4 resultados para 3-18

em Universidad de Alicante


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Resumen de Tesis Doctoral, Departamento de Ciencias de la Vida, Universidad de Alcalá. 16 Mayo 2013, Directores: Miguel A. Zavala, Lorena Gómez-Aparicio.

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During the 1860's and 1870's, Spain and Italy experienced a convergence of debates on the significance of political representation in the framework of Liberal State. Spain suffered a political and social crisis, ending with the Revolution of 1868 and the adoption of male universal suffrage in 1878. Its coeval Italy began to build its new Kingdom, anxious about state building, as well as the relevance of electoral processes in the Constitutional scheme. Although members of parliament and essayists of both countries well knew their neighbour's political reality, a dialogue on representation didn't occur. Nonetheless, we believe it is useful to analyse the survey drawn by the Italian publicist in the light of current knowledge of the opinions that prevailed in Spain. What sense did they give to the general election? How did they understand the value of the vote? Who were considered eligible voters? These questions comprise the main subjects of the essay.

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Background: Celiac disease (CD) has a negative impact on the health-related quality of life (HRQL) of affected patients. Although HRQL and its determinants have been examined in Spanish CD patients specifically recruited in hospital settings, these aspects of CD have not been assessed among the general Spanish population. Methods: An observational, transversal study of a non-randomized, representative sample of adult celiac patients throughout all of Spain's Autonomous Regions. Subjects were recruited through celiac patient associations. A Spanish version of the self-administered Celiac Disease-Quality of Life (CD-QOL) questionnaire was used. Determinant factors of HRQL were assessed with the aid of multivariate analysis to control for confounding factors. Results: We analyzed the responses provided by 1,230 patients, 1,092 (89.2%) of whom were women. The overall mean value for the CD-QOL index was 56.3 ± 18.27 points. The dimension that obtained the most points was dysphoria, with 81.3 ± 19.56 points, followed by limitations with 52.3 ± 23.43 points; health problems, with 51.6 ± 26.08 points, and inadequate treatment, with 36.1 ± 21.18 points. Patient age and sex, along with time to diagnosis, and length of time on a gluten-free diet were all independent determinant factors of certain dimensions of HRQL: women aged 31 to 40 expressed poorer HRQL while time to diagnosis and length of time on a gluten-free diet were determinant factors for better HRQL scores. Conclusions: The HRQL of adult Spanish celiac subjects is moderate, improving with the length of time patients remain on a gluten-free diet.