Convergence in word structure: revisiting agglutinative noun inflection in Cappadocian Greek

Cappadocian Greek is reported to display agglutinative inflection in its nominal system, namely, mono-exponential formatives for the marking of case and number, and NOM.SG-looking forms as the morphemic units to which inflection applies. Previous scholarship has interpreted these developments as indicating a shift in morphological type from fusion to agglutination, brought about by contact with Turkish. This study takes issue with these conclusions. By casting a wider net over the inflectional system of the language, it shows that, of the two types of agglutinative formations identified, only one evidences a radical departure from the inherited structural properties of Cappadocian noun inflection. The other, on the contrary, represents a typologically more conservative innovation. The study presents evidence that a combination of system-internal and -external motivations triggered the development of both types, it describes the mechanisms through which the innovation was implemented, and discusses the factors that favoured change.

Novel P(3HB) Composite Films Containing Bioactive Glass Nanoparticles for Wound Healing Applications

Bioactive glass (BG) is considered an ideal material for haemostasis as it releases Ca2+ ions upon hydration, which is required to support thrombosis. In this study the effect of the presence of the BG nanoparticles in P(3HB) microsphere films on the structural properties, thermal properties and biocompatibility of the films were studied. The nanoscaled bioactive glass with a high surface area was also tested for its in vitro haemostatic efficacy and was found to be able to successfully reduce the clot detection time. In an effort to study the effect of the roughness induced by the formation of HA on the cellular functions such as cell adhesion, cell mobility and cell differentiation, the composite films were immersed in SBF for a period of 1, 3 and 7 days. From the SEM images the surface of the P(3HB)/n-BG composite microsphere films appeared fairly uniform and smooth on day 1, however on day 3 and day 7 a rough and uneven surface was observed. The presence of HA on the composite microsphere films on day 3 and day 7 influenced the surface roughness of the films. However, when the P(3HB)/n-BG composite microspheres with enhanced surface roughness were tested for biocompatibility, reduced amount of protein adsorption and cell adhesion were observed. This study thus revealed that there is an optimal surface roughness for the P(3HB) microsphere films for increased cell adhesion, beyond which it could be deleterious for cell adhesion and differentiation.