'Small places like St Helena have big questions to ask': the inaugural lecture of a Professor of Island Geography

This publication takes the form of a written version of my inaugural lecture, which was presented at Queen’s University Belfast on 10 March 2010. It is more personal and considerably more self-indulgent than would normally be acceptable in an article, with more of my own experiences and also my own references than would usually be considered proper. However, the bestowal of such a title as Professor of Island Geography is something of a marker of the maturity not just of myself but maybe also for island studies. After a section describing my path into island geography, the lecture deals with the negativities of islands and the seeming futility of studying them only then to identify a new or at least enhanced regard for islands as places with which to interact and to examine. Reference is made to islands throughout the world, but with some focus on the small islands off Ireland. The development of island studies as a discipline is then briefly described before the lecture concludes with reference to its title quotation on St Helena by considering that place’s islandness and how this affected/affects it in both the 17th and 21st centuries.

A long-term study (1949-2005) of experimental introductions to an island; freshwater amphipods (Crustacea) in the Isle of Man (British Isles)

Using data from field introduction experiments with Gammarus spp. conducted in the rivers of a small island, commencing in 1949, with resampling in the 60s, 70s, 80s, 90s and finally in 2005, we aimed to examine the long-term interaction of the native freshwater amphipod Gammarus duebeni celticus with the introduced G. pulex. Using physico-chemical data from a 2005 island-wide survey, we also aimed to find what environmental factors could influence the distribution of the two species.

Sea turtle diving and foraging behaviour around the Greek Island of Kefalonia

The discovery of a shallow water (

Temporal characterization and in vitro comparison of cell survival following the delivery of 3D-conformal, intensity-modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT)

A phantom was designed and implemented for the delivery of treatment plans to cells in vitro. Single beam, 3D-conformal radiotherapy (3D-CRT) plans, inverse planned five-field intensity-modulated radiation therapy (IMRT), nine-field IMRT, single-arc volumetric modulated arc therapy (VMAT) and dual-arc VMAT plans were created on a CT scan of the phantom to deliver 3 Gy to the cell layer and verified using a Farmer chamber, 2D ionization chamber array and gafchromic film. Each plan was delivered to a 2D ionization chamber array to assess the temporal characteristics of the plan including delivery time and 'cell's eye view' for the central ionization chamber. The effective fraction time, defined as the percentage of the fraction time where any dose is delivered to each point examined, was also assessed across 120 ionization chambers. Each plan was delivered to human prostate cancer DU-145 cells and normal primary AGO-1522b fibroblast cells. Uniform beams were delivered to each cell line with the delivery time varying from 0.5 to 20.54 min. Effective fraction time was found to increase with a decreasing number of beams or arcs. For a uniform beam delivery, AGO-1552b cells exhibited a statistically significant trend towards increased survival with increased delivery time. This trend was not repeated when the different modulated clinical delivery methods were used. Less sensitive DU-145 cells did not exhibit a significant trend towards increased survival with increased delivery time for either the uniform or clinical deliveries. These results confirm that dose rate effects are most prevalent in more radiosensitive cells. Cell survival data generated from uniform beam deliveries over a range of dose rates and delivery times may not always be accurate in predicting response to more complex delivery techniques, such as IMRT and VMAT.