assess the energy and environmental benefits of this integration, a methodology based on a unit commitment and economic dispatch is adapted and implemented. From this methodology, the thermal generation costs, the CO2 emissions and the potential wind generation curtailment are computed. Simulation results show that a 10% penetration of electric vehicles in the Portuguese fleet would increase electrical load by 3% and reduce wind curtailment by only 26%. This results from the fact that the additional generation required to supply the electric vehicles is mostly thermal. The computed CO2 emissions of the EV are 92 g CO2/kWh which become closer to those of some new ICE engines.

Pulsed electric field pre-treatment for apple juice extraction: Evaluation of monopolar and bipolar pulses effects

Additional apple juice extraction with pulsed electric field pretreated apple cubes towards control samples is evaluated. Monopolar and bipolar shaped pulses are compared and their effect is studied with variation of electric field, pulse width and number of pulses. Variation of electric field strength is ranged from 100 V/cm to 1300 V/cm, pulse width from 20 mu s to 300 mu s and number of pulses from 10 to 200, at frequency of 200Hz. Two pulse trains separated by 1 second are applied to all samples. Bipolar pulses showed higher apple juice yields with all studied parameters. Calculation of specific energies consumed was assessed and a threshold where higher energy inputs do not increase juice yield is found for a number of used parameters. Qualitative parameters of total soluble matter (Brix) and absorbance at 390 nm wavelength were determined for each sample and results show that no substantial differences are found for PEF pre-treated and control samples.

Undoubtable signs of CP-violation in Higgs decays at the LHC run 2

With the discovery of the Higgs boson at the Large Hadron Collider the high energy physics community's attention has now turned to understanding the properties of the Higgs boson, together with the hope of finding more scalars during run 2. In this work we discuss scenarios where using a combination of three decays, involving the 125 GeV Higgs boson, the Z boson and at least one more scalar, an indisputable signal of CP-violation arises. We use a complex two-Higgs doublet model as a reference model and present some benchmark points that have passed all current experimental and theoretical constraints, and that have cross sections large enough to be probed during run 2.