Productividad científica en España sobre las profesiones de comunicación entre 1971 y 2009

A la luz de la Convergencia Europea, los títulos de grado en comunicación elaborados en España están fundamentados en las competencias requeridas para el ejercicio de cada una de las profesiones. Es necesario, pues, analizar al profesional de la Publicidad y las Relaciones Públicas, del Periodismo y de la Comunicación Audiovisual. Este trabajo pretende conocer los estudios de investigación centrados en este tema. Realiza una revisión sistemática de los artículos, libros y tesis doctorales sobre las profesiones de comunicador desde la década de los setenta hasta 2009, en las bases de datos ISOC, ISBN y TESEO. Extrae indicadores bibliométricos y sigue los criterios de evaluación mantenidos por la CNEAI (Comisión Nacional Evaluadora de la Actividad Investigadora) y la ANECA (Agencia Nacional de Evaluación de la Calidad y Acreditación) para valorar las investigaciones. Los resultados muestran que es la firma del Plan Bolonia lo que parece iniciar un ciclo de atención hacia las profesiones de comunicación. Periodismo es la profesión más estudiada. La mayoría de los estudios no cumplen con los criterios de calidad de las agencias evaluadoras. En conjunto, se observa la necesidad de aumentar la cantidad y la calidad de las investigaciones para realizar planes de estudios «basados en evidencia», así como la pertinencia de fortalecer la formación de los investigadores en la metodología de la investigación social.

Simultaneous implementation of the Bachelor, Masters and PhD degrees in nursing in the Universidad Jaume I. Castellón de la Plana, Spain

We present an experience in Nursing Education, accredited and implemented under the Spanish University System Reform in a Public University (Jaume I, Castellón) which had no previous nursing studies. The academics offered included all three educational levels (Bachelor, Master's and Doctorate), with an integrated theoretical-practical-clinical teaching methodology for the Bachelor Degree, competence acquisition in research in the Master's degree, and a doctorate formed by lines of research in the field of Nursing. Studies are accredited by the National Agency for Quality Assessment, which were authorized by the Spanish Ministry of Education and implanted between 2009 and 2011.

Identification of yeast genes that confer resistance to chitosan oligosaccharide (COS) using chemogenomics

Background: Chitosan oligosaccharide (COS), a deacetylated derivative of chitin, is an abundant, and renewable natural polymer. COS has higher antimicrobial properties than chitosan and is presumed to act by disrupting/permeabilizing the cell membranes of bacteria, yeast and fungi. COS is relatively non-toxic to mammals. By identifying the molecular and genetic targets of COS, we hope to gain a better understanding of the antifungal mode of action of COS. Results: Three different chemogenomic fitness assays, haploinsufficiency (HIP), homozygous deletion (HOP), and multicopy suppression (MSP) profiling were combined with a transcriptomic analysis to gain insight in to the mode of action and mechanisms of resistance to chitosan oligosaccharides. The fitness assays identified 39 yeast deletion strains sensitive to COS and 21 suppressors of COS sensitivity. The genes identified are involved in processes such as RNA biology (transcription, translation and regulatory mechanisms), membrane functions (e.g. signalling, transport and targeting), membrane structural components, cell division, and proteasome processes. The transcriptomes of control wild type and 5 suppressor strains overexpressing ARL1, BCK2, ERG24, MSG5, or RBA50, were analyzed in the presence and absence of COS. Some of the up-regulated transcripts in the suppressor overexpressing strains exposed to COS included genes involved in transcription, cell cycle, stress response and the Ras signal transduction pathway. Down-regulated transcripts included those encoding protein folding components and respiratory chain proteins. The COS-induced transcriptional response is distinct from previously described environmental stress responses (i.e. thermal, salt, osmotic and oxidative stress) and pre-treatment with these well characterized environmental stressors provided little or any resistance to COS. Conclusions: Overexpression of the ARL1 gene, a member of the Ras superfamily that regulates membrane trafficking, provides protection against COS-induced cell membrane permeability and damage. We found that the ARL1 COS-resistant over-expression strain was as sensitive to Amphotericin B, Fluconazole and Terbinafine as the wild type cells and that when COS and Fluconazole are used in combination they act in a synergistic fashion. The gene targets of COS identified in this study indicate that COS’s mechanism of action is different from other commonly studied fungicides that target membranes, suggesting that COS may be an effective fungicide for drug-resistant fungal pathogens.

