3 resultados para microstructured fabrication

em University of Queensland eSpace - Australia


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We comment on the recent Letter by Argyros et al. [Opt. Lett. 29, 1882 (2004)] in which a microstructured polymer fiber doped with the dye Rhodamine 6G was discussed as a possible fiber laser source. We suggest that the lasing action at 632 nm was due to stimulated Raman scattering in the poly(methyl methacrylate) host material. (c) 2005 Optical Society of America.

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In this study, we investigate the fabrication of 3D porous poly(lactic-co-glycolic acid) (PLGA) scaffolds using the thermally-induced phase separation technique. The current study focuses on the selection of alternative solvents for this process using a number of criteria, including predicted solubility. toxicity, removability and processability. Solvents were removed via either vacuum freeze-drying or leaching, depending on their physical properties. The residual solvent was tested using gas chromatography-mass spectrometry. A large range of porous, highly interconnected scaffold architectures with tunable pore size and alignment was obtained, including combined macro- and microporous structures and an entirely novel 'porous-fibre' structure. The morphological features of the most promising poly(lactic-co-glycolic acid) scaffolds were analysed via scanning electron microscopy and X-ray micro-computed tomography in both two and three dimensions. The Young's moduli of the scaffolds under conditions of temperature, pH and ionic strength similar to those found in the body were tested and were found to be highly dependent on the architectures.