29 resultados para André
em QUB Research Portal - Research Directory and Institutional Repository for Queen's University Belfast
Resumo:
A partir du portrait de Charles de Gaulle brossé par André Malraux dans Les Chênes qu’on abat (1971), l’article cherche à analyser et à évaluer le statut de ce héros national français afin de déterminer dans quelle mesure le général peut être considéré comme un grand homme de l’Europe. Le statut et le destin du général étant étroitement liés à ceux de la France, l’article tente de caractériser la place de ce grand homme ainsi que celle de la France dans l’Europe d’après la Deuxième Guerre mondiale. Les deux perspectives temporelles de la durée, d’une part, et des événements, de l’autre, contribuent ici à nuancer le portrait de ce grand homme à la fois profondément engagé dans l’histoire de son temps et pourtant représentant d’une continuité historique. Mots-clé: de Gaulle, Malraux, France, Europe, héros, nation
Resumo:
The article presented to Malraux specialists the conclusions and findings of the international conference on André Malraux held at Queen's University Belfast in 2007.
Resumo:
Les vies et les carrières d’André Chamson et d’André Malraux se ressemblent par de multiples aspects. Contemporains, ils se connaissaient bien, menaient souvent les mêmes combats, souffraient des mêmes préoccupations, Mais c’est surtout par rapport à l’esprit qui les animait, en tant que grandes personnalités marquantes du XXe siècle, que d’intéressants parallèles peuvent être établis entre eux, que nous pouvons avec profit examiner les valeurs universelles et spirituelles qu’ils promouvaient, valeurs emblématiques pour tant de penseurs, d’acteurs, et d’écrivains de ce siècle. Ainsi pourrions-nous par ailleurs interroger et même évaluer la solidité, la résistance et le potentiel de telles valeurs pour le siècle à venir.
Resumo:
This article contextualises Malraux' s last novel, written during WWII, within French Literary and politico philosophical traditions (Fustel de Coulanges, Renan, Peguy, Barres, Claudel) in order to explain the author's often misrepresented conversion from Internationalism to Gaullism. Literary motives in the novel are discussed in the light of a continued debate with German thinkers (Treitschke, Strauss, Nietzsche) throughout Malraux's oeuvre. It is shown that Malraux, while literarily at his most barresian, subverts Barres's Nationalism to embrace Nietzsche's ideas, while in turn, he finds in German philosophy a reason to fight, both in the novel and through his military "engagement", against Germany.
Resumo:
Aims/hypothesis: The impact of AGEs and advanced lipoxidation end-products (ALEs) on neuronal and Müller glial dysfunction in the diabetic retina is not well understood. We therefore sought to identify dysfunction of the retinal Müller glia during diabetes and to determine whether inhibition of AGEs/ALEs can prevent it.
Methods: Sprague-Dawley rats were divided into three groups: (1) non-diabetic; (2) untreated streptozotocin-induced diabetic; and (3) diabetic treated with the AGE/ALE inhibitor pyridoxamine for the duration of diabetes. Rats were killed and their retinas were evaluated for neuroglial pathology. Results: AGEs and ALEs accumulated at higher levels in diabetic retinas than in controls (p<0.001). AGE/ALE immunoreactivity was significantly diminished by pyridoxamine treatment of diabetic rats. Diabetes was also associated with the up-regulation of the oxidative stress marker haemoxygenase-1 and the induction of glial fibrillary acidic protein production in Müller glia (p<0.001). Pyridoxamine treatment of diabetic rats had a significant beneficial effect on both variables (p<0.001). Diabetes also significantly altered the normal localisation of the potassium inwardly rectifying channel Kir4.1 and the water channel aquaporin 4 to the Müller glia end-feet interacting with retinal capillaries. These abnormalities were prevented by pyridoxamine treatment.
Conclusions/interpretation: While it is established that AGE/ALE formation in the retina during diabetes is linked to microvascular dysfunction, this study suggests that these pathogenic adducts also play a role in Müller glial dysfunction.