Internal hallway, Powell House, Noosa River, Sunshine Coast

View down hall to living room.

Dining and living room areas, Powell House, Noosa River, Sunshine Coast

View through dining and living room areas to external deck.

Dining and kitchen areas, Powell House, Noosa River, Sunshine Coast

View from living room to kitchen.

Powell House, Noosa River, Sunshine Coast

Timber deck with sliding timber shutters off the master bedroom

Timber-framed windows, Powell House, Noosa River, Sunshine Coast

Folding timber windows and roof over.

Powell House, Noosa River, Sunshine Coast

As seen from neighbouring property.

The origin of a Robertsonian chromosomal translocation in house mice inferred from linked microsatellite markers

The Western European house mouse, Mus domesticus, includes many distinct Robertsonian (Rb) chromosomal races. Two competing hypotheses may explain the distribution of Rb translocations found in different populations: they may have arisen independently multiple times or they may have arisen once and been spread through long distance dispersal. We investigated the origin of the Rb 5.15 translocation using 6 microsatellite loci linked to the centromeres of chromosomes 5 and 15 in 84 individuals from 3 Rb populations and 4 neighboring standard-karyotype populations. Microsatellite variation on the 5.15 metacentric chromosomes was significantly reduced relative to the amount of variation found on acrocentric chromosomes 5 and 15, suggesting that linked microsatellite loci can track specific mutational events. Phylogenetic analyses resulted in trees which are consistent with multiple origins of the 5.15 metacentric found in the three Rb populations. These results suggest that cytologically indistinguishable mutations have arisen independently in natural populations of house mice.

Slotted timber skin, Sunshine Beach House, Sunshine Coast

As seen from exterior.

Parliament House Competition Model, Canberra

View of model for competition entry.