233 resultados para AFRICAN LITERATURE
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We describe the isolation and structural characterization of a family of antimicrobial peptides related to kassinatuerin-2, from the skin secretion of the African hyperoliid frog, Kassina maculata. All four peptides, designated kassinatuerin-2Ma through Md, are C-terminally-amidated 20-mers with the consensus sequence – FX1GAIAAALPHVIX2AIKNAL – where X1 = L/F/V/I and X2 = S/N. All four peptides are encoded by precursors of 69 amino acids. Synthetic replicates of all kassinatuerin-2 related peptides displayed a potent inhibitory activity against Staphylococcus aureus with a minimal inhibitory concentration of 16 µM, at which concentration, however, they effected 18% haemolysis of horse erythrocytes after 2 h. Despite obvious membranolytic properties, all peptides were ineffective at inhibiting the growth of Escherichia coli at concentrations up to 200 µM and were relatively ineffective against Candida albicans (MIC 120 µM). The kassinatuerin-2 related peptides of K. maculata skin secretion thus possess a discrete antimicrobial and weak haemolytic activity in contrast to the prototype kassinatuerin-2 from the skin secretion of Kassina senegalensis.
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Beginning with a panoramic analysis of the role played by East Timorese poets in the struggle for liberation from Portuguese and Indonesian colonial rule, this article examines the extent to which an East Timorese national identity and unity repeatedly featured in the poetry of the 1970s and 80s are represented in contemporary Timorese literary production. By reading the work of the novelist Luís Cardoso, and the poets Abé Barreto and Celso Oliveira, the article also assesses whether the independent nation envisioned earlier by those such as Borja da Costa, Fernando Sylvan and Xanana Gusmão, has been realised. In doing so, critical attention is brought to bear on the intimate relationship between the specific material and political circumstances of East Timor and the literature produced in colonial and postcolonial moments in the nation’s history.
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This paper investigates if benchmark African equity indices exhibit the stylized facts reported for financial time-series returns. The returns distributions of the Africa All-Share, Large, Medium and Small Company Indices were found to be leptokurtotic, had fat-tails, over time experienced volatility clustering and exhibited long memory in volatility. Both the All-Share and Large Company Indices were found to exhibit leverage effects. In contrast, positive shocks had a greater impact on future volatility for the Small Company Index which implies a reverse leverage effect. This finding could reflect a bull/bubble market for small capitalisation stocks in Africa.