Búsqueda colaborativa para el apoyo a la recomendación de Objetos de Aprendizaje

Este trabajo propone un marco para la búsqueda, selección, valoración y recomendación tanto individual como en grupo de objetos de aprendizaje implementado dentro del sistema de recomendación hibrido DELPHOS. Para facilitar la búsqueda colaborativa se utilizan varias aproximaciones de creación de grupos. También se van a facilitar varias funciones colaborativas como la calificación, el etiquetado y la posibilidad de comentar los objetos. Finalmente se proporcionan varias actividades sociales para poder añadir o recomendar objetos a un grupo, visualizar y calificar objetos añadidos por otros usuarios del grupo, y comunicarse mediante chat o correo electrónico con otros miembros del mismo para llegar a tomar decisiones sobre los objetos más adecuados para los intereses del grupo.

La investigación en ciencias de la salud en Ecuador. Un análisis en el contexto latinoamericano

Antecedentes/Objetivos: La investigación es una necesidad común, sin embargo, las características y el contexto de los distintos países hace que la producción de la misma difiera considerablemente. El presente estudio bibliométrico tiene como objetivo describir la investigación en ciencias de la salud en Ecuador en el contexto Latinoamericano, durante el período 1996-2012. Métodos: Para el análisis se hizo uso de indicadores existentes en las bases de datos Scimago y Scopus. Se seleccionó estratégicamente a 3 países para ser comparados con la producción científica en ciencias de la salud ecuatoriana, tomando en cuenta a Brasil, México y Bolivia. Se analizaron las categorías: “Medicina”, “Enfermería”, “Nutrición y Dietética”, “Salud Pública” y “Epidemiología”, que tienen relación con ciencias de la salud y se encuentran contempladas dentro del “Plan Nacional del Buen Vivir” de Ecuador. Se analizó el número total de publicaciones en este período de tiempo, el ranking por país según número de publicaciones, el índice-H, las instituciones de mayor producción científica, los máximos productores y la colaboración internacional en publicaciones científicas. Se utilizaron las herramientas de ranking por país y comparar de Scimago y para la identificación tanto de “instituciones de excelencia” “ como de “grandes productores” se utilizó la herramienta ranking de Scopus. Resultados: Se encontró que en todas las categorías Brasil ocupa el puesto 1 y tiene el índice-H más alto, seguido por México en ranking e índice-H, Ecuador está por debajo de estos dos países pero supera a Bolivia. En cuanto a los grupos de excelencia en investigación, se encontró que dentro de los 10 primeros, solo 5 son universidades y el 60% pertenecen al sector privado, la institución que más publicaciones científicas tiene es la Universidad Central del Ecuador y el máximo productor en el Ecuador es Del Brutto, O.H. En lo referente a la colaboración científica internacional en ciencias de la salud, Ecuador recibe entre 57,8 y 100%. Conclusiones: De lo analizado se puede decir que la contribución de la investigación en ciencias de la salud en Ecuador en el contexto Latinoamericano es baja, con un despunte a partir del año 2003, que supera en incremento porcentual a México y Bolivia, este despunte podría deberse en parte a que en el Ecuador, en el año 2002 se establece la Política y la Ley del Sistema Nacional de Salud, que da inicio en octubre del mismo año al Foro Nacional de Investigación en Salud y para marzo del 2004, se instala la Comisión de Ciencia y Tecnología del Consejo Nacional de Salud), sin embargo son necesarios más esfuerzos del Gobierno ecuatoriano para desarrollar una política de I+D efectiva.

Analysis of the Connecting Zone between Consecutive Sections in Distillation Columns Covering Multiple Feeds, Products and Heat Transfer Stages

In the present work, we provide a systematic analysis about all tine streams involved in the zone connecting two consecutive sections for the design of distillation columns with different thermal feed conditions, product extractions and heat additions or withdrawals. This analysis allows a better understanding of what happens on a feed or side draw (of mass or energy) stage, what compositions are or are not in equilibrium, and the impact on internal liquid and vapor flows.

Intramolecular surfaces for vicinal proton–proton coupling constants 3JHH

Equations for the intramolecular surfaces of the 3JHH coupling constants in ethane, ethylene, and acetylene are formulated, and the corresponding coefficients are estimated from calculations at the DFT/B3LYP level. The chosen variables are changes in bond lengths, in the torsion angle φ between the coupled protons Ha and Hb, in bond angles, and in dihedral angles. The 3JHH surface of ethane is formulated as an extended Karplus equation with the coefficients of a truncated Fourier series on the torsion angle φ expanded as second-order Taylor series in the chosen variables taking into account the invariance of 3JHH under reflections and rotations of nuclear coordinates. Partial vibrational contributions from linear and square terms corresponding to changes in the geometry of the Ha − Ca − Cb − Hb fragment are important while those from cross terms are small with a few exceptions. The 3JHH surface of ethane is useful to predict contributions to 3JHH from changes in local geometry of derivatives but vibrational contributions are predicted less satisfactorily. The predicted values at the B3LYP/BS2 level of the 3JHH couplings (vibrational contributions at 300 K) from equilibrium geometries are 9.79 (−0.17) for acetylene, and 17.08 (1.93) and 10.73(0.93) for the trans and cis couplings of ethylene.

Enzyme mediated synthesis of polypyrrole in the presence of chondroitin sulfate and redox mediators of natural origin

Polypyrrole (PPy) was synthesized by enzyme mediated oxidation of pyrrole using naturally occurring compounds as redox mediators. The catalytic mechanism is an enzymatic cascade reaction in which hydrogen peroxide is the oxidizer and soybean peroxidase, in the presence of acetosyringone, syringaldehyde or vanillin, acts as a natural catalysts. The effect of the initial reaction composition on the polymerization yield and electrical conductivity of PPy was analyzed. Morphology of the PPy particles was studied by scanning electron microscopy and transmission electron microscopy whereas the chemical structure was studied by X-ray photoelectron and Fourier transformed infrared spectroscopic techniques. The redox mediators increased the polymerization yield without a significant modification of the electronic structure of PPy. The highest conductivity of PPy was reached when chondroitin sulfate was used simultaneously as dopant and template during pyrrole polymerization. Electroactive properties of PPy obtained from natural precursors were successfully used in the amperometric quantification of uric acid concentrations. PPy increases the amperometric sensitivity of carbon nanotube screen-printed electrodes toward uric acid detection.

Bimetallic PtSn/C catalysts obtained via SOMC/M for glycerol steam reforming

A detailed study on the preparation of bimetallic PtSn/C catalysts using surface-controlled synthesis methods, and on their catalytic performance in the glycerol steam reforming reaction has been carried out. In order to obtain these well-defined bimetallic phases, techniques derived from Surface Organometallic Chemistry on Metals (SOMC/M) were used. The preparation process involved the reaction between an organometallic compound ((C4H9)4Sn) and a supported transition metal (Pt) in a H2 atmosphere. Catalysts with Sn/Pt atomic ratios of 0.2, 0.3, 0.5, and 0.7 were obtained, and characterized using several techniques: ICP, H2 chemisorption, TEM and XPS. These systems were tested in the glycerol steam reforming varying the reaction conditions (glycerol concentration and reaction temperature). The best performance was observed for the catalysts with the lowest tin contents (PtSn0.2/C and PtSn0.3/C). It was observed that the presence of tin increased the catalysts’ stability when working under more severe reaction conditions.

Direct synthesis of β-ketophosphonates and vinyl phosphonates from alkenes or alkynes catalyzed by CuNPs/ZnO

Copper nanoparticles (CuNPs) supported on ZnO have been shown to effectively catalyze the direct synthesis of β-ketophosphonates from alkenes or alkynes, and that of vinyl phosphonates from alkynes and diethylphosphite, under air and in the absence of any additive or ligand. When using alkynes as starting materials, the selectivity proved to be dependent on the nature of the alkyne. Thus, alkynes conjugated with an aromatic ring or a carbon–carbon double bond gave β-ketophosphonates as the main reaction products, whereas aliphatic alkynes or alkynes conjugated with a carbonyl group led to the formation of the corresponding vinyl phosphonates.

Copper Nanoparticles in Click Chemistry

Conspectus: The challenges of the 21st century demand scientific and technological achievements that must be developed under sustainable and environmentally benign practices. In this vein, click chemistry and green chemistry walk hand in hand on a pathway of rigorous principles that help to safeguard the health of our planet against negligent and uncontrolled production. Copper-catalyzed azide–alkyne cycloaddition (CuAAC), the paradigm of a click reaction, is one of the most reliable and widespread synthetic transformations in organic chemistry, with multidisciplinary applications. Nanocatalysis is a green chemistry tool that can increase the inherent effectiveness of CuAAC because of the enhanced catalytic activity of nanostructured metals and their plausible reutilization capability as heterogeneous catalysts. This Account describes our contribution to click chemistry using unsupported and supported copper nanoparticles (CuNPs) as catalysts prepared by chemical reduction. Cu(0)NPs (3.0 ± 1.5 nm) in tetrahydrofuran were found to catalyze the reaction of terminal alkynes and organic azides in the presence of triethylamine at rates comparable to those achieved under microwave heating (10–30 min in most cases). Unfortunately, the CuNPs underwent dissolution under the reaction conditions and consequently could not be recovered. Compelling experimental evidence on the in situ generation of highly reactive copper(I) chloride and the participation of copper(I) acetylides was provided. The supported CuNPs were found to be more robust and efficient catalyst than the unsupported counterpart in the following terms: (a) the multicomponent variant of CuAAC could be applied; (b) the metal loading could be substantially decreased; (c) reactions could be conducted in neat water; and (d) the catalyst could be recovered easily and reutilized. In particular, the catalyst composed of oxidized CuNPs (Cu2O/CuO, 6.0 ± 2.0 nm) supported on carbon (CuNPs/C) was shown to be highly versatile and very effective in the multicomponent and regioselective synthesis of 1,4-disubstituted 1,2,3-triazoles in water from organic halides as azido precursors; magnetically recoverable CuNPs (3.0 ± 0.8 nm) supported on MagSilica could be alternatively used for the same purpose under similar conditions. Incorporation of an aromatic substituent at the 1-position of the triazole could be accomplished using the same CuNPs/C catalytic system starting from aryldiazonium salts or anilines as azido precursors. CuNPs/C in water also catalyzed the regioselective double-click synthesis of β-hydroxy-1,2,3-triazoles from epoxides. Furthermore, alkenes could be also used as azido precursors through a one-pot CuNPs/C-catalyzed azidosulfenylation–CuAAC sequential protocol, providing β-methylsulfanyl-1,2,3-triazoles in a stereo- and regioselective manner. In all types of reaction studied, CuNPs/C exhibited better behavior than some commercial copper catalysts with regard to the metal loading, reaction time, yield, and recyclability. Therefore, the results of this study also highlight the utility of nanosized copper in click chemistry compared with bulk copper sources.