Value Assessment of Orphan Drugs and Treatments for Rare Diseases

Thesis (Master's)--University of Washington, 2016-06

A Kaleidoscope Perspective: Change in the Semantics and Structure of Facets and Isolates in Analytico-Synthetic Classification

Examines the limitations of the dynamic theory of classification in accommodating the changes and rapid growth of new topics in the universe of knowledge. Change in an analytico-synthetic scheme for classification is much more a web of connections and mapping these changes is a complex process. Suggests that there is need for exploration of this complexity for both improving systems, and revisiting our theory.