1 resultado para 390200 Professional Development of Law Practitioners
em SAPIENTIA - Universidade do Algarve - Portugal
Resumo:
In order to produce packaging films with a broad spectrum of action on microorganisms, the
effect of two antimicrobial (AM) to be included in the films, carvacrol and GSE were studied
separately on different microorganisms. Carvacrol was more effective against the grampositive
bacteria than against the gram-negative bacterium. GSE was not effective against
yeast. Subsequently, a search for optimal combinations of carvacrol, GSE and the addition of
chitosan (as a third component with film forming properties) was carried out. Response
surface analysis showed several synergetic effects and three optimal AM combinations
(OAMC) were obtained for each microorganism. The experimental validation confirmed that
the optimal solutions found can successfully predict the response for each microorganism.
The optimization of mixtures of the three components, but this time, using the same
concentration for all microorganisms, was also studied to obtain an OAMC with wide spectrum
of activity. The results of the response surface analysis showed several synergistic effects for
all microorganisms. Three OAMC, OAMC-1, OAMC-2, OAMC-3, were found to be the optimal
mixtures for all microorganisms. The radical scavenging activity (RSA) of the different agents
was then compared with a standard antioxidant (AOX) BHT, at different concentrations; as also
at the OAMC. The RSA increased in the following order: chitosan