IDEAhaus: A Comfortable Home for the UK’s Future Climate

IDEAhaus:
A Comfortable Home for the UK’s Future Climate

This paper describes the result of a project to develop climate adaptation design strategies funded by the UK’s Technology Strategy Board. The aim of the project was to look at the threats and opportunities presented by industrialised and lightweight housebuilding techniques in the light of predicted increases in flooding and overheating. This case study presents detailed concept designs for a future systemised housing product which can be Industrialised, Delightful, Efficient and Adaptable; an IDEAhaus.
Keywords: climate change adaptation, thermal comfort, passive cooling, flood residence, industrialised housing, mass customisation

Identification of an unknown b-agonist in feed by liquid chromatography/bioassay/quadrupole time-of-flight tandem mass spectrometry with accurate mass measurement.

A new approach to the search for residues of unknown growth promoting agents such as anabolic steroids and -agonists in feed is presented. Following primary extraction and clean-up, samples are separated using gradient liquid chromatography (LC). The effluent is split towards two identical 96-well fraction collectors and an optional electrospray quadrupole time-of-flight mass spectrometry (QTOFMS) system for accurate mass measurement. One 96-well plate is used for a bioassay (enzyme-immuno assay, receptor assay) and will detect the bioactivity and position of the relevant peak in the chromatogram. The positive well in the second 96-well plate is used for identification by LC/QTOFMS/MS. The value of this LC/bioassay/QTOFMS/MS methodology is highlighted by the finding and structure elucidation of a new -agonist in a feed extract.