Insulin sensitivity measures in cats exhibit high inter-day variability

In cats with underlying low insulin sensitivity, obesity is a major risk factor for type 2 diabetes. Strategies to prevent the onset of type 2 diabetes could be implemented if these cats could be identified. Currently, two labour-intensive and complex methods have been used to measure insulin sensitivity in research studies: the hyperinsulinemic euglycemic clamp (Clamp) and the minimal model analysis (MINMOD) of a frequentlysampled intravenous glucose tolerance test. However, simpler measures are required in practice. Validation of simple measures requires a wellestablished method with minimal inter-day variability. The aims of this study were to determine the inter-day variability of the current methods of measuring insulin sensitivity in cats, and to assess the relationship between these tests and simpler measures of insulin sensitivity.

Folk singers during Labour Day march Brisbane 1965

Folk singers during the Labor Day procession, in Brisbane, Australia, May 1965. One person holds a banner relating to the S.S. Binburra

Trucks with banners in Brisbane 1965 during Labor Day procession.

Trucks with banners in Brisbane, Australia, during the Labor Day procession, May 1965.

Queensland Trades and Labor Council float with banner during Labour Day march Brisbane 1965

Queensland Trades and Labor Council float with banner during the Labor Day procession, May 1965, Brisbane Australia.

Participants with Equal pay placard during Labour Day march Brisbane 1965

Participants with Equal pay placard in Brisbane, Australia, during the Labor Day procession, May 1965.

Marchers with banners during Labour Day march Brisbane 1965

Marchers with banners in Brisbane, Australia, during the Labor Day procession, May 1965